scholarly journals Monostrain and multistrain probiotics for respiratory diseases in children

2020 ◽  
Vol 4 (11) ◽  
pp. 698-704
Author(s):  
E.S. Dzottsoeva ◽  
◽  
A.V. Gorelov ◽  
◽  
Keyword(s):  
Respiratory Diseases ◽  
Respiratory Infections ◽  
Lactobacillus Rhamnosus ◽  
Human Organism ◽  
High Morbidity ◽  
Acute Respiratory Infections ◽  
Bifidobacterium Lactis ◽  
Impaired Performance ◽  
Vital Functions ◽  
Multistrain Probiotics

Acute respiratory infections (ARIs) in children are common conditions characterized by high morbidity. ARIs account for up to 75% of all cases of antibiotic use. Dysbiosis results in the impaired performance of vital functions, i.e., digestion, synthesis, colonization resistance, and the regulation of immune system. Probiotics are one of the effective tools to affect the composition of gut microbiota and to restore its metabolic activity. Probiotics, their effects on human organism, and their use in various diseases have received an enormous attention. Meanwhile, the use of antibiotics and the etiological diversity of ARIs account for the lack and irrationality of extensive preventive measures (as in flu) and raise the interest in non-specific prophylaxis. Lactobacillus rhamnosus GG (LGG) and Bifidobacterium animalis subsp. Lactis BB-12 are well-studied strains. Lactobacillus plantarum LP01 and LP02, Lactobacillus rhamnosus LR04 and LR05, and Bifidobacterium lactis BS01 used as monostrain probiotics are also of interest. Multistrain probiotics are gaining traction. However, these probiotics are understudied and require more attention. KEYWORDS: microbiome, monostrain probiotics, multistrain probiotics, acute respiratory infections, antibiotic-associated diarrhea, antibiotic-associated syndrome, Lactobacillus rhamnosus, Bifidobacterium lactis. FOR CITATION: Dzottsoeva E.S., Gorelov A.V. Monostrain and multistrain probiotics for respiratory diseases in children. Russian Medical Inquiry. 2020;4(11):698–704. DOI: 10.32364/2587-6821-2020-4-11-698-704.

Newer Virus Diseases: Clinical Differentiation of Acute Respiratory Infections

PEDIATRICS ◽  
1961 ◽  
Vol 27 (1) ◽  
pp. 44-44
Author(s):  
DAVID T. KARZON
Keyword(s):  
Respiratory Diseases ◽  
Small Volume ◽  
Respiratory Infections ◽  
Daily Practice ◽  
Clinical Aspects ◽  
Acute Respiratory Infections ◽  
Viral Etiology ◽  
Virus Diseases ◽  
Acute Respiratory Diseases ◽  
Basic Concepts

Acute respiratory diseases, especially those of viral etiology, occupy a goodly proportion of the attention of the pediatrician in his daily practice. In this small volume, Dr. Adams attempts to bring together the rapidly appearing information regarding recent discoveries and innovations in virology and correlate them with clinical aspects of respiratory infection. Sections are devoted to introducing basic concepts in virology and to anatomic and physiologic aspects of the respiratory system in relation to infection.

scholarly journals The herbal preparations in the treatment of cough in children with respiratory infections

2019 ◽  
pp. 82-86 ◽  
Author(s):  
V. М. Deliagin
Keyword(s):  
Herbal Medicine ◽  
Respiratory Diseases ◽  
Respiratory Infections ◽  
Symptomatic Treatment ◽  
Common Symptom ◽  
Acute Respiratory Infections ◽  
It Use ◽  
Herbal Preparations ◽  
Outpatient Practice ◽  
Common Infection

Acute respiratory infections (ARI, commen cold) are the most common infection diseases in children. They account for up 75% of all cases of respiratory diseases. In most cases, ARI are selfterminating diseases that require only symptomatic treatment. The most common symptom of ARI is cough. In outpatient practice justified the use of herbal medicine. As an antisussive well eastablished syrup Gedelix. The effectivnesses of the medicine, the possibility of accuracy dosing, pleasant taste facilitate it use in children.

scholarly journals The place of combined mucoactive drugs in the treatment of acute respiratory infections in children

2022 ◽  
pp. 225-233
Author(s):  
L. S. Starostina
Keyword(s):  
Respiratory Diseases ◽  
Respiratory Infections ◽  
Acute Respiratory Infections ◽  
Multicenter Studies ◽  
Current Trends ◽  
Drug Substances ◽  
Combination Drugs ◽  
The Russian Federation ◽  
Official Records

The problem of respiratory diseases and their therapy options still retains much of its urgency. Respiratory diseases in children are still super common. According to the data on infectious morbidity among children in the Russian Federation for the period 2018–2020, current trends have not changed, and the acute respiratory infections (ARI) are still ranked number one in terms of the frequency of registered diseases. According to the official records, the frequency of ARI in children among infectious diseases is 71,850.02 per 100,000 population, or 71%. Such well-known symptom as cough is one of the most frequent manifestations of respiratory diseases. It causes the greatest discomfort for both the little patients and their parents, the quality of life of the children and those around them worsens, many domestic and foreign authors mention this symptom in their works. And it is this problem that doctors of various specialties most often face. The cough is currently treated with drugs with different effects depending on the characteristics and manifestations of the disease. Systematic reviews and multicenter studies show that prescription of mucoactive drugs to treat cough in children with underlying ARI is substantiated and feasible. The authors substantiated the necessity of using combinations of various drugs aimed to reduce inflammation of the airways, improve mucociliary clearance, thin out and promote sputum discharge and, accordingly, reduce cough. The article briefly discusses the mechanisms of the development of cough in ARI, the action of drug substances included in the combination drugs used to treat cough in children, the possibility of using the combination of muco- and bronchoactive drugs of synthetic and plant origin.

scholarly journals Acute respiratory diseases: progression features, pharmaceutical therapy

2018 ◽  
pp. 82-88
Author(s):  
N. V. Orlova ◽  
T. G. Suranova
Keyword(s):  
Respiratory Diseases ◽  
Respiratory Infections ◽  
Intracellular Bacteria ◽  
Acute Respiratory Infections ◽  
Pharmaceutical Therapy ◽  
Wide Range ◽  
Acute Respiratory Diseases ◽  
High Concentrations ◽  
Acute Respiratory Viral Infection ◽  
Social Importance

Acute respiratory diseases (ARD) are widespread diseases and are of great social importance. Diagnosis of acute respiratory infections implies the damage to the respiratory system caused by a wide range of pathogens. Among the pathogens of acute respiratory infections are viruses of acute respiratory viral infection (ARVI) group, including influenza, as well as fungal and bacterial pathogens, which include intracellular bacteria: mycoplasma and chlamydia. Diseases caused by intracellular pathogens are treated by antibacterial drugs that can easily penetrate the cells and create there high concentrations.

Coronavirus Disease 2019 (COVID-19) and Cardiovascular Disease: A Vicious Circle

2020 ◽  
Author(s):  
Francesco Vetta
Keyword(s):  
Cardiovascular Diseases ◽  
Respiratory Infections ◽  
Close Association ◽  
Human Mobility ◽  
Mortality Rates ◽  
High Morbidity ◽  
Acute Respiratory Infections ◽  
Pharmacological Interactions ◽  
Severe Acute Respiratory Infections ◽  
Short Time

Over the last two decades, we have witnessed major epidemics of severe acute respiratory infections that pose a serious threat to global health, with high morbidity and mortality rates. The more widespread and faster human mobility by modern transports, allowing quick international connections, has contributed to the fast spread of epidemics, leading, as in the case of Coronavirus Disease 2019 (COVID-19), to a pandemic state in a short time. The first literature data show high COVID-19 infectivity, with a marked respiratory tropism, and a mortality rate ranging between 2 and 8% in different countries, in relation to people affected different mean age and comorbidity. In fact, in COVID-19 patients a close association between mortality, age and comorbidity have been demonstrated. Pre-existing cardiovascular diseases are widely represented in these patients and are associated with a poorer prognosis. Moreover, this virus has also shown a specific tropism towards the cardiovascular system, showing itself responsible for a series of severe acute and chronic diseases. Because of the frequent association with cardiovascular diseases, it is important to keep in mind the principal pharmacological interactions between cardiovascular drugs and those commonly used for the treatment of COVID-19 patients. Finally, given the complexity of these patients and their comorbidities, it seems essential to propose the establishment of a multi-specialist COVID-Team.

scholarly journals Fenspiride use in acute respiratory infections in children

2019 ◽  
pp. 120-123
Author(s):  
N. G. Kolosova ◽  
M. D. Shakhnazarova
Keyword(s):  
Safety Profile ◽  
Respiratory Diseases ◽  
Respiratory Infections ◽  
Economic Problem ◽  
Acute Respiratory Infections ◽  
Efficacy And Safety ◽  
High Efficacy ◽  
Acute Respiratory Diseases ◽  
Anti Inflammatory

Acute respiratory infections are the most common pathology in childhood, representing not only a medical but also a socio-economic problem. Numerous studies on the use of anti-inflammatory therapy in ARI have shown high efficacy and safety profile of fenspiride. The combination of anti-inflammatory, antiallergic, and antispasmodic properties ensures the success of fenspiride in the treatment of acute respiratory diseases in children. Fenspiride reduces symptoms of ARI, accelerates recovery, reduces the need for additional prescription of other drugs.

scholarly journals Study of risk factors of acute respiratory infections in children admitted in a tertiary care hospital of Southern Maharashtra

2017 ◽  
Vol 4 (9) ◽  
pp. 3129
Author(s):  
Alka C. Kaware ◽  
Nitin H. Kamble ◽  
S. K. Mangulikar
Keyword(s):  
Risk Factors ◽  
Respiratory Infections ◽  
Tertiary Care ◽  
High Morbidity ◽  
Acute Respiratory Infections ◽  
Care Hospital ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
History Of ◽  
Tract Infections

Background: Acute respiratory infections (ARI) is an important cause of mortality and morbidity in children. In India, it constitutes 15% of under five deaths. Various risk factors are responsible for ARI in children. Study of risk factors will help to reduce the high morbidity and mortality due to ARI. The objectives were to study risk factors responsible for acute respiratory infections in children and to find out case fatality rate &/ outcome of acute respiratory infections ARI in children.Methods: A hospital based cross sectional study was done in 2013-14 in a tertiary care centre to study the risk factors associated with ARI in children. All the pediatric patients between 0-12 years admitted in a tertiary care centre at Solapur were enrolled in the study.Results: Acute respiratory tract infections (ARI) were more common in 1-4 years age group i.e. 57.31% (196). It was more common in males i.e. 64.33% (220) than females i.e. 35.67% (122). ARI was more common in lower socio-economic classes i.e. class V (50.58%), class IV (22.52%); in patients whose mothers were illiterate 43.28% and who had history of parental smoking 84.21%. Maximum patients of ARI were having history of overcrowding 75.73%, inadequate cross-ventilation 81.87% and use of smoky chullah 78.65% in their home. Statistically significant association found between ARI cases and these socio-demographic factors. 46.78% (160) were incompletely immunized and 16.37% (56) were not immunized at all. Only 36.84% (126) were completely immunized for their age. Maximum cases of ARI (50.88%) occurred in winter season followed by rainy season (26.90%). Outcome showed that 91.52% (313) were cured, while 1.75% (6) patients died due to ARI.Conclusions: The present study has identified various socio-demographic, nutritional and environmental risk factors for ARI which can be prevented by effective health education and an appropriate initiative taken by the government.

scholarly journals Epidemiologic pattern of respiratory diseases among hospitalized pediatric patients in Khulna, Bangladesh

2021 ◽  
Vol 7 (6) ◽  
pp. 306
Author(s):  
M. Mirajul Islam ◽  
Joy Debnath ◽  
Nadira Naznin Rakhi ◽  
Abdullah Al-Jubayer
Keyword(s):  
Respiratory Diseases ◽  
Pediatric Patients ◽  
Respiratory Infections ◽  
Risk Group ◽  
National Level ◽  
Age Groups ◽  
Hospitalization Rate ◽  
Acute Respiratory Infections ◽  
High Burden ◽  
Interpretative Approach

<p class="abstract"><strong>Background:</strong> High burden of acute respiratory infections (ARIs) with a significant rate of mortality is notable in developing countries including Bangladesh. Despite the frequent reports of ARIs, the exact prevalence and spectrum of ARIs in this country is unknown even at subnational level. The aim of the study was to determine of current spectrum of respiratory diseases of children in Bangladesh.</p><p class="abstract"><strong>Methods:</strong> The current study analyzed 2993 pediatric patients admitted form June 2019 to January 2020 into Khulna Shishu Hospital, Khulna, Bangladesh using a quantitative interpretative approach.  </p><p class="abstract"><strong>Results:</strong> A total of 1382 patients (46.17%) were admitted because of ARIs and were predominately male children (65.77%). Among different ARIs, hospitalization was mainly due to lower tract respiratory infections (LRTI) and the prevalent cases of ARIs could be classified into undifferentiated ARI (20.92%), pneumonia (14.84%) and LRTI other than pneumonia and bronchitis (9.02%), bronchitis (1.40%). Mortality rate was observed 2.51%, although the highest rate of mortality (65%) was recorded among the infant age groups.</p><p class="abstract"><strong>Conclusions:</strong> This study showed the risk group and risk factors of developing severity in ARIs leading to a high hospitalization rate due to ARIs among children in Bangladesh. More such studies at national level are required to develop proper combating strategy to decrease the mortality and the morbidity associated with ARIs in the country.</p>

scholarly journals THE CURRENT SITUATION OF MOTHERS’ KNOWLEDGE OF CARING FOR CHILDREN UNDER 5 YEARS OLD WITH ACUTE RESPIRATORY INFECTIONS AT THAI BINH CHILDREN’S HOSPITAL IN 2020

2020 ◽  
Vol 62 (1) ◽  
Author(s):  
Thị Hảo Tăng ◽  
Thị Hải Tăng
Keyword(s):  
Health Workers ◽  
Respiratory Infections ◽  
Intervention Group ◽  
Morbidity And Mortality ◽  
Average Score ◽  
Control Group ◽  
High Morbidity ◽  
Acute Respiratory Infections ◽  
Current State ◽  
Children Under 5

Acute respiratory infections currently have high morbidity and mortality rates, are the leading cause of the burden of disease and the 3rd leading cause of death in children under 5 years old. The care, management and prevention of acute respiratory infections not only depend on health workers, but also on mother’s knowledge. Mothers have good knowledge about diseases, care plays an important role in disease prevention, early detection and timely delivery of children to health facilities, helping to reduce the infant morbidity and mortality rate. From that fact, the study was conducted to describe the current state of knowledge of mothers with children under 5 years old infected with acute respiratory infections in Thai Binh Hospital for Children in 2020. The research results show that the mother’s general knowledge about diseases, care and prevention of ARI is still limited with the average score of knowledge of the intervention group is 22.0 ± 7.0 and the control group is 22, 5 ± 6.5 (maximum of 44 points). Average points of knowledge about disease, care and prevention, respectively: 12.0 ± 4.3; 4.9 ± 2.1; 5.1 ± 1.8 in the intervention group and 12.4 ± 4.2, 5.0 ± 1.8, 5.0 ± 1.9 in the control group. The proportion of mothers with knowledge of both groups was low: 20.0% in the intervention group and 21.7% in the control group. Therefore, it is very necessary to strengthen health education for mothers of health workers, especially nursing staff.

scholarly journals Research of influence of working conditions on the general incidence of foundrymen

2019 ◽  
pp. 156-159
Author(s):  
A. M. Lazarenkov
Keyword(s):  
Working Conditions ◽  
Air Temperature ◽  
Musculoskeletal System ◽  
Respiratory Diseases ◽  
Skin Diseases ◽  
Respiratory Infections ◽  
Acute Respiratory Infections ◽  
High Dust Concentration ◽  
Infections Diseases ◽  
High Dust

Working conditions of workers in foundries and their influence on morbidity with temporary disability are considered. The results of the distribution of diseases in the foundry shops with different character of production for individual nosological forms. It is noted that the increased levels of noise and vibration, high dust concentration in the air of the working area, significant values of air temperature, the intensity of infrared radiation increase the number of cases of morbidity with temporary disability, such as acute respiratory infections, diseases of the musculoskeletal system, respiratory diseases, infections and skin diseases, etc.

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