A model for Rab GTPase localization
2005 ◽
Vol 33
(4)
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pp. 627-630
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Keyword(s):
The human genome encodes almost 70 Rab GTPases. These proteins are C-terminally geranylgeranylated and are localized to the surfaces of distinct membrane-bound compartments in eukaryotic cells. This mini review presents a working model for how Rabs achieve and maintain their steady-state localizations. Data from a number of laboratories suggest that Rabs participate in the generation of macromolecular assemblies that generate functional microdomains within a given membrane compartment. Our data suggest that these complex interactions are important for the cellular localization of Rab proteins at steady state.
2018 ◽
Vol 46
(6)
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pp. 1707-1712
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Keyword(s):
2012 ◽
Vol 40
(6)
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pp. 1373-1377
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2018 ◽
Vol 46
(3)
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pp. 683-690
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2005 ◽
Vol 33
(4)
◽
pp. 652-656
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2017 ◽
Vol 28
(6)
◽
pp. 712-715
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2006 ◽
Vol 173
(6)
◽
pp. 917-926
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2019 ◽
Vol 218
(12)
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pp. 4157-4170
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Keyword(s):