Malate exchange between the cytosol and mitochondria
Keyword(s):
1. By comparing the relative isotopic yields in glucose and CO2 from precursors of mitochondrial and cytosolic malate, it is evident that the rate of isotopic exchange between these compartments is rapid. 2. A variety of potential inhibitors of malate exchange were tested, but no specific and effective inhibitor of the isotopic exchange has been found. 3. Compounds such as n-butylmalonate and p-iodobenzylmalonate, which have been used as inhibitors of the malate–phosphate transport system in isolated mitochondria, do not appear to be sufficiently specific to be useful in studies with intact cells.
1992 ◽
Vol 174
(9)
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pp. 2754-2762
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1983 ◽
Vol 245
(2)
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pp. F175-F180
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1978 ◽
Vol 83
(4)
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pp. 1360-1364
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1989 ◽
Vol 256
(2)
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pp. G369-G376
Keyword(s):
Keyword(s):
1960 ◽
Vol 199
(4)
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pp. 653-656
1987 ◽
Vol 169
(8)
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pp. 3546-3555
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