Construction of a hypoxia responsive upconversion nanosensor for tumor imaging by fluorescence resonance energy transfer from carbon dots to ruthenium complex

2018 ◽  
Vol 6 (15) ◽  
pp. 2315-2322 ◽  
Author(s):  
Di Yang ◽  
Shanyue Guan ◽  
Yuefang Niu ◽  
Zheng Xie ◽  
Shuyun Zhou ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Fluorescence Resonance Energy Transfer ◽  
Carbon Dots ◽  
Tumor Imaging ◽  
Ruthenium Complex ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Nir Light ◽  
Phosphorescence Emission ◽  
Fluorescence Resonance

Hypoxia responsive upconversion nano-aggregates are synthesized which can be excited by NIR light to give oxygen dependent phosphorescence emission via the FRET process.

Fluorescence resonance energy transfer monitoring of pH-responsive doxorubicin release from carbon dots/aptamer functionalized magnetic mesoporous silica

Nanomedicine ◽  
2021 ◽  
Author(s):  
Abolghasem Abbasi Kajani ◽  
Masoud Ayatollahi Mehrgardi
Keyword(s):  
Drug Delivery ◽  
Energy Transfer ◽  
Fluorescence Resonance Energy Transfer ◽  
Carbon Dots ◽  
Drug Loading ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Spectroscopic Techniques ◽  
Ph Responsive ◽  
Fluorescence Resonance

Aim: To develop a novel theranostic nanoplatform for simultaneous fluorescent monitoring and stimuli-triggered drug delivery. Materials & methods: Different microscopic and spectroscopic techniques were used for the characterization of nanocarriers. MCF-7 and human umbilical vein endothelial cell lines were cultured and treated with different doses of doxorubicin-loaded nanocarriers. The cell viability and drug release were studied using MTT assay and fluorescence microscopy. Results: Biocompatible and mono-disperse nanocarriers represent hollow and mesoporous structures with the calculated surface area of 552.83 m2.g-1, high magnetic activity (12.6 emu.g-1), appropriate colloidal stability and high drug loading capacity (up to 61%). Conclusion: Taxane-based carbon dots act as the pH-responsive gatekeepers for the controlled release of doxorubicin into cancer cells and provide a fluorescence resonance energy transfer system for real-time monitoring of drug delivery.

Facile synthesis of fluorescent carbon dots for determination of curcumin based on fluorescence resonance energy transfer

RSC Advances ◽  
2015 ◽  
Vol 5 (79) ◽  
pp. 64790-64796 ◽  
Author(s):  
Ying Shi ◽  
Chunyan Li ◽  
Shaopu Liu ◽  
Zhongfang Liu ◽  
Jinghui Zhu ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Fluorescence Resonance Energy Transfer ◽  
Carbon Dots ◽  
Fluorescence Probe ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Facile Synthesis ◽  
Fluorescence Resonance ◽  
Fluorescent Carbon Dots

A carbon dot-based fluorescence probe was designed for detecting curcumin via fluorescence resonance energy transfer.

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