Effect of adding milk to black tea on vascular function in healthy men and women: a randomised controlled crossover trial

2018 ◽  
Vol 9 (12) ◽  
pp. 6307-6314 ◽  
Author(s):  
Adilah F. Ahmad ◽  
Lisa Rich ◽  
Henrietta Koch ◽  
Kevin D. Croft ◽  
Mario G. Ferruzzi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vascular Function ◽  
Crossover Trial ◽  
Black Tea ◽  
Tea Consumption ◽  
Short Term ◽  
Men And Women ◽  
Healthy Men ◽  
Randomised Controlled ◽  
P Addition

Addition of milk to black tea alters the acute/short-term benefical effect of regular black tea consumption on vascular function and blood pressure.

scholarly journals Short-Term Tea Consumption Is Not Associated with a Reduction in Blood Lipids or Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2020 ◽  
Vol 150 (12) ◽  
pp. 3269-3279
Author(s):  
Ebuwa Igho-Osagie ◽  
Kelly Cara ◽  
Deena Wang ◽  
Qisi Yao ◽  
Laura P Penkert ◽  
...  
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
At Risk ◽  
Ldl Cholesterol ◽  
Meta Analysis ◽  
Hdl Cholesterol ◽  
Black Tea ◽  
Tea Consumption ◽  
Short Term ◽  
High Quality

ABSTRACT Background A recent systematic review of epidemiological evidence suggests that higher amounts of tea intake are associated with lower risks of cardiovascular disease (CVD) incidence and mortality. Objectives Our study objective was to assess mechanisms by which tea consumption may influence CVD risks. Methods A systematic review and meta-analysis was conducted to investigate the effects of green and/or black tea consumption (≥4 wk) on systolic blood pressure (SBP), diastolic blood pressure (DBP), total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride (TG) in healthy populations and among at-risk adults (analyzed separately) with metabolic syndrome, prediabetes, and hypercholesterolemia. The Grading of Recommendations Assessment, Development and Evaluation approach was used to rate the strength of evidence (SoE). Results A total of 14 unique RCTs which randomly assigned 798 participants to either green tea, black tea, or placebo controls were included in our analyses. Intervention durations ranged from 4 to 24 wk (mean: 7.4 wk). Individual studies were judged as moderate to high quality based on risk of bias assessments. SoE was low to moderate owing to low sample sizes and insufficient power for most included studies to observe changes in the measured CVD biomarkers. Meta-analyses showed no significant effects of tea consumption on SBP, DBP, total cholesterol, LDL cholesterol, HDL cholesterol, and TG in healthy and at-risk adults (i.e., adults with obesity, prediabetes, borderline hypercholesterolemia, and metabolic syndrome). Conclusions Short-term (4–24 wk) tea consumption does not appear to significantly affect blood pressure or lipids in healthy or at-risk adults, although the evidence is limited by insufficient power to detect changes in these CVD biomarkers. High-quality RCTs with longer durations and sufficient sample sizes are needed to fully elucidate the effects of tea. This systematic review was registered at www.crd.york.ac.uk/prospero/ as CRD42020134513.

scholarly journals Short-term effects of polyphenol-rich black tea on blood pressure in men and women

2013 ◽  
Vol 4 (1) ◽  
pp. 111-115 ◽  
Author(s):  
Jonathan M. Hodgson ◽  
Richard J. Woodman ◽  
Ian B. Puddey ◽  
Theo Mulder ◽  
Dagmar Fuchs ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Black Tea ◽  
Short Term ◽  
Men And Women ◽  
Short Term Effects

Abstract P061: Effects of Black Tea With and Without a Fat Load on Vascular Function in Mildly Hypertensive Subjects

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Davide Grassi ◽  
Richard Draijer ◽  
Giovambattista Desideri ◽  
Theo Mulder ◽  
Claudio Ferri
Keyword(s):  
Blood Pressure ◽  
Endothelial Dysfunction ◽  
Endothelial Function ◽  
Vascular Function ◽  
Black Tea ◽  
Stiffness Index ◽  
Maximal Response ◽  
Tea Consumption ◽  
Double Blind ◽  
Reflection Index

Introduction: Endothelial dysfunction is an early biomarker for the development of cardiovascular disease and a predictor of future cardiovascular events. A number of intervention studies in healthy and diseased subjects have reported that endothelial function, as assessed by flow-mediated vasodilation (FMD), is positively affected by black tea consumption. On the other hand, high calorie fatty meals are detrimental to endothelial function. Hypothesis: To assess the effect of black tea with and without a fat load on FMD, digital volume pulse (DVP) and office blood pressure (BP) in never treated grade 1 hypertensive subjects without additional cardiovascular risk factors. Methods: According to a randomized, double-blind, controlled, cross-over design, 19 grade 1 hypertensives were assigned to consume black tea, containing 150 mg polyphenols or a placebo drink matched for caffeine, color and taste, twice a day for eight days, with a wash-out period in between of 13 days. On day 7 all measurements were performed in a fasted state, while on day 8 subjects consumed ultra-heat-treated whipping cream (1 gram fat per kg bodyweight) 30 minutes after consuming the test products. FMD, DVP and BP were measured at baseline and 1, 2, 3 and 4 hours after consumption of the test products. Results: Baseline FMD improved after 1-week tea consumption when compared to placebo (p<0.0001). An additional cup of tea further increased FMD at 1, 2, 3 and 4 hours after consumption when compared to baseline with maximal response 2 hours after intake (p<0.0001). Fat challenge significantly decreased FMD (p<0.0001), which was counteracted by tea consumption. Tea improved reflection index (small vessel tone; p<0.0001) and stiffness index (large arterial stiffness; p<0.0001) with additional effects after acute tea consumption with and without fat load. Further, tea decreased systolic and diastolic BP with and without a fat load (all p<0.0001). Conclusions: We demonstrate for the first time that moderate consumption of black tea protects against oral fat load-induced endothelial dysfunction in hypertensive but otherwise healthy subjects. The vascular benefits of tea are also reflected in improved endothelial function and peripheral arterial hemodynamics as well as blood pressure lowering under fasted and postprandial conditions. Our findings are of clinical relevance and interest, considering that the ingestion of the main daily meal has been suggested to be a trigger for acute myocardial infarction.

scholarly journals Age-Associated Changes in Blood Pressure in a Longitudinal Study of Healthy Men and Women

1997 ◽  
Vol 52A (3) ◽  
pp. M177-M183 ◽  
Author(s):  
J. D. Pearson ◽  
C. H. Morrell ◽  
L. J. Brant ◽  
P. K. Landis ◽  
J. L. Fleg
Keyword(s):  
Blood Pressure ◽  
Longitudinal Study ◽  
Men And Women ◽  
Healthy Men

Fibermalt is well tolerated in healthy men and women at intakes up to 60 g/d: a randomized, double-blind, crossover trial

2012 ◽  
Vol 64 (3) ◽  
pp. 274-281 ◽  
Author(s):  
Kevin C. Maki ◽  
Tia M. Rains ◽  
Kathleen M. Kelley ◽  
Chad M. Cook ◽  
Arianne L. Schild ◽  
...  
Keyword(s):  
Crossover Trial ◽  
Double Blind ◽  
Men And Women ◽  
Healthy Men

scholarly journals Cocoa flavanol intake improves endothelial function and Framingham Risk Score in healthy men and women: a randomised, controlled, double-masked trial: the Flaviola Health Study

2015 ◽  
Vol 114 (8) ◽  
pp. 1246-1255 ◽  
Author(s):  
Roberto Sansone ◽  
Ana Rodriguez-Mateos ◽  
Jan Heuel ◽  
David Falk ◽  
Dominik Schuler ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Pulse Wave Velocity ◽  
Endothelial Function ◽  
Cardiovascular Health ◽  
Framingham Risk Score ◽  
Pulse Wave ◽  
Men And Women ◽  
Framingham Risk ◽  
Randomised Controlled

AbstractCocoa flavanol (CF) intake improves endothelial function in patients with cardiovascular risk factors and disease. We investigated the effects of CF on surrogate markers of cardiovascular health in low risk, healthy, middle-aged individuals without history, signs or symptoms of CVD. In a 1-month, open-label, one-armed pilot study, bi-daily ingestion of 450 mg of CF led to a time-dependent increase in endothelial function (measured as flow-mediated vasodilation (FMD)) that plateaued after 2 weeks. Subsequently, in a randomised, controlled, double-masked, parallel-group dietary intervention trial (Clinicaltrials.gov: NCT01799005), 100 healthy, middle-aged (35–60 years) men and women consumed either the CF-containing drink (450 mg) or a nutrient-matched CF-free control bi-daily for 1 month. The primary end point was FMD. Secondary end points included plasma lipids and blood pressure, thus enabling the calculation of Framingham Risk Scores and pulse wave velocity. At 1 month, CF increased FMD over control by 1·2 % (95 % CI 1·0, 1·4 %). CF decreased systolic and diastolic blood pressure by 4·4 mmHg (95 % CI 7·9, 0·9 mmHg) and 3·9 mmHg (95 % CI 6·7, 0·9 mmHg), pulse wave velocity by 0·4 m/s (95 % CI 0·8, 0·04 m/s), total cholesterol by 0·20 mmol/l (95 % CI 0·39, 0·01 mmol/l) and LDL-cholesterol by 0·17 mmol/l (95 % CI 0·32, 0·02 mmol/l), whereas HDL-cholesterol increased by 0·10 mmol/l (95 % CI 0·04, 0·17 mmol/l). By applying the Framingham Risk Score, CF predicted a significant lowering of 10-year risk for CHD, myocardial infarction, CVD, death from CHD and CVD. In healthy individuals, regular CF intake improved accredited cardiovascular surrogates of cardiovascular risk, demonstrating that dietary flavanols have the potential to maintain cardiovascular health even in low-risk subjects.

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