Effect of Age on Oxygen-Binding in Normal Human Subjects
Keyword(s):
1. Oxygen-binding, plasma and intra-erythrocytic pH, and haemoglobin, 2,3-diphosphoglycerate and inorganic phosphate concentrations were measured in sixty-two healthy non-smokers aged between 18 and 89 years. 2. P50 (oxygen tension at 50% oxygen saturation) expressed at plasma pH 7·40 and Pco2 5·33 kPa showed a positive correlation with age. 3. This correlation of P50 with age was closer when P50 was expressed at a constant intra-erythrocytic pH 7·20. On average P50 at intra-erythrocytic pH 7·20 increased from 3·59 kPa at 20 years to 3·96 kPa at 90 years of age. 4. 2,3-Diphosphoglycerate, inorganic phosphate, haemoglobin and mean corpuscular haemoglobin concentrations did not correlate with P50 or with age.
1938 ◽
Vol 124
(1)
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pp. 13-21
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1944 ◽
Vol 142
(5)
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pp. 700-707
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Observations on a Relationship between Steroid Metabolism and the Concentration of Plasma Fibrinogen
1963 ◽
Vol 10
(02)
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pp. 400-405
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Keyword(s):
1979 ◽
Vol 42
(02)
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pp. 694-704
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Keyword(s):
1996 ◽
Vol 351
(1346)
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pp. 1455-1462
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2010 ◽
Vol 74
(3)
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pp. 510-519
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Keyword(s):
2007 ◽
Vol 61
(11)
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pp. 1812-1818
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