scholarly journals Simplified identification of disulfide, trisulfide, and thioether pairs with 213 nm UVPD

The Analyst ◽  
2018 ◽  
Vol 143 (21) ◽  
pp. 5176-5184 ◽  
Author(s):  
James Bonner ◽  
Lance E. Talbert ◽  
Nicholas Akkawi ◽  
Ryan R. Julian

Disulfide heterogeneity and other non-native crosslinks introduced during therapeutic antibody production and storage could have considerable negative effects on clinical efficacy, but tracking these modifications remains challenging.


2006 ◽  
Vol 5 (4) ◽  
pp. 16-25 ◽  
Author(s):  
Feng Li ◽  
Brian Lee ◽  
Joe Zhou ◽  
Tim Tressel ◽  
Xiaoming Yang




2021 ◽  
Author(s):  
Nadja Raab ◽  
Nikolas Zeh ◽  
Patrick Schlossbauer ◽  
Sven Mathias ◽  
Benjamin Lindner ◽  
...  


2018 ◽  
Vol 102 (14) ◽  
pp. 6081-6093 ◽  
Author(s):  
Yafang Lu ◽  
Qin Zhou ◽  
Qianqian Han ◽  
Pengfei Wu ◽  
Lanlan Zhang ◽  
...  


2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Jeffrey D. Goby ◽  
Kenji Furuya ◽  
Eike Zimmermann ◽  
Justin A. Beller ◽  
John M. Schmitt ◽  
...  




Author(s):  
Huynh Nguyen Duy Bao ◽  
Sigurjón Arason ◽  
Kristín Anna Þórarinsdóttir

The influence of different cooling techniques (dry ice/ice packs) and storage temperature (-2°C/3°C) to prolong the shelf life of Arctic charr (Salvelinus alpinus) fillets were evaluated by sensory analysis, physical methods, chemical and microbial analysis. The effects of storage temperature were stronger than of different cooling agents. Superchilling (-2°C) of fillets packed with dry ice resulted in 6 days extension of shelf life compared to chilling (3°C). The use of dry ice parallel to superchilling prolonged shelf life for 1 day compared to fillets stored with ice packs. No negative effects on quality of the fillets where detected that could be linked to cell destruction caused by partial freezing or to sour taste, caused by absorption of CO2 gas in fish flesh.



2021 ◽  
Vol 891 (1) ◽  
pp. 012018
Author(s):  
R Maharani ◽  
A Fernandes

Abstract The COVID-19 pandemic that occurred in most areas of the world caused many negative effects, including health, social and economic declined. One alternative to prevented it is to make immunostimulant supplements from natural resources that are available in surrounding environment along with encouraging development of home industries to produce them. In Kalimantan, Indonesia, one of the natural sources that have been utilized and proven locally as a medicinal plant is Bawang Dayak (Eleutherine bulbosa). One of its functions is as an immunostimulant supplement, but until now there has not been much research on the manufacture of E. bulbosa as a home industry product that functions as an immunostimulant supplement. E.bulbosa was demonstrated high antioxidant activity 1.48 μg/ml IC50 value and significantly increased immunity. The E.bulbosa was also contained iso-eleutherine and iso-eleutherol which have the potential as an anti-virus. In this study, several E. bulbosa derivated products, namely teabags and infusions, were introduced and compared starting from technical process, economic analysis, and storage period. Recent study showed that 1 kg of E. bulbosa can produce about 20 boxes of teabags (10 tea bags/box) that can be stored for 6-12 months, with a total profit reached 2-3 times of total production cost. While, 1 kg E. bulbosa was produced 16 bottles containing 330ml infusion drink which can be stored for 3-5 days in refrigerator, and it was provided 2 times profit of total production cost. However, these two products can be used as an alternative to stay healthy along with increase in added value and income for communities.



2020 ◽  
Vol 1 (1) ◽  
pp. 42-53
Author(s):  
Janinah Baclaocos ◽  
John James Mackrill

Background: In animals, the 21st amino acid selenocysteine is incorporated into a restricted subset of proteins by recoding of a UGA stop codon. This recoding requires a distinctive selenocysteine insertion sequence in selenoprotein encoding mRNAs, trans-acting factors and in most cases, adequate dietary intake of selenium. With one exception, selenoproteins contain a single selenocysteine, which is incorporated with low translational efficiency. The exception is selenoprotein P, which in some species is predicted to contain as many as 132 selenocysteines and which is considered to play roles in selenium transport and storage. Objective: This study aimed to develop comparative physiological and evolutionary perspectives on the function(s) of selenoprotein P. Method: The review of the literature on the roles of selenoprotein P in diverse animals. Results: Selenoprotein P contains multiple selenocysteines, making it energetically costly to produce. Furthermore, it is often associated with detrimental effects to the animals that produce it. Possible benefits that outweigh these costs include the general storage and transport of selenium; the transport of both toxic and useful metal ions; and specific functions in reproduction and in the nervous system. Conclusion: A probable reconciliation of the negative effects of producing Selenoprotein P is its benefit in terms of promoting reproductive success.



2014 ◽  
Vol 94 (5) ◽  
pp. 857-865 ◽  
Author(s):  
Kristen L. Deyman ◽  
Greta Chiu ◽  
Jingyun Liu ◽  
Carolyne J. Brikis ◽  
Christopher P. Trobacher ◽  
...  

Deyman, K. L., Chiu, G., Liu, J., Brikis, C. J., Trobacher, C. P., DeEll, J. R., Shelp, B. J. and Bozzo, G. G. 2014. Effects of elevated CO2 and 1-methylcyclopropene on storage-related disorders of Ontario-grown Empire apples. Can. J. Plant Sci. 94: 857–865. The impact of 1-methylcyclopropene (1-MCP) application on CO2-induced physiological injury in Empire apple fruit during controlled atmosphere storage was assessed over a 3-yr period using an experimental design involving multiple treatment replicates. Fruit harvested at optimal maturity from one or two orchards were treated with or without 1 µL L−1 1-MCP, then chilled at 0 or 3°C under various CO2 partial pressures (5, 2.5 or 0.03 kPa CO2) in the presence of 2.5 kPa O2 for up to 46 wk using a split-plot design. Fruit were sampled periodically for assessment of flesh browning and external peel injury. The maximal incidence of external CO2 injury varied from 15 to 100% over the 3 yr, and the most rapid development of this disorder was evident at 5 kPa CO2. The incidence of external CO2 injury as a function of storage time was influenced by orchard location and storage temperature. Moreover, the incidence of flesh browning at 0°C and 5 kPa CO2 was influenced slightly by orchard; this disorder was never higher than 30%, and the impact of elevated CO2 was inconsistent across years. Notably, there was no evidence for negative effects of 1-MCP on the incidence of storage-related disorders.



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