Potentiating bisphosphonate-based coordination complexes to treat osteolytic metastases

The phase-inversion hydrothermal synthesis of alendronate and Ca(ii) promotes the formation of a coordination complex whose solid-state, stability, particle size and cytotoxicity were assessed and optimized to potentiate its biomedical applications.

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Solid-State Coordination Chemistry: Hydrothermal Synthesis of Layered Vanadium Oxides with Interlayer Metal Coordination Complexes

Angewandte Chemie International Edition in English ◽

10.1002/anie.199609891 ◽

1996 ◽

Vol 35 (9) ◽

pp. 989-991 ◽

Cited By ~ 104

Author(s):

Yiping Zhang ◽

Jeffrey R. D. DeBord ◽

Charles J. O'Connor ◽

Robert C. Haushalter ◽

Abraham Clearfield ◽

...

Keyword(s):

Coordination Chemistry ◽

Hydrothermal Synthesis ◽

Solid State ◽

Coordination Complexes ◽

Vanadium Oxides ◽

Metal Coordination ◽

State Coordination

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Hydrothermal Synthesis and Solid-State Laser Refrigeration of Ytterbium-Doped Potassium Lutetium Fluoride (KLF) Microcrystals

10.26434/chemrxiv.12330737.v3 ◽

2020 ◽

Author(s):

Xiaojing Xia ◽

Anupum Pant ◽

Xuezhe Zhou ◽

Elena Dobretsova ◽

Alex Bard ◽

...

Keyword(s):

Hydrothermal Synthesis ◽

Solid State ◽

Information Science ◽

Point Group ◽

Solid State Laser ◽

Lanthanide Ions ◽

Group Symmetry ◽

Luminescence Spectra ◽

Crystalline Phases ◽

State Laser

Fluoride crystals, due to their low phonon energies, are attractive hosts of trivalent lanthanide ions for applications in upconverting phosphors, quantum information science, and solid-state laser refrigeration. In this article, we report the rapid, low-cost hydrothermal synthesis of potassium lutetium fluoride (KLF) microcrystals for applications in solid-state laser refrigeration. Four crystalline phases were synthesized, namely orthorhombic K2LuF5 (Pnma), trigonal KLuF4 (P3121), orthorhombic KLu2F7 (Pna21), and cubic KLu3F10 (Fm3m), with each phase exhibiting unique microcrystalline morphologies. Luminescence spectra and emission lifetimes of the four crystalline phases were characterized based on the point-group symmetry of trivalent cations. Laser refrigeration was measured by observing both the optomechanical eigenfrequencies of microcrystals on cantilevers in vacuum, and also the Brownian dynamics of optically trapped microcrystals in water. Among all four crystalline phases, the most significant cooling was observed for 10%Yb:KLuF4 with cooling of 8.6 $\pm$ 2.1 K below room temperature. Reduced heating was observed with 10%Yb:K2LuF5

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Preparation of LiMn0.4Fe0.6PO4/C Composite by A New Route Combining Solid-state Reaction with Hydrothermal Synthesis

Journal of Inorganic Materials ◽

10.3724/sp.j.1077.2014.13672 ◽

2014 ◽

Cited By ~ 1

Author(s):

Jian LI ◽

Shu-Heng YAO ◽

Hong-Ming ZHOU ◽

Wen-Jun GENG

Keyword(s):

Hydrothermal Synthesis ◽

Solid State ◽

Solid State Reaction

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Unravelling the dissolution mechanism of polyphosphate glasses by 31P NMR spectroscopy: ligand competition and reactivity of intermediate complexes

Dalton Transactions ◽

10.1039/d0dt03381b ◽

2021 ◽

Author(s):

Dahiana Andrea Avila Salazar ◽

Peter Bellstedt ◽

Atsuhiro Miura ◽

Yuki Oi ◽

Toshihiro Kasuga ◽

...

Keyword(s):

Nuclear Magnetic Resonance ◽

Solid State ◽

Nmr Spectroscopy ◽

Biomedical Applications ◽

Structural Changes ◽

31P Nmr ◽

Dissolution Mechanism ◽

31P Nmr Spectroscopy ◽

Glass Dissolution ◽

Polyphosphate Glasses

Phosphate glass dissolution can be tailored via compositional and subsequent structural changes, which is of interest for biomedical applications such as therapeutic ion delivery. Here, solid-state 31P nuclear magnetic resonance...

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Preparation of Ginger Oil in Water Nanoemulsion Using Phase Inversion Composition Technique: Effects of Stirring and Water Addition Rates on their Physico-Chemical Properties and Stability

Zeitschrift für Physikalische Chemie ◽

10.1515/zpch-2019-1427 ◽

2019 ◽

Vol 0 (0) ◽

Author(s):

Ashraf Farshbaf-Sadigh ◽

Hoda Jafarizadeh-Malmiri ◽

Navideh Anarjan ◽

Yahya Najian

Keyword(s):

Particle Size ◽

Phase Inversion ◽

Antimicrobial Properties ◽

Chemical Properties ◽

Water Addition ◽

Chromatography Method ◽

Stirring Rate ◽

Physico Chemical ◽

Oil In Water ◽

Addition Rate

Abstract Ginger oil in water (O/W) nanoemulsions, were produced using phase inversion composition method and Tween 80, as emulsifier. Effects of processing parameters namely, stirring rate (100 to1000 rpm) and water addition rate (1–10 mL/min) were evaluated on the physico-chemical, morphological, antioxidant and antimicrobial properties of the prepared O/W nanoemulsions using response surface methodology (RSM). Results indicated that well dispersed and spherical ginger nanodroplets were formed in the nanoemulsions with minimum particle size (8.80 nm) and polydispersity index (PDI, 0.285) and maximum zeta potential value (−9.15 mV), using stirring rate and water addition rate of 736 rpm and 8.18 mL/min, respectively. Insignificant differences between predicted and experimental values of the response variables, indicated suitability of fitted models using RSM. Mean particle size of the prepared nanoemulsion using optimum conditions were changed from 8.81 ± 1 to 9.80 ± 1 nm, during 4 weeks of storage, which revealed high stability of the resulted ginger O/W nanoemulsion. High antioxidant activity (55.4%), bactericidal (against Streptococcus mutans) and fungicidal (against Aspergillus niger) activities of the prepared nanoemulsion could be related to the presence of gingerols and shogaols, a group of phenolic alkanones, in the ginger oil, which those were detected by gas chromatography method.

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Sol-Gel Synthesis of the Double Perovskite Sr2FeMoO6 by Microwave Technique

Materials ◽

10.3390/ma14143876 ◽

2021 ◽

Vol 14 (14) ◽

pp. 3876

Author(s):

Jesús Valdés ◽

Daniel Reséndiz ◽

Ángeles Cuán ◽

Rufino Nava ◽

Bertha Aguilar ◽

...

Keyword(s):

Particle Size ◽

Hydrothermal Synthesis ◽

Microwave Radiation ◽

Structural Characteristics ◽

Sol Gel ◽

Synthesis Method ◽

Double Perovskite ◽

Synthesis Methods ◽

X Ray ◽

Sol Gel Synthesis

The effect of microwave radiation on the hydrothermal synthesis of the double perovskite Sr2FeMoO6 has been studied based on a comparison of the particle size and structural characteristics of products from both methods. A temperature, pressure, and pH condition screening was performed, and the most representative results of these are herein presented and discussed. Radiation of microwaves in the hydrothermal synthesis method led to a decrease in crystallite size, which is an effect from the reaction temperature. The particle size ranged from 378 to 318 nm when pH was 4.5 and pressure was kept under 40 bars. According to X-ray diffraction (XRD) results coupled with the size-strain plot method, the product obtained by both synthesis methods (with and without microwave radiation) have similar crystal purity. The Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray Spectroscopy (EDS) techniques showed that the morphology and the distribution of metal ions are uniform. The Curie temperature obtained by thermogravimetric analysis indicates that, in the presence of microwaves, the value was higher with respect to traditional synthesis from 335 K to 342.5 K. Consequently, microwave radiation enhances the diffusion and nucleation process of ionic precursors during the synthesis, which promotes a uniform heating in the reaction mixture leading to a reduction in the particle size, but keeping good crystallinity of the double perovskite. Precursor phases and the final purity of the Sr2FeMoO6 powder can be controlled via hydrothermal microwave heating on the first stages of the Sol-Gel method.

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