miR-1343 attenuates pathways of fibrosis by targeting the TGF-β receptors
Keyword(s):
A previously uncharacterized miRNA, miR-1343, was found to target and reduce the expression of transforming growth factor β (TGF-β) receptors 1 and 2. This led to significantly repressed TGF-β signalling in lung epithelial cells and fibroblasts and corresponding reductions in experimental markers of fibrosis.
2012 ◽
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