Fluorine-free preparation of titanium carbide MXene quantum dots with high near-infrared photothermal performances for cancer therapy

Nanoscale ◽  
2017 ◽  
Vol 9 (45) ◽  
pp. 17859-17864 ◽  
Author(s):  
Xinghua Yu ◽  
Xingke Cai ◽  
Haodong Cui ◽  
Seung-Wuk Lee ◽  
Xue-Feng Yu ◽  
...  

Titanium carbide MXene QDs were synthesized using a newly-developed fluorine-free method. Significantly, they exhibit very high extinction coefficient and photothermal conversion efficiency, and great biocompatibility, showing high potential for PTT applications.

Nanoscale ◽  
2019 ◽  
Vol 11 (19) ◽  
pp. 9760-9768 ◽  
Author(s):  
He Hu ◽  
Qi Yang ◽  
Simona Baroni ◽  
Hong Yang ◽  
Silvio Aime ◽  
...  

The Gd-TMV–PDA nanotheranostic reagents demonstrated highly r1-relaxivity of ∼80 mM−1 s−1 at 60 MHz, strong near-infrared absorption with high photothermal conversion efficiency (28.9%), excellent photoacoustic contrast and good biocompatibility.


2019 ◽  
Vol 7 (14) ◽  
pp. 2247-2251 ◽  
Author(s):  
Lu Li ◽  
Qingzhu Yang ◽  
Lei Shi ◽  
Nannan Zheng ◽  
Zeyu Li ◽  
...  

Novel phthalocyanine molecule 4OCSPC with deep NIR absorbance showed excellent photothermal therapy property for cancer cells.


Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1776 ◽  
Author(s):  
Wenhao Dai ◽  
Haifeng Dong ◽  
Xueji Zhang

Theranostic platforms integrating imaging diagnostic and therapeutic interventions into a single nanoplatform have attracted considerable attention for cancer-individualized therapies. However, their uncertain stability, complex pharmacokinetics, and intrinsic toxicology of multiple components hinder their practical application in clinical research. In this paper, stable and high-concentration molybdenum carbide quantum dots (Mo2C QDs) with a diameter of approximately 6 nm and a topographic height of about 1.5 nm were synthesized using a facile sonication-assisted liquid-phase exfoliation approach. The prepared Mo2C QDs exhibited a strong near-infrared (NIR) absorbance with a high molar extinction coefficient of 4.424 Lg−1cm−1 at 808 nm, a high photothermal conversion efficiency of 42.9%, and showed excellent performance on photoacoustic imaging. The Mo2C QDs had high stability and highly biocompatibility, with low cytotoxicity. Under NIR irradiation, a remarkable in vitro and in vivo therapeutic effect was obtained. Such a stable and biocompatible all-in-one theranostic nanoagent generated by facile synthesis that combines promising imaging guidance and effective tumor ablation properties may hold great potential for theranostic nanomedicine.


Nanoscale ◽  
2021 ◽  
Author(s):  
Qing Xu ◽  
Danyang Li ◽  
Haijun Zhou ◽  
Biaoqi Chen ◽  
Junlei Wang ◽  
...  

We describe the synthesis of MnO2-coated porous Pt@CeO2 core–shell nanostructures (Pt@CeO2@MnO2) as a new theranostic nano-platform. The porous Pt cores endow the core–shell nanostructures with high photothermal conversion efficiency (80%)...


2014 ◽  
Vol 43 (30) ◽  
pp. 11709 ◽  
Author(s):  
Xijian Liu ◽  
Bo Li ◽  
Fanfan Fu ◽  
Kaibing Xu ◽  
Rujia Zou ◽  
...  

2015 ◽  
Vol 51 (20) ◽  
pp. 4223-4226 ◽  
Author(s):  
Shuo Huang ◽  
Ravi Kumar Kannadorai ◽  
Yuan Chen ◽  
Quan Liu ◽  
Mingfeng Wang

A novel photothermal therapeutic agent based on a narrow-bandgap benzobisthiadiazole derivative shows strong absorption in the near-infrared region, high photothermal efficiency and robust photostability for treatment of cancer cells.


Nanoscale ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 2655-2667 ◽  
Author(s):  
Xuyang Sun ◽  
Mengmeng Sun ◽  
Miaomiao Liu ◽  
Bo Yuan ◽  
Weiping Gao ◽  
...  

Shape tunable liquid metal nanoparticles were fabricated with characterization of biocompatibility, favorable photothermal conversion efficiency and tumor targeting capability for photothermal therapy.


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