A smartphone-based fiber-optic aptasensor for label-free detection of Plasmodium falciparum glutamate dehydrogenase

2020 ◽  
Vol 12 (10) ◽  
pp. 1333-1341
Author(s):  
Manoharan Sanjay ◽  
Naveen K. Singh ◽  
Lightson Ngashangva ◽  
Pranab Goswami

A novel smartphone-based, multi-channel, optic fiber platform for quantitative detection of Plasmodium falciparum glutamate dehydrogenase (PfGDH) has been explored in this study.

ACS Sensors ◽  
2021 ◽  
Author(s):  
Pallavi Halkare ◽  
Nirmal Punjabi ◽  
Jigme Wangchuk ◽  
Santhosh Madugula ◽  
Kiran Kondabagil ◽  
...  

Sensors ◽  
2019 ◽  
Vol 19 (13) ◽  
pp. 2857 ◽  
Author(s):  
Jin-Ho Park ◽  
Gyuho Yeom ◽  
Donggu Hong ◽  
Eun-Jung Jo ◽  
Chin-Ju Park ◽  
...  

A simple and rapid As3+ detection method using 3-nitro-L-tyrosine (N-Tyr) is reported. We discovered the specific property of N-Tyr, which specifically chelates As3+. The reaction between As3+ and N-Tyr induces a prompt color change to vivid yellow, concomitantly increasing the absorbance at 430 nm. The selectivity for As3+ is confirmed by competitive binding experiments with various metal ions (Hg2+, Pb2+, Cd2+, Cr3+, Mg2+, Ni2+, Cu2+, Fe2+, Ca2+, Zn2+, and Mn2+). Also, the N-Tyr binding site, binding affinity, and As3+/N-Tyr reaction stoichiometry are investigated. The specific reaction is utilized to design a sensor that enables the quantitative detection of As3+ in the 0.1–100 μM range with good linearity (R2 = 0.995). Furthermore, the method’s applicability for the analysis of real samples, e.g., tap and river water, is successfully confirmed, with good recoveries (94.32–109.15%) using As3+-spiked real water samples. We believe that our discovering and its application for As3+ analysis can be effectively utilized in environmental analyses such as those conducted in water management facilities, with simplicity, rapidity, and ease.


2015 ◽  
Author(s):  
M. I. Zibaii ◽  
H. Latifi ◽  
A. Asadollahi ◽  
A. H. Bayat ◽  
A. Haghparast

The Analyst ◽  
2017 ◽  
Vol 142 (11) ◽  
pp. 1974-1981 ◽  
Author(s):  
Savannah Kaye ◽  
Zheng Zeng ◽  
Mollye Sanders ◽  
Krishnan Chittur ◽  
Paula M. Koelle ◽  
...  

A miniaturized, robust, localized surface plasmon resonance (LSPR)–coupled fiber-optic (FO) nanoprobe providing an integrated and portable solution for detection of DNA hybridization and measurement of DNA concentrations has been demonstrated.


2011 ◽  
Vol 26 (7) ◽  
pp. 3367-3370 ◽  
Author(s):  
Reshma Bharadwaj ◽  
V.V.R. Sai ◽  
Kamini Thakare ◽  
Arvind Dhawangale ◽  
Tapanendu Kundu ◽  
...  

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