A revised analysis of current and emerging Nano suspension technological approaches for cardiovascular medicine

Background This is an objective critique to give an in-depth description of Nano suspensions. This article is attempting to address the issue of whether or not Nano science is realistic with respect to price, with regards to item costs being added to the endeavor and Lipotropic drugs have proven to be rewarding and Lipo-immunotherapy has proven to be beneficial. In modern times, drug marketing and promotion have become crucial to efficient commercializing of successful molecules, pharmaceutical companies often work to increase the chances of promoting successful drugs, these included cardiovascular drugs because of their widespread usage. Main body Nano suspension is a Nano metric Colloidal Suspension system i.e., Nano suspensions, in the solid form reaches the bloodstream and Nanoparticle colloids readily available to the target cells. All research on Nanostructures is focused on the four primary dimensions, composition, homogeneity, heterogeneity, elasticity, and agglomeration. Researchers are devising ways to deliver medication and other substances to a damaged cell and diseased region, as well as diagnose the body to pinpoint disease and defects, by way of Nanotechnology. Short conclusions The vital analysis of Nano science experiment on Nano suspension is working to achieve the goal of reducing product cost by using Nanotechnology in product development, as it wants to examine the probability of development by utilizing Nanotechnology. The usage of the top-limited technology allows the development of cardiovascular drugs classified under the biopharmaceutical classification system (Class II and Class IV) to use two approaches namely top-down and bottom-up methods.

Juice nanotechnology: A mini review

In the past two decades, nano-science is widely used in different applications and the increased interest in the utilization of nanoparticles in food processing is clear. Such applications include processing, packaging, development of functional food, safety, foodborne pathogens detection, and shelf-life extension. In this article, the essential facts and the latest uses of nano-science in fruit and vegetable juices were described. The green synthesis of nanoparticles with antioxidant, antibacterial and antifungal characteristics is of great interest in food preservation. These nanoparticles such as metals, oxidized metals and its bioactivity in juice were reviewed. The current procedures to prepare nanojuice including nanofiltration and the most recent nanomilling were presented. Beside the preparation, special emphasis has also been given to the chemical as well as the biological (microbial and enzymatic) quality of the produced nanojuice. The role of nanotechnology in the development of the smart and the active food packaging systems for the improvement of food shelf- life and quality was also discussed. Since the physical and chemical characteristics of nanoparticles are completely different from those of macro-size. Therefore, special and urgent attention by responsible authorities should be given and effective policies should be applied for food products to ensure product quality, customer health and safety as well as the environmental protection.

Cosmeceuticals and Nanotechnology in Beauty Care Products

New technologies are booming in personal care industry. Nowadays, Cosmeceuticals as well as Nanotechnology are the favorite areas of interest in cosmetic industries. Cosmetic industry are updating and improving rapidly by implementing new trends and technologies. The term Cosmeceuticals was first coined in 1984 by Albert Kligman. The word Cosmeceuticals is fusion of cosmetics and pharmaceuticals. It means they possess combination of cosmetic and pharmaceutical properties. In simple words cosmecuticals are applied topically as cosmetics but as we know that they contain pharmaceutical properties too so they affect the skin's biological function. In last 2 to 3 decades cosmeceutical market is booming in the cosmetic as well as pharmaceutical industries. Every person wants to look beautiful and use of cosmeceuticals is the current trend to beautify your outer look. Now cosmeceuticals is considered as one of the fastest growing segment of the natural personal care industry. The use of cosmeceuticals has radically scaled in last decades. Some new advancement and technologies are entering in this cosmetic industries i.e. nanotechnology. Since last few decades, the nanotechnology has been acquired importance in numerous areas of science. Nano science has grown greatly, reason behind that is nanomaterials have extensive applications in material science, engineering, and medicine. Nanocosmetics are over taking the new cosmeceutical market. Nanocarriers are used to deliver cosmecutical ingredients topically. Hence this review tries to understand the basic information of cosmeceuticals, nanocosmeticsand some other related advancement in cosmetic industry. The difference between drug, cosmetics, cosmeceuticals, nanocosmetics, is also considered in this article. This paper also aims to highlight the beauty care industry and tries to comprehensive information of cosmeceuticals and nanotechnology used in cosmetic industry.

Synthesis and Characterization of Pectin Beads for the Smart Delivery of Agrochemicals

Aim: The study was conducted to design pectin beads for achieving slow release of agrochemicals in wetlands via ion gelation method. Place and Duration of the Study: The laboratory experiment was carried out at the Department of Nano Science & Technology, Tamil Nadu Agricultural University, Tamil Nadu during March-July 2021. Methodology: Pectin beads were synthesized varying the concentrations of pectin (4, 6, 8, and 10 per cent) and calcium chloride (CaCl2) concentrations (0.5, 1, and 2 per cent). Calcium pectinate beads of different combinations were synthesized via ion gelation method. Calcium pectinate beads were characterized based on the recovery yield of beads, while surface characterization was done through Scanning electron microscope (SEM) and optical microscope to understand the topography of beads and assess the size of the beads respectively. Pore volume and surface area were also studied using BET (Brunauer-Emmett-Teller) analyzer. Results: The yield of calcium pectinate beads were higher while using the concentration of pectin @ 4 per cent and CaCl2 @ 2 per cent as cross-linking agent. The spherical and smooth surface of beads was achieved with the concentrations of 6 and 2 per cent pectin and CaCl2 respectively, while beads were flat and smooth with concentration of pectin @ 4 per cent. Similarly, complete solubility of pectin was not achieved with concentrations of 8 and 10 per cent. BET results of beads showed that beads are non-porous in nature. Conclusion: Pectin and CaCl2 concentrations @ 6 and 2 per cent respectively were found to be ideal for the delivery of agrochemical based on the yield and surface morphology.

Preface

The 2021 International Conference on Advanced Materials and Mechatronics (ICAMM 2021) was planned to be held on October 30 - November 1, 2021 in Kunming, China. Currently, the entire world is struggling against the virulent pandemic COVID-19. Unfortunately, each of us is affected, either overtly or covertly. Our conference, 2021 International Conference on Advanced Materials and Mechatronics (ICAMM 2021) was not an exception. The ICAMM 2021 was changed to be held online through Zoom software. This approach not only reduces people gathering, but also meets their communication needs. Nowadays, the research and development level and industrialization scale of advanced materials have become an important symbol to measure the economic and social development, scientific and technological progress and national defense strength of a country or region. Compared with the traditional mechanical manufacturing, the composite mechanical and electronic engineering and its technology with the introduction of artificial intelligence technology have a greater application prospect, and can meet the needs of increasingly complex industrial production and manufacturing in the era of highly developed industrial capacity. Advanced materials and mechanical and electronic mutual integration, mutual promotion, the penetration of relevant research and results affect the development of various fields in China, which is of great significance to accelerate China’s social upgrading and transformation and seize the commanding heights of a new round of scientific and technological revolution. The purpose of the conference is to build a bridge of communication for experts, scholars and personnel from all walks of life in the field of materials and electromechanics, and to help and promote the intersection and integration of different disciplines. We were greatly honored to have invited Prof.Wenhui Ma, Kunming University of Science and Technology, China and Prof. Yuanchang Zhong, Chongqing University, China to serve as our Conference Chairman. There were over 105 participants attended the meeting. During the conference, the conference model was divided into three sessions, including oral presentations, keynote speeches, and online Q&A discussion. In the first part, some scholars, whose submissions were selected as the excellent papers, were given about 5-10 minutes to perform their oral presentations one by one. Then in the second part, keynote speakers were each allocated 30-45 minutes to hold their speeches. In the second part, we invited three professors as our keynote speakers. The first one, Prof. Weidong Zhu, from University of Maryland. His research spans the fields of dynamics, vibration, control, applied mechanics, structural health monitoring, metamaterials, and wind energy, and involves analytical development, numerical simulation, experimental validation, and industrial application. Prof. Junxi Bi, Inner Mongolia University of Technology as our second keynote speaker. Prof. Xinyong Li, from Dalian University of Technology. His mainly research interests: energy catalysis, nano catalysis, green catalysis, nano science and engineering, chemistry and biosensor. Their insightful speeches had triggered heated discussion in the third session of the conference. Every participant praised this conference for disseminating useful and insightful knowledge. The proceedings of ICAMM 2021 span over 6 topical tracks, that include: Mechanics of materials, Structural mechanics, Mechanics, dynamics and its applications, Irradiation electronics, Optical/electronic/magnetic materials and other related fields. All the papers have been through rigorous review and process to meet the requirements of International publication standard. We would like to acknowledge all of those who have supported ICAMM 2021. Each individual and institutional help were very important for the success of this conference. Especially we would like to thank the organizing committee for their valuable advices in the organization and helpful peer review of the papers. The Committee of ICAMM 2021 List of Committee member are available in this pdf.

Applications of Carbon Based Materials in Developing Advanced Energy Storage Devices

With the increasing pressure of population, the energy demand is growing explosively. By 2050, it is expected that the world population may reach to about 9 billion which may result in the increase of energy requirement to about 12.5 trillion watts. Due to increasing pressures of population, industries and technology, concerns to find possibilities to cope with increasing demand of energy resources, arise. Although the renewable energy resources including fossil fuels, wind, water and solar energy have been used for a long time to fulfill the energy requirements, but they need efficient conversions and storage techniques and are responsible for causing environmental pollution due to greenhouse gases as well. It is thus noteworthy to develop methods for the generation and storage of renewable energy devices that can replace the conventional energy resources to meet the requirement of energy consumption. Due to high energy demands, the sustainable energy storage devices have remained the subject of interest for scientists in the history, however, the traditional methods are not efficient enough to fulfill the energy requirements. In the present era, among other variety of advanced treatments, nano-sciences have attracted the attention of the scientists. While talking about nano-science, one cannot move on without admiring the extraordinary features of carbon nanotubes (CNTs) and other carbon based materials. CNTs are on the cutting edge of nano science research and finding enormous applications in energy storage devices. Excellent adsorption capabilities, high surface area, better electrical conductivity, high mechanical strength, corrosion resistance, high aspect ratio and good chemical and physical properties of CNTs have grabbed tremendous attention worldwide. Their charge transfer properties make them favorable for energy conversion applications. The limitation to the laboratory research on CNTs for energy storage techniques due to low specific capacitance and limited electrochemical performance can be overcome by surface functionalization using surface functional groups that can enhance their electrical and dispersion properties. In this chapter, ways CNTs employed to boost the abilities of the existing material used to store and transfer of energy have been discussed critically. Moreover, how anisotropic properties of CNTs play important role in increasing the energy storage capabilities of functional materials. It will also be discussed how various kinds of materials can be combined along CNTs to get better results.

Development of Amino Acids Functionalized SBA-15 for the Improvement of Protein Adsorption

Ordered mesoporous materials and their modification with multiple functional groups are of wide scientific interest for many applications involving interaction with biological systems and biomolecules (e.g., catalysis, separation, sensor design, nano-science or drug delivery). In particular, the immobilization of enzymes onto solid supports is highly attractive for industry and synthetic chemistry, as it allows the development of stable and cheap biocatalysts. In this context, we developed novel silylated amino acid derivatives (Si-AA-NH2) that have been immobilized onto SBA-15 materials in biocompatible conditions avoiding the use of toxic catalyst, solvents or reagents. The resulting amino acid-functionalized materials (SBA-15@AA) were characterized by XRD, TGA, EA, Zeta potential, nitrogen sorption and FT-IR. Differences of the physical properties (e.g., charges) were observed while the structural ones remained unchanged. The adsorption of the enzyme lysozyme (Lyz) onto the resulting functionalized SBA-15@AA materials was evaluated at different pHs. The presence of different functional groups compared with bare SBA-15 showed better adsorption results, for example, 79.6 nmol of Lyz adsorbed per m2 of SBA-15@Tyr compared with the 44.9 nmol/m2 of the bare SBA-15.

Organoid Technology: A Reliable Developmental Biology Tool for Organ-Specific Nanotoxicity Evaluation

Engineered nanomaterials are bestowed with certain inherent physicochemical properties unlike their parent materials, rendering them suitable for the multifaceted needs of state-of-the-art biomedical, and pharmaceutical applications. The log-phase development of nano-science along with improved “bench to beside” conversion carries an enhanced probability of human exposure with numerous nanoparticles. Thus, toxicity assessment of these novel nanoscale materials holds a key to ensuring the safety aspects or else the global biome will certainly face a debacle. The toxicity may span from health hazards due to direct exposure to indirect means through food chain contamination or environmental pollution, even causing genotoxicity. Multiple ways of nanotoxicity evaluation include several in vitro and in vivo methods, with in vitro methods occupying the bulk of the “experimental space.” The underlying reason may be multiple, but ethical constraints in in vivo animal experiments are a significant one. Two-dimensional (2D) monoculture is undoubtedly the most exploited in vitro method providing advantages in terms of cost-effectiveness, high throughput, and reproducibility. However, it often fails to mimic a tissue or organ which possesses a defined three-dimensional structure (3D) along with intercellular communication machinery. Instead, microtissues such as spheroids or organoids having a precise 3D architecture and proximate in vivo tissue-like behavior can provide a more realistic evaluation than 2D monocultures. Recent developments in microfluidics and bioreactor-based organoid synthesis have eased the difficulties to prosper nano-toxicological analysis in organoid models surpassing the obstacle of ethical issues. The present review will enlighten applications of organoids in nanotoxicological evaluation, their advantages, and prospects toward securing commonplace nano-interventions.