BIOMEDICAL APPLICATIONS OF MAGNETIC NANOPARTICLES

NANO ◽  
2010 ◽  
Vol 05 (05) ◽  
pp. 245-270 ◽  
Author(s):  
AIGUO WU ◽  
PING OU ◽  
LEYONG ZENG

In this review, the applications of magnetic nanoparticles in biomedicine are summarized and introduced in three parts. (1) A short description of magnetic nanoparticles is explained. (2) Applications of magnetic nanoparticles in biomedicine are summarized. In biology, new progress of the magnetic separation techniques based on magnetic nanoparticles is discussed. In medicine, the magnetic nanoparticles as therapeutic agents (particularly as a hyperthermia agent, a targeted drug delivery carrier, and a magnetofection agent) as well as contrast agents in magnetic resonance imaging (MRI) are explained in detail. (3) A discussion and remarking conclusion of magnetic nanoparticles in biomedical applications are described. Finally, a perspective of the magnetic nanoparticles in biomedicine in future is also described.

RSC Advances ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 6517-6525
Author(s):  
Fatemeh Mohajer ◽  
Ghodsi Mohammadi Ziarani ◽  
Alireza Badiei

Magnetic nanoparticles have been studied for scientific and technological applications such as magnetic storage media, contrast agents for magnetic resonance imaging, biolabelling, separation of biomolecules, and magnetic-targeted drug delivery.


2018 ◽  
pp. 1424-1447
Author(s):  
Irshad Ahmad Wani

Magnetic nanoparticles due to their unique magnetic phenomenon, are gaining immense interest due to the utilization of these properties for a wide variety of applications in various arena especially in biomedical field. This book chapter, therefore, summarizes the synthesis of various types of magnetic nanoparticles using different approaches depending of their ability to generate either single core of multcore magnetic nanoparticles. The various biomedical applications of magnetic nanoparticles like Magnetic Resonance Imaging (MRI), drug delivery etc. along with possible limitations and challenges for their extended applications in medicine are also discussed.


Author(s):  
Irshad Ahmad Wani

Magnetic nanoparticles due to their unique magnetic phenomenon, are gaining immense interest due to the utilization of these properties for a wide variety of applications in various arena especially in biomedical field. This book chapter, therefore, summarizes the synthesis of various types of magnetic nanoparticles using different approaches depending of their ability to generate either single core of multcore magnetic nanoparticles. The various biomedical applications of magnetic nanoparticles like Magnetic Resonance Imaging (MRI), drug delivery etc. along with possible limitations and challenges for their extended applications in medicine are also discussed.


Materials ◽  
2019 ◽  
Vol 12 (24) ◽  
pp. 4096 ◽  
Author(s):  
Connor M. Ellis ◽  
Juan Pellico ◽  
Jason J. Davis

The use of nanoparticulate systems as contrast agents for magnetic resonance imaging (MRI) is well-established and known to facilitate an enhanced image sensitivity within scans of a particular pathological region of interest. Such a capability can enable both a non-invasive diagnosis and the monitoring of disease progression/response to treatment. In this review, magnetic nanoparticles that exhibit a bio-responsive MR relaxivity are discussed, with pH-, enzyme-, biomolecular-, and protein-responsive systems considered. The ability of a contrast agent to respond to a biological stimulus provides not only enriched diagnostic capabilities over corresponding non-responsive analogues, but also an improved longitudinal monitoring of specific physiological conditions.


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