scholarly journals Development of a gold-nanorod-based lateral flow immunoassay for a fast and dual-modal detection of C-reactive protein in clinical plasma samples

RSC Advances ◽  
2021 ◽  
Vol 11 (45) ◽  
pp. 28388-28394
Author(s):  
Renzhu Pang ◽  
Qunyan Zhu ◽  
Jia Wei ◽  
Yaoqi Wang ◽  
Fengqin Xu ◽  
...  

A gold-nanorod-based lateral flow immunoassay for rapid and quantitative detection of CRP by simultaneously monitoring the colorimetric and temperature signals.

2021 ◽  
Vol 188 (9) ◽  
Author(s):  
Vasily G. Panferov ◽  
Nadezhda A. Byzova ◽  
Anatoly V. Zherdev ◽  
Boris B. Dzantiev

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Kyung Mi Park ◽  
Da Jung Chung ◽  
Mijin Choi ◽  
Taejoon Kang ◽  
Jinyoung Jeong

Abstract A fluorescent fullerene nanoparticle (NP)-based lateral flow immunochromatographic assay (LFIA) was developed for the rapid and quantitative detection of C-reactive protein (CRP) in serum. The polyclonal CRP-antibody-conjugated fullerene NPs were simply prepared by 1-ethyl-3-(3-dimethyllaminopropyl)-carbodiimide hydrochloride coupling after carboxylation of fluorescent fullerene NPs. By applying the CRP-antibody-conjugated fullerene NPs to a lateral flow test strip, quantitative analysis of CRP in serum was possible at a concentration range of 0.1–10 ng/ml within 15 min. We anticipate that this novel fluorescent fullerene NP-based LFIA can be useful for the rapid and accurate sensing of biological and chemical species, contributing to the disease diagnosis and prognosis, environmental monitoring, and food safety.


2021 ◽  
Author(s):  
Vasily Panferov ◽  
Nadezhda A. Byzova ◽  
Anatoly V. Zherdev ◽  
Boris B. Dzantiev

We report a new approach to synthesize nanozyme with low consumption of precious Pt-precursor and high peroxidase-mimicking activity. The synthesis includes the formation of gold nanoparticles (Au NPs), the overgrowth of a silver layer over Au NPs (Au@Ag NPs), and the galvanic replacement of Ag with PtCl<sub>6</sub><sup>2-</sup> leading to the formation of Au@Ag–Pt NPs with uniformly deposited catalytic Pt sites. The reported approach facilitates up to 20-times lower consumption of Pt precursor. The use of Au@Ag-Pt NPs as the catalytic label in lateral flow immunoassay results in a 65-fold lower limit of detection (15 pg/mL in serum).


2014 ◽  
Vol 42 (6) ◽  
pp. 635-645 ◽  
Author(s):  
Yongbin Gu ◽  
Yongliang Yang ◽  
Jing Zhang ◽  
ShengXiang Ge ◽  
Zhanghong Tang ◽  
...  

The Analyst ◽  
2018 ◽  
Vol 143 (9) ◽  
pp. 2115-2121 ◽  
Author(s):  
Zhen Rong ◽  
Rui Xiao ◽  
Shuang Xing ◽  
Guolin Xiong ◽  
Zuyin Yu ◽  
...  

We demonstrate a SERS-based lateral flow assay for rapid and quantitative detection of CRP and its potential for in-field evaluation of acute radiation syndrome.


2008 ◽  
Vol 336 (1) ◽  
pp. 30-36 ◽  
Author(s):  
Wingman Leung ◽  
Cangel Puiyee Chan ◽  
Timothy H. Rainer ◽  
Margaret Ip ◽  
George W.H. Cautherley ◽  
...  

2021 ◽  
Vol 329 ◽  
pp. 129241
Author(s):  
Yosita Panraksa ◽  
Amara Apilux ◽  
Sakda Jampasa ◽  
Songchan Puthong ◽  
Charles S. Henry ◽  
...  

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