A graphene oxide coated gold nanostar based sensing platform for ultrasensitive electrochemical detection of circulating tumor DNA

2020 ◽  
Vol 12 (4) ◽  
pp. 440-447 ◽  
Author(s):  
Mahbubur Rahman ◽  
Daxiang Cui ◽  
Shukui Zhou ◽  
Amin Zhang ◽  
Di Chen

A high-performance electrochemical sensing platform inspired by a functional ‘green’ electrochemical reduction pathway was developed to identify and detect circulating tumor DNA (ctDNA) of gastric carcinoma in peripheral blood.

2021 ◽  
Author(s):  
Dongfei Chen ◽  
Yanfang Wu ◽  
Sharmin Hoque ◽  
Richard D. Tilley ◽  
J. Justin Gooding

This study introduces a new electrochemical sensing strategy for the rapid detection of circulating tumor DNA (ctDNA) from whole blood in combination with a network of DNA-Au@MNPs with high sensitivity and excellent selectivity.


RSC Advances ◽  
2015 ◽  
Vol 5 (121) ◽  
pp. 99669-99677 ◽  
Author(s):  
Junhua Li ◽  
Haibo Feng ◽  
Jianbo Jiang ◽  
Yonglan Feng ◽  
Zhifeng Xu ◽  
...  

We demonstrate that a new nanocomposite of CoFe2O4-reduced graphene oxide can be used as an enhanced electrochemical sensing platform for levodopa.


2021 ◽  
Vol 45 (6) ◽  
pp. 3215-3223
Author(s):  
Selvarasu Maheshwaran ◽  
Ramachandran Balaji ◽  
Shen-Ming Chen ◽  
Ray Biswadeep ◽  
Vengudusamy Renganathan ◽  
...  

A high-performance electrochemical sensing platform based on CuS nano-globules is efficiently developed.


2021 ◽  
Author(s):  
Feng Gao ◽  
Xiaolong Tu ◽  
Yongfang Yu ◽  
Yansha Gao ◽  
Jin Zou ◽  
...  

Abstract Herein, an efficient electrochemical sensing platform is proposed for selective and sensitive detection of nitrite on the basis of Cu@C@Zeolitic imidazolate framework-8 (Cu@C@ZIF-8) heterostructure. Core-shell Cu@C@ZIF-8 composite was synthesized by pyrolysis of Cu-metal-organic framework@ZIF-8 (Cu-MOF@ZIF-8) in Ar atmosphere on account of the difference of thermal stability between Cu-MOF and ZIF-8. For the sensing system of Cu@C@ZIF-8, ZIF-8 with proper pore size allows nitrite diffuse through the shell, while big molecules cannot, which ensures high selectivity of the sensor. On the other hand, Cu@C as electrocatalyst promotes the oxidation of nitrite, thereby resulting high sensitivity of the sensor. Accordingly, the Cu@C@ZIF-8 based sensor presents excellent performance for nitrite detection, which achieves a wide linear response range of 0.1 µM to 300.0 µM, and a low limit of detection (LOD) of 0.033 µM. In addition, the Cu@C@ZIF-8 sensor possesses excellent stability and reproducibility, and was employed to quantify nitrite in sausage samples with recoveries of 95.45-104.80%.


The Analyst ◽  
2016 ◽  
Vol 141 (13) ◽  
pp. 4074-4083 ◽  
Author(s):  
Zhonggang Liu ◽  
Heidi Forsyth ◽  
Neelam Khaper ◽  
Aicheng Chen

A high-performance electrochemical sensor with AuPt nanoparticles and reduced graphene oxide nanocomposites is demonstrated for the effective detection of NO.


2020 ◽  
Vol 8 (33) ◽  
pp. 7539-7547
Author(s):  
Xinrui Liu ◽  
Rajalakshmi Sakthivel ◽  
Yu-Cheng Chen ◽  
Ning Chang ◽  
Udesh Dhawan ◽  
...  

We have developed an electrochemical sensor based on integrated 2D materials including SnS2, graphene oxide, and β-cyclodextrin forming a ternary nanocomposite decorated on a screen-printed electrode for the electrochemical detection of melatonin.


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