Current advances on drug delivery nanoparticles for respiratory diseases treatment

Author(s):  
Beatriz Rossi Canuto de Menezes ◽  
Karla Faquine Faquine Rodrigues ◽  
Vanessa Modelski Schatkoski ◽  
Raíssa Monteiro Pereira ◽  
Renata Guimarães Ribas ◽  
...  

Cases of respiratory diseases have been growing around the world, affecting the health and life quality of millions of people every year. Chronic respiratory diseases (CRDs) and acute respiratory infections...

2022 ◽  
pp. 225-233
Author(s):  
L. S. Starostina

The problem of respiratory diseases and their therapy options still retains much of its urgency. Respiratory diseases in children are still super common. According to the data on infectious morbidity among children in the Russian Federation for the period 2018–2020, current trends have not changed, and the acute respiratory infections (ARI) are still ranked number one in terms of the frequency of registered diseases. According to the official records, the frequency of ARI in children among infectious diseases is 71,850.02 per 100,000 population, or 71%. Such well-known symptom as cough is one of the most frequent manifestations of respiratory diseases. It causes the greatest discomfort for both the little patients and their parents, the quality of life of the children and those around them worsens, many domestic and foreign authors mention this symptom in their works. And it is this problem that doctors of various specialties most often face. The cough is currently treated with drugs with different effects depending on the characteristics and manifestations of the disease. Systematic reviews and multicenter studies show that prescription of mucoactive drugs to treat cough in children with underlying ARI is substantiated and feasible. The authors substantiated the necessity of using combinations of various drugs aimed to reduce inflammation of the airways, improve mucociliary clearance, thin out and promote sputum discharge and, accordingly, reduce cough. The article briefly discusses the mechanisms of the development of cough in ARI, the action of drug substances included in the combination drugs used to treat cough in children, the possibility of using the combination of muco- and bronchoactive drugs of synthetic and plant origin.


1994 ◽  
Vol 23 ◽  
pp. S66-S67
Author(s):  
C.A.J. Ketelaars ◽  
H.Abu Saad ◽  
R.J.G. Halfens ◽  
R. Mostert ◽  
M.A.G. Schlosser ◽  
...  

Nanomedicine ◽  
2021 ◽  
Author(s):  
Ankur Sharma ◽  
Dhruv Kumar ◽  
Kajal Dahiya ◽  
Susan Hawthorne ◽  
Saurabh Kumar Jha ◽  
...  

The increasing burden of respiratory diseases caused by microbial infections poses an immense threat to global health. This review focuses on the various types of biofilms that affect the respiratory system and cause pulmonary infections, specifically bacterial biofilms. The article also sheds light on the current strategies employed for the treatment of such pulmonary infection-causing biofilms. The potential of nanocarriers as an effective treatment modality for pulmonary infections is discussed, along with the challenges faced during treatment and the measures that may be implemented to overcome these. Understanding the primary approaches of treatment against biofilm infection and applications of drug-delivery systems that employ nanoparticle-based approaches in the disruption of biofilms are of utmost interest which may guide scientists to explore the vistas of biofilm research while determining suitable treatment modalities for pulmonary respiratory infections.


2020 ◽  
Vol 4 (11) ◽  
pp. 698-704
Author(s):  
E.S. Dzottsoeva ◽  
◽  
A.V. Gorelov ◽  
◽  

Acute respiratory infections (ARIs) in children are common conditions characterized by high morbidity. ARIs account for up to 75% of all cases of antibiotic use. Dysbiosis results in the impaired performance of vital functions, i.e., digestion, synthesis, colonization resistance, and the regulation of immune system. Probiotics are one of the effective tools to affect the composition of gut microbiota and to restore its metabolic activity. Probiotics, their effects on human organism, and their use in various diseases have received an enormous attention. Meanwhile, the use of antibiotics and the etiological diversity of ARIs account for the lack and irrationality of extensive preventive measures (as in flu) and raise the interest in non-specific prophylaxis. Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subsp. Lactis BB-12 are well-studied strains. Lactobacillus plantarum LP01 and LP02, Lactobacillus rhamnosus LR04 and LR05, and Bifidobacterium lactis BS01 used as monostrain probiotics are also of interest. Multistrain probiotics are gaining traction. However, these probiotics are understudied and require more attention. KEYWORDS: microbiome, monostrain probiotics, multistrain probiotics, acute respiratory infections, antibiotic-associated diarrhea, antibiotic-associated syndrome, Lactobacillus rhamnosus, Bifidobacterium lactis. FOR CITATION: Dzottsoeva E.S., Gorelov A.V. Monostrain and multistrain probiotics for respiratory diseases in children. Russian Medical Inquiry. 2020;4(11):698–704. DOI: 10.32364/2587-6821-2020-4-11-698-704.


2013 ◽  
Vol 2 (1) ◽  
pp. 17-34
Author(s):  
Sari Viciawati Machdum

Zakah in Indonesia has a great potential in contributing the improvement of life quality of people in need in Indonesia. With this such potential, many Amil Zakah Institutions (Lembaga Amil Zakat/LAZ) are founded in Indonesia as faith based organizations (FBO). The literatures mentioned that Faith Based Organization has already taken its own place in the world of Social Work and Social Welfare. This article discussed the LAZ existence as one of the FBO in Indonesia. Utilization of zakah from charity to empowerment--including economic empowerment—has been an evidence that LAZ evolved into a better direction. This certainly can negate the negative stigma that has been pinned to social services of the FBO. Keywords: faith based organization, human service organization, manajemen, lembaga amil zakat


2020 ◽  
Vol 81 (4) ◽  
pp. 419-436 ◽  
Author(s):  
Dinesh K. Chellappan ◽  
Lim W. Yee ◽  
Kong Y. Xuan ◽  
Kishen Kunalan ◽  
Lim C. Rou ◽  
...  

2013 ◽  
Vol 187 (1) ◽  
pp. 114-117 ◽  
Author(s):  
Donata Kurpas ◽  
Bozena Mroczek ◽  
Helena Knap-Czechowska ◽  
Dorota Bielska ◽  
Aneta Nitsch-Osuch ◽  
...  

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