Association between dietary fatty acid patterns based on principal component analysis and fatty acid compositions of serum and breast milk in lactating mothers in Nanjing, China

2021 ◽  
Author(s):  
Ye Ding ◽  
Yue Yang ◽  
Fangping Xu ◽  
Mei Ye ◽  
Ping Hu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Principal Component Analysis ◽  
Fatty Acid ◽  
Breast Milk ◽  
Principal Component ◽  
Maternal Serum ◽  
Dietary Fatty Acids ◽  
Lactating Mothers ◽  
Fatty Acid Patterns ◽  
Fatty Acid Compositions

This study aimed to comprehensively analyze dietary fatty acids (FAs) to evaluate their association with FA compositions of maternal serum and breast milk and assess their effects on mothers and...

scholarly journals Association between dietary fatty acids pattern and incidence of oral cancer: A case-control study from Southeast China

2021 ◽  
Author(s):  
Yi Fan ◽  
Yu Qiu ◽  
Qing Chen ◽  
Sijie Wang ◽  
Mingming Xu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Oral Cancer ◽  
Saturated Fatty Acids ◽  
Fatty Acid Pattern ◽  
Principal Component ◽  
Dietary Fatty Acids ◽  
Control Group ◽  
Oral Cancer Patients ◽  
Fatty Acid Patterns

Abstract ObjectiveTo investigate the relationship between dietary fatty acid pattern and the risk of oral cancer (OC).MethodIn 446 patients with primary oral cancer and 448 controls, we assessed prediagnosis consumption of 159 food items by food frequency questionnaires completed within 1 week of diagnosis. Fatty acid patterns were identified using principal component analysis. Odds ratio (OR) and 95% confidence (CI) interval was calculated.ResultsGeneral differences of fatty acid intake were observed between case and control, intake of saturated fatty acids such as C14:0, C16:0, C18:0 are higher in case than control group (p < 0.001), intake of monounsaturated fatty acid such as C18:1 is higher in case than control group (p < 0.001). We identified a fatty acid pattern which was characterized by saturated fatty acids and it explained 33.2% of the overall variability of the 32 fatty acids. The identified fatty acid pattern scores were positively associated with a higher risk of oral cancer [multivariable-adjusted OR comparing extreme quintiles, 3.325 (95%CI: 2.222, 4.975); Ptrend<0.001].ConclusionsGeneral differences of dietary fatty acids were observed between oral cancer patients and controls. A dietary fatty acids pattern, which was mainly composed of saturated fatty acids were positively correlated with the risk of oral cancer.

scholarly journals Dietary Fatty Acids and Host–Microbial Crosstalk in Neonatal Enteric Infection

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2064 ◽  
Author(s):  
Candice Quin ◽  
Deanna L. Gibson
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Breast Milk ◽  
Acid Composition ◽  
Disease Susceptibility ◽  
Dietary Fatty Acids ◽  
Enteric Infection ◽  
Human Breast Milk ◽  
Human Breast

Human milk is the best nutritional choice for infants. However, in instances where breastfeeding is not possible, infant formulas are used as alternatives. While formula manufacturers attempt to mimic the performance of human breast milk, formula-fed babies consistently have higher incidences of infection from diarrheal diseases than those breastfed. Differences in disease susceptibility, progression and severity can be attributed, in part, to nutritional fatty acid differences between breast milk and formula. Despite advances in our understanding of breast milk properties, formulas still present major differences in their fatty acid composition when compared to human breast milk. In this review, we highlight the role of distinct types of dietary fatty acids in modulating host inflammation, both directly and through the microbiome-immune nexus. We present evidence that dietary fatty acids influence enteric disease susceptibility and therefore, altering the fatty acid composition in formula may be a potential strategy to improve infectious outcomes in formula-fed infants.

Effects of Different Dietary Fatty Acids on the Fatty Acid Compositions and the Expression of Lipid Metabolic-Related Genes in Mammary Tumor Tissues of Rats

2008 ◽  
Vol 60 (6) ◽  
pp. 810-825 ◽  
Author(s):  
Na Wei ◽  
Bin Wang ◽  
Qian-Yong Zhang ◽  
Man-Tian Mi ◽  
Jun-Dong Zhu ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Mammary Tumor ◽  
Dietary Fatty Acids ◽  
Tumor Tissues ◽  
Fatty Acid Compositions

scholarly journals Genes and Dietary Fatty Acids in Regulation of Fatty Acid Composition of Plasma and Erythrocyte Membranes

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1785 ◽  
Author(s):  
Maria Lankinen ◽  
Matti Uusitupa ◽  
Ursula Schwab
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Cell Membranes ◽  
Dietary Fatty Acids ◽  
Erythrocyte Membranes ◽  
Extensive Literature ◽  
Chromosome 11 ◽  
Fatty Acid Compositions

The fatty acid compositions of plasma lipids and cell membranes of certain tissues are modified by dietary fatty acid composition. Furthermore, many other factors (age, sex, ethnicity, health status, genes, and gene × diet interactions) affect the fatty acid composition of cell membranes or plasma lipid compartments. Therefore, it is of great importance to understand the complexity of mechanisms that may modify fatty acid compositions of plasma or tissues. We carried out an extensive literature survey of gene × diet interaction in the regulation of fatty acid compositions. Most of the related studies have been observational studies, but there are also a few intervention trials that tend to confirm that true interactions exist. Most of the studies deal with the desaturase enzyme cluster (FADS1, FADS2) in chromosome 11 and elongase enzymes. We expect that new genetic variants are being found that are linked with the genetic regulation of plasma or tissue fatty acid composition. This information is of great help to understanding the contribution of dietary fatty acids and their endogenic metabolism to the development of some chronic diseases.

scholarly journals Positive relationship between consumption of specific fish type and n-3 PUFA in milk of Hong Kong lactating mothers

2019 ◽  
Vol 121 (12) ◽  
pp. 1431-1440
Author(s):  
Vincy Wing-Si Wong ◽  
Yuk-Fan Ng ◽  
Suk-Mei Chan ◽  
Yi-Xiang Su ◽  
Kevin Wing-Hin Kwok ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Hong Kong ◽  
Fatty Acid ◽  
Breast Milk ◽  
Fatty Acid Profile ◽  
Dietary Factors ◽  
Dietary Intakes ◽  
Lactating Women ◽  
Lactating Mothers ◽  
Dietary Record

AbstractResidents of Hong Kong have undergone a dietary transition from a traditional Chinese diet that is high in seafood to a more Western diet. This may have affected the nutritional composition of breast milk of Hong Kong mothers. The present study aims to investigate the relationship between the dietary pattern and the fatty acid profile of the breast milk of lactating women in Hong Kong. Seventy-three volunteering healthy Hong Kong lactating mothers participated in the study. Their dietary intakes were assessed by using a 3-d dietary record and FFQ. The mean n-3 fatty acid levels were approximately 0·4 % (EPA) and 0·9 % (DHA) of total fatty acids in the breast milk of lactating mothers who had exclusively breastfed their infants aged 2–6 months. Maternal dietary intakes of n-3 fatty acids were positively associated with their levels in the breast milk. The levels of maternal intakes of freshwater and saltwater fish, especially the consumption of salmon, croaker and mandarin, were significantly correlated with the content of DHA in breast milk. The present study is among the very few in the literature to determine the fatty acid profile of breast milk in Hong Kong populations and verify certain dietary factors that influence this profile. High levels of n-3 PUFA, especially DHA, were observed in the breast milk of Hong Kong lactating women. The findings may serve as a dietary reference for lactating mothers to optimise the fatty acid profile of their breast milk.

SIMCA principal component analysis of fatty acid patterns in Day-1 and Day-8 cod (Gadus morhua) and haddock (Melanogrammus aeglefinus) eggs

1986 ◽  
Vol 92 (2) ◽  
pp. 173-182 ◽  
Author(s):  
N. B. Vogt ◽  
E. Moksness ◽  
S. P. Sporst�l ◽  
H. Knutsen ◽  
S. Nordenson ◽  
...  
Keyword(s):  
Principal Component Analysis ◽  
Fatty Acid ◽  
Gadus Morhua ◽  
Principal Component ◽  
Component Analysis ◽  
Melanogrammus Aeglefinus ◽  
Fatty Acid Patterns ◽  
Haddock Melanogrammus Aeglefinus

scholarly journals Effect of dietary fatty acids on serum parameters, fatty acid compositions, and liver histology in Shaoxing laying ducks

2011 ◽  
Vol 12 (9) ◽  
pp. 736-743 ◽  
Author(s):  
Wei-meng Liu ◽  
Shu-jing Lai ◽  
Li-zhi Lu ◽  
Fang-xiong Shi ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Dietary Fatty Acids ◽  
Liver Histology ◽  
Serum Parameters ◽  
Fatty Acid Compositions

scholarly journals Analisis Asam Lemak Daging Anjing pada Bakso Sapi Menggunakan Gas Chromatography Mass Spectrometry (GCMS) yang Dikombinasikan dengan PCA (Principal Component Analysis)

2018 ◽  
Vol 1 (2) ◽  
pp. 117
Author(s):  
Irfan Nugraha ◽  
Pri Iswati Utami ◽  
Wiranti Sri Rahayu
Keyword(s):  
Mass Spectrometry ◽  
Fatty Acids ◽  
Principal Component Analysis ◽  
Fatty Acid ◽  
Qualitative Analysis ◽  
Principal Component ◽  
Caproic Acid ◽  
Eicosatrienoic Acid ◽  
Rapid Screening ◽  
Gas Chromatography Mass Spectrometry

ABSTRAKTingginya perbedaan harga daging, membuat beberapa penjual yang tidak etis mengganti daging sapi dengan daging anjing secara sengaja untuk mendapatkan keuntungan ekonomis. Tujuan dilakukan penelitian ini adalah untuk mengetahui kemampuan GCMS yang dikombinasi dengan kemometrika PCA untuk analisis cepat dari asam lemak anjing pada bakso formulasi dan bakso sapi di pasaran. Metode penelitian ini adalah non eksperimental berupa identifikasi profil asam lemak daging anjing  pada bakso sapi formulasi dan bakso sapi di pasaran. Hasil penelitian yang didapat berupa profil kromatogram GCMS menunjukkan bahwa terdapat perbedaan komposisi asam lemak antara daging anjing dan sapi. Pada lemak daging anjing muncul beberapa asam lemak yang tidak dimiliki oleh lemak daging sapi diantaranya asam kaproat, asam siklopentanetridekanoat, asam arakhidonat, asam 7,10,13- eikosatrienoat, asam 9,12,15- oktadekatrienoat. Analisis kualitatif dari kromatogram GCMS menggunakan PCA menunjukkan lemak sapi, anjing, kambing, babi dan ayam dapat diidentifikasi dan dibedakan. Analisis kualitatif kandungan lemak anjing dalam bakso sapi formulasi menunjukkan perbedaan antara bakso formulasi yang memiliki kedekatan mirip dengan lemak sapi serta yang mirip dengan lemak anjing. Analisis kualitatif lemak anjing pada bakso sapi di pasaran menunjukkan sampel tidak mengandung lemak anjing.Kata kunci : bakso, GCMS, lemak daging anjingABSTRACTDue to the high difference of meat price, some unethical seller replaces beef intentionally with dog meat to get economical profits. The objective of this study is to assess the capability of GCMS coupled with chemometrics of PCA for rapid screening of dog fat in beef meatball formulation and beef meatballs in the market. The method of this research is non experimental that is identification of fatty acid profile of dog meat in beef meatball simulation and beef meatballs in the market. The result obtained from GCMS chromatogram profile showed that there is a difference in fatty acid composition between beef and dog meat. In dog meat fat appears some fatty acids that are not owned by beef fat i.e caproic acid, cyclopentanetridecanoic acid, arachidonate acid, 7,10,13-eicosatrienoic acid, 9,12,15-octadecatrienoic acid. Qualitative analysis from GCMS chromatogram using PCA showed that beef, dog, goat, pork and chicken can be identified and differentiated. Qualitative analysis of dog fat in simulated beef meatballs showed difference between simulated meatballs that have similar proximity to beef's fat as well as those that are similar to dog fat. Qualitative analysis of dog fat in beef meatballs in the market showed the sample doesn't contain dog fat. Keywords : dog meat fat, GCMS, meatball

scholarly journals Seed fatty acid compositions and chemotaxonomy of wild Crambe (Brassicaceae) taxa in Turkey

2020 ◽  
Vol 44 (6) ◽  
pp. 662-670
Author(s):  
İlhan SUBAŞI
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Principal Component ◽  
Molecular Cluster ◽  
Nervonic Acid ◽  
Flora Of Turkey ◽  
Seed Fatty Acid ◽  
Natural Flora ◽  
Species Groups ◽  
Fatty Acid Compositions

Wild Crambe species have greater potential than Crambe hispanica in industry, medicine, as a vegetable, etc. A total of 53 germplasm accessions, belonging to 7 taxa, were collected from the natural flora of Turkey. The accessions consisted of C. orientalisvar. orientalis (18 accessions), C. orientalis var. dasycarpa (1 accession), C. orientalis var. sulphurea (2 accessions), C.tataria var. aspera(3 accessions), C. tataria var. tataria (26 accessions), C. grandiflora (1 accession), C. orientalis var. sulphurea, and C. maritima (2 accessions). In this study, the seed fatty acid compositions and oil contents were determined, and the data were used for taxonomic cluster, correlation, and principal component analyses. Important correlations were determined among the fatty acids; however, the oil contents were not correlated. Altitude was positively correlated with linolenic acid, while negatively correlated with oleic and linoleic acid. For the principal component and correlation analyses, 7 major fatty acids (>1%) were used, including palmitic (C16:0), oleic (C18:1), linoleic (C18:2), cis-11 eicosenoic (20:1), linolenic (C18:3), erucic (C22:1), and nervonic acid (C24:1). A total of 17 fatty acids were used for the cluster analyses. Two major clusters were formed, where the first consisted of C. orientalis, C. tataria, and C. grandiflorataxa, while the second consisted of only C. maritima taxa. The dendrogram based on the fatty acid values clearly discriminated the species groups; however, C. tataria was not located close to C. maritima, contrary to previous molecular cluster studies.

scholarly journals Fatty Acid Composition of Juniperus Species (Juniperus Section) Native to Turkey

2012 ◽  
Vol 7 (7) ◽  
pp. 1934578X1200700 ◽  
Author(s):  
Ayşegül Güvenç ◽  
Nurgün Küçükboyacι ◽  
Ahmet Ceyhan Gören
Keyword(s):  
Mass Spectrometry ◽  
Fatty Acids ◽  
Gas Chromatography ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Gas Chromatography Mass Spectrometry ◽  
Seed Oils ◽  
Juniperonic Acid ◽  
Fatty Acid Patterns ◽  
Fatty Acid Compositions

Fatty acid compositions of seeds of five taxa of the Juniperus section of the genus Juniperus L. (Cupressaceae), i. e. J. drupacea Lab., J. communis L. var. communis, J. communis var. saxatilis Pall., J. oxycedrus L. subsp. oxycedrus, and J. oxycedrus subsp. macrocarpa (Sibth. & Sm.) Ball, were investigated. Methyl ester derivatized fatty acids of the lipophylic extracts of the five species were comparatively analyzed by capillary gas chromatography-mass spectrometry (GC-MS). Juniperus taxa showed uniform fatty acid patterns, among which linoleic (25.8–32.5%), pinolenic (11.9–24.1%) and oleic acids (12.4–17.2%) were determined to be the main fractions in the seed oils. Juniperonic acid was found to be remarkably high in J. communis var. saxatilis (11.4 %), J. oxycedrus subsp. oxycedrus (10.4 %), and J. communis var. communis (10.1 %). To the best of our knowledge, the present work discloses the first report on the fatty acid compositions of seeds of this Juniperus section grown in Turkey.

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