A novel approach for the screening analysis of anticancer compounds from traditional Chinese medicine by a G-quadruplex functionalized magnetic system

2020 ◽  
Vol 12 (4) ◽  
pp. 528-534
Author(s):  
Yi Zhang ◽  
Jia Wu ◽  
Xiuxiu Liu ◽  
Hongxia Sun ◽  
Yin Chen ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Magnetic System ◽  
Screening System ◽  
Anticancer Compounds ◽  
Screening Analysis ◽  
Magnetic Screening ◽  
Novel Approach ◽  
System P ◽  
G Quadruplex ◽  
Anticancer Drug Discovery

G-quadruplex (G4) is a four-stranded DNA structure, viewed as an emerging therapeutic target in oncology. G4 coated magnetic screening system provides a feasible, easy-operating approach for anticancer drug discovery.

scholarly journals Efficient cleavage of tertiary amide bonds via radical–polar crossover using a copper(ii) bromide/Selectfluor hybrid system

2020 ◽  
Vol 11 (45) ◽  
pp. 12323-12328
Author(s):  
Zhe Wang ◽  
Akira Matsumoto ◽  
Keiji Maruoka
Keyword(s):  
Hybrid System ◽  
Amide Bonds ◽  
Tertiary Amide ◽  
Novel Approach ◽  
System P ◽  
Tertiary Amides

A novel approach for the efficient cleavage of the amide bonds in tertiary amides is reported.

Photocatalytic degradation of phenol by the heterogeneous Fe3O4 nanoparticles and oxalate complex system

RSC Advances ◽  
2014 ◽  
Vol 4 (77) ◽  
pp. 40828-40836 ◽  
Author(s):  
Piao Xu ◽  
Guangming Zeng ◽  
Danlian Huang ◽  
Liang Liu ◽  
Cui Lai ◽  
...  
Keyword(s):  
Complex System ◽  
Photocatalytic Degradation ◽  
Fe3o4 Nanoparticles ◽  
Radical Mechanism ◽  
Phenol Removal ◽  
Oxalate Complex ◽  
Novel Approach ◽  
System P

A novel approach for phenol removal using Fe3O4 nanoparticles and oxalate was proposed via a radical mechanism.

A Novel Approach for the Virtual Screening and Rational Design of Anticancer Compounds

2000 ◽  
Vol 43 (10) ◽  
pp. 1975-1985 ◽  
Author(s):  
Ernesto Estrada ◽  
Eugenio Uriarte ◽  
Alina Montero ◽  
Marta Teijeira ◽  
Lourdes Santana ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Rational Design ◽  
Anticancer Compounds ◽  
Novel Approach

Potassium-induced G-quadruplex DNAzyme as a chemiluminescent sensing platform for highly selective detection of K+

2014 ◽  
Vol 6 (18) ◽  
pp. 7415-7419 ◽  
Author(s):  
Hong Wang ◽  
Dong Mei Wang ◽  
Ming Xuan Gao ◽  
Jian Wang ◽  
Cheng Zhi Huang
Keyword(s):  
Reaction System ◽  
Selective Detection ◽  
Sensing Platform ◽  
System P ◽  
G Quadruplex

A simple and highly selective chemiluminescence (CL) method of K+ detection was firstly developed based on K+-sensitive G-qudruplex DNAzyme in luminol-H2O2 reaction system.

A novel approach based on OCT for tongue inspection in traditional Chinese medicine

2007 ◽  
Author(s):  
Haixin Dong ◽  
Zhouyi Guo ◽  
Changchun Zeng ◽  
Huiqing Zhong ◽  
Xin Gong ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Novel Approach ◽  
Tongue Inspection

Interaction of nano-quantum dots (CdSe@ZnS) and extracellular proteins in activated sludge revealed by bio-nano science

2020 ◽  
Vol 7 (9) ◽  
pp. 2795-2808
Author(s):  
Aibin Hu ◽  
Weijun Zhang ◽  
Guiying Liao ◽  
Dongsheng Wang ◽  
Yongzhen Peng
Keyword(s):  
Quantum Dots ◽  
Activated Sludge ◽  
Extracellular Proteins ◽  
Active Sludge ◽  
Novel Approach ◽  
System P ◽  
Nano Science ◽  
Insight Into

This work describes a novel approach for the purification of extracellular proteins (EP) from activated sludge, and provides an insight into the interaction between NPs and actual EP in the active sludge (AS) system.

Chiral Ru(ii) complexes act as a potential non-viral gene carrier for directional transportation to the nucleus and cytoplasm

Metallomics ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 504-513
Author(s):  
Qiong Wu ◽  
Shuang-Yan Zhang ◽  
Si-Yan Liao ◽  
Jie-Qiong Cao ◽  
Wen-Jie Zheng ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Self Assembly ◽  
The Self ◽  
Gene Carrier ◽  
Viral Gene ◽  
Carrier System ◽  
Quadruplex Dna ◽  
Novel Approach ◽  
G Quadruplex

A novel approach has been proposed to develop a potent gene carrier system for enantioselectivity on the self-assembly of G-quadruplex DNA promoted by chiral Ru(ii) complexes, and the different assembled nanostructures of cellular uptake to the nucleus and cytoplasm.

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