Open-air preparation of cross-linked CO2-responsive polymer vesicles by enzyme-assisted photoinitiated polymerization-induced self-assembly

2019 ◽  
Vol 55 (79) ◽  
pp. 11920-11923 ◽  
Author(s):  
Liangliang Yu ◽  
Yuxuan Zhang ◽  
Xiaocong Dai ◽  
Qin Xu ◽  
Li Zhang ◽  
...  
Keyword(s):  
Self Assembly ◽  
High Solids ◽  
Photoinitiated Polymerization ◽  
Polymer Vesicles ◽  
Responsive Polymer

An open-air strategy via enzyme-assisted photoinitiated polymerization-induced self-assembly (photo-PISA) in water is developed for preparing cross-linked CO2-responsive vesicles at high solids contents.

Facile Preparation of CO2 -Responsive Polymer Nano-Objects via Aqueous Photoinitiated Polymerization-Induced Self-Assembly (Photo-PISA)

2016 ◽  
Vol 38 (13) ◽  
pp. 1600508 ◽  
Author(s):  
Jianbo Tan ◽  
Xuechao Zhang ◽  
Dongdong Liu ◽  
Yuhao Bai ◽  
Chundong Huang ◽  
...  
Keyword(s):  
Self Assembly ◽  
Photoinitiated Polymerization ◽  
Responsive Polymer ◽  
Facile Preparation

scholarly journals H2S gasotransmitter-responsive polymer vesicles

2016 ◽  
Vol 7 (3) ◽  
pp. 2100-2105 ◽  
Author(s):  
Qiang Yan ◽  
Wei Sang
Keyword(s):  
Drug Delivery ◽  
Hydrogen Sulfide ◽  
Cell Signaling ◽  
Diblock Copolymer ◽  
Targeted Drug Delivery ◽  
Self Assembly ◽  
Signaling Molecule ◽  
Polymer Vesicles ◽  
Responsive Polymer ◽  
Targeted Drug

A type of new polymeric vesicle self-assembly byo-azidomethylbenzoate-containing diblock copolymer can respond to the cell signaling molecule hydrogen sulfide (H2S). The intracellular H2S gasotransmitter can trigger biomimetic polymersome disruption for targeted drug delivery.

Flow Chemistry Controls Both Self-Assembly and the Entrapped Oscillatory Cargo in Belousov-Zhabotinsky Driven Polymerization-Induced Self-Assembly

2019 ◽  
Author(s):  
Liman Hou ◽  
Marta Dueñas-Diez ◽  
Rohit Srivastava ◽  
Juan Perez-Mercader
Keyword(s):  
Self Assembly ◽  
Flow Chemistry ◽  
Batch Reactors ◽  
Equilibrium Conditions ◽  
One Pot ◽  
Bz Reaction ◽  
Polymer Vesicles ◽  
Simultaneous Control ◽  
Novel Method ◽  
Continuously Stirred Tank Reactor

<p></p><p>Belousov-Zhabotinsky (B-Z) reaction driven polymerization-induced self-assembly (PISA), or B-Z PISA, is a novel method for the autonomous one-pot synthesis of polymer vesicles from a macroCTA (macro chain transfer agent) and monomer solution (“soup”) containing the above and the BZ reaction components. In it, the polymerization is driven (and controlled) by periodically generated radicals generated in the oscillations of the B-Z reaction. These are inhibitor/activator radicals for the polymerization. Until now B-Z PISA has only been carried out in batch reactors. In this manuscript we present the results of running the system using a continuously stirred tank reactor (CSTR) configuration which offers some interesting advantages.Indeed, by controlling the CSTR parameters we achieve reproducible and simultaneous control of the PISA process and of the properties of the oscillatory cargo encapsulated in the resulting vesicles. Furthermore, the use of flow chemistry enables a more precise morphology control and chemical cargo tuning. Finally, in the context of biomimetic applications a CSTR operation mimics more closely the open non-equilibrium conditions of living systems and their surrounding environments.</p><p></p>

Stimuli-responsive polymer vesicles

Soft Matter ◽  
2009 ◽  
Vol 5 (5) ◽  
pp. 927 ◽  
Author(s):  
Min-Hui Li ◽  
Patrick Keller
Keyword(s):  
Stimuli Responsive ◽  
Polymer Vesicles ◽  
Responsive Polymer ◽  
Stimuli Responsive Polymer

Chemically Responsive Polymer Inverse-Opal Photonic Crystal Films Created by a Self-Assembly Method

2016 ◽  
Vol 120 (22) ◽  
pp. 11938-11946 ◽  
Author(s):  
Huilin Zhao ◽  
Jianping Gao ◽  
Zeng Pan ◽  
Guanbo Huang ◽  
Xiaoyang Xu ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Self Assembly ◽  
Inverse Opal ◽  
Assembly Method ◽  
Responsive Polymer ◽  
Crystal Films

On-demand shape transformation of polymer vesicles via site-specific isomerization of hydrazone photoswitches in monodisperse hydrophobic oligomers

2021 ◽  
Author(s):  
Valene Wang ◽  
Jiwon Kim ◽  
Junyoung Kim ◽  
Seul Woo Lee ◽  
Kyoung Taek Kim
Keyword(s):  
Drug Delivery ◽  
Block Copolymers ◽  
Conformational Change ◽  
Self Assembly ◽  
Shape Control ◽  
Shape Transformation ◽  
Site Specific ◽  
On Demand ◽  
Polymer Vesicles

The shape control of nanostructures formed by the solution self-assembly of block copolymers is of significance for drug delivery. In particular, site-specific perturbation resulting in the conformational change of the...

Hyperbranched polymer vesicles: from self-assembly, characterization, mechanisms, and properties to applications

2015 ◽  
Vol 44 (12) ◽  
pp. 3874-3889 ◽  
Author(s):  
Wenfeng Jiang ◽  
Yongfeng Zhou ◽  
Deyue Yan
Keyword(s):  
Self Assembly ◽  
Hyperbranched Polymer ◽  
Polymer Vesicles

This tutorial review summarizes the first 10 years of work on hyperbranched polymer vesicles from syntheses, self-assembly, and properties to applications.

scholarly journals PhotoATRP Induced Self-Assembly (PhotoATR-PISA) Enables Simplified Synthesis of Responsive Polymer Nanoparticles in One-Pot

2020 ◽  
Author(s):  
Ali Shahrokhinia ◽  
Randall Scanga ◽  
Priyanka Biswas ◽  
James Reuther
Keyword(s):  
Self Assembly ◽  
Glycidyl Methacrylate ◽  
Uv Light ◽  
Copper Catalyst ◽  
Crosslinking Agent ◽  
Polymer Nanoparticles ◽  
One Pot ◽  
Responsive Polymer ◽  
Catalyst Systems ◽  
First Time

<p><b>ABSTRACT:</b> Photo-controlled atom transfer radical polymerization (PhotoATRP) was implemented, for the first time, to accomplish polymerization induced self-assembly (PISA) mediated by UV light (λ = 365 nm) using ppm levels (ca. < 20 ppm) of copper catalyst at ambient temperature. Using Cu<sup>II</sup>Br<sub>2</sub>/tris(pyridin-2-ylmethyl)amine (TPMA) catalyst systems, PISA was per-formed all in one-pot starting from synthesis of solvophilic poly(oligo(ethylene oxide) methyl ether methacrylate) (POEGMA) blocks to core-crosslinked nanoparticles (NPs) utilizing poly(glycidyl methacrylate) (PGMA) and N,N-cystamine bismethacrylamide (CBMA) as the solvophobic copolymer and crosslinking agent, respectively. Sequential chain-extensions were performed for PGMA demonstrating capabilities for accessing multi-block copolymers with temporal control via switching the UV light on and off. Further, core-crosslinking of PISA nanoparticles was performed via the slow incorporation of the CBMA enabling one-pot crosslinking during the PISA process. Finally, the disulfide installed in the CBMA core-crosslinks allowed for the stimuli-triggered dissociation of nanoparticles using DL-dithiothreitol at acidic pH.</p>

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