The Effects of Metoprolol on Ambulatory Blood Pressure

1979 ◽  
Vol 57 (s5) ◽  
pp. 375s-377s ◽  
Author(s):  
S. Mann ◽  
M. W. Millar Craig ◽  
D. G. Altman ◽  
D. I. Melville ◽  
E. B. Raftery
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Arterial Pressure ◽  
Ambulatory Blood Pressure ◽  
Continuous Monitoring ◽  
Hypertensive Patients ◽  
Pressure Changes ◽  
Circadian Patterns

1. Continuous monitoring of arterial pressure was performed via an indwelling cannula over 24 h in 12 hypertensive patients before treatment and again 2–4 months after starting metoprolol (100 mg twice daily). 2. During treatment, heart rate and systolic and diastolic pressures were significantly reduced. 3. The circadian patterns of heart rate and blood pressure changes were similar before and during therapy.

The Influence of Physical Activity on Arterial Pressure during Ambulatory Recordings in Man

1980 ◽  
Vol 58 (1) ◽  
pp. 115-117 ◽  
Author(s):  
D. B. Rowlands ◽  
T. J. Stallard ◽  
R. D. S. Watson ◽  
W. A. Littler
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
Heart Rate ◽  
Arterial Pressure ◽  
Ambulatory Blood Pressure ◽  
Physical Activities ◽  
Hypertensive Patients ◽  
Arterial Blood ◽  
Significant Difference ◽  
Hypotensive Therapy

1. Ambulatory blood pressure recordings were made over a 48 h period on six hypertensive patients. The conditions of study were standardized, particularly with regard to physical activity, and during one period of each day the patients were randomly allocated to be active or inactive. 2. Results show that blood pressure was highest during physical activity and lowest during sleep. There was no significant difference between the arterial pressures measured during the same physical activities carried out at the same time each day. However, during the same time on consecutive days when activity was randomized, there was a significant difference between the pressure recordings during physical activity compared with those during inactivity. Heart rate changes showed a similar trend during the randomized period. 3. Physical activity and sleep have a profound effect on continuous arterial blood pressure recordings and these are independent of time alone. These observations should be taken into account when using this ambulatory system to assess hypotensive therapy.

scholarly journals Ambulatory blood pressure monitoring changes in hypertensive patients

2019 ◽  
Vol 2 (8) ◽  
pp. 53-57
Author(s):  
V.S. Pasko
Keyword(s):  
Blood Pressure ◽  
Arterial Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Ambulatory Blood Pressure Monitoring ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Pressure Monitoring ◽  
Middle Aged ◽  
Hypertensive Patients

The aim of the study was to determine the peculiarities of ABPM indices in middle-aged and elderly hypertensive patients depending on the daily BP profile. Material and methods. Indices of ambulatory blood pressure monitoring were identified in 57 middle-aged patients (45-59 years) (group I) and 43 elderly patients (60-74 years) (group II), who underwent two-week in-patient treatment. The control group consisted of 15 patients for every of the surveyed categories (group III - middle-aged and group IV – elderly respectively) matched with basic by age and gender. Results. We have shown that one of the factors that determines the change in hemodynamics in patients with essential hypertension is age, with the age patients experience the decrease in diastolic blood pressure with steadily increased systolic blood pressure, that should be considered in the prescription of antihypertensive treatment. With age, a gradual increase in systolic blood pressure is associated with the increased aortic stiffness, partially with the increase in collagen and the decrease in elastic fibrils and the formation of isolated systolic hypertension. Thus, it is proved that in the formation of isolated hypertension the growth of pulse blood pressure for more than 60 mm Hg is unfavorable in a development of cerebrovascular events. Pulse arterial blood pressure was stronger risk factor than systolic blood pressure and diastolic blood pressure or average arterial pressure in the elderly. Recently, taking into account age characteristics, all three indices were recognized as comparable predictors at the age of 50-59 years as the transitional period, and at the age of 60-79 years diastolic blood pressure adversely affecting the cardiovascular risk, increased pulse blood pressure prognostically above the level of systolic arterial pressure.

Electrocardiographic and arterial pressure changes in female dogs subjected to epidural anesthesia with different doses of morphine

2017 ◽  
Vol XXII (130) ◽  
pp. 60-70
Author(s):  
Mariana Werneck Fonseca ◽  
Verônica Batista de Albuquerque ◽  
Gabriel T. N. Martins Ferreira ◽  
Marcelo Augusto de Araújo ◽  
Wagner Luis Ferreira ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Arterial Pressure ◽  
Systolic Blood Pressure ◽  
Blood Lactate ◽  
Rectal Temperature ◽  
Epidural Anesthesia ◽  
Epidural Morphine ◽  
Pressure Changes ◽  
Different Doses

This article investigates the electrocardiographic and blood pressure changes caused by different doses of morphine administered epidurally to bitches undergoing elective ovariohysterectomy. Twenty-four healthy bitches weighing 9.8 ± 4.1 kg were assigned to three experimental groups (in each group, n = 8): (i) group M0.1: 0.1 mg/kg morphine; (ii) group M0.15: 0.15 mg/kg morphine; and (iii) group M0.2: 0.2 mg/kg morphine. In all groups, levobupivacaine was added to achieve a total volume of 0.33 mL/kg. During the procedures, the following parameters were controlled: heart rate and rhythm, systolic blood pressure, rectal temperature and blood lactate. The data were analyzed by means of statistical methods of analysis of variance, such as Kruskal-Wallis, Fisher and Tukey tests. Epidural morphine did not cause significant electrocardiographic or blood pressure changes in the tested doses, which makes the use of this drug a viable alternative for epidural anesthesia.

The Autonomic Nervous Tone Abnormalities in the Genesis of the Impaired Baroreflex Responsiveness in Borderline Hypertensive Subjects

1982 ◽  
Vol 62 (6) ◽  
pp. 581-588 ◽  
Author(s):  
Massimo Volpe ◽  
Bruno Trimarcoy ◽  
Bruno Ricciardelli ◽  
Carlo Vigorito ◽  
Nicola De Luca ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Arterial Pressure ◽  
Normal Subjects ◽  
Tissue Pressure ◽  
Combined Administration ◽  
Propranolol Treatment ◽  
The Mean ◽  
Pressure Changes ◽  
Neck Chamber

1. The effects of intravenous administration of neostigmine and propranolol, individually or in combination, on baroreflex responsiveness have been evaluated in 18 borderline hypertensive subjects and in 14 age-matched control subjects. 2. Baroreceptor sensitivity was tested by evaluating both heart rate response to phenylephrine-induced increase in arterial pressure, and heart rate and blood pressure changes induced by increasing neck-tissue pressure by means of a neck-chamber. 3. In borderline hypertensive subjects a reduced baroreflex responsiveness was demonstrated with both stimuli as compared with normal subjects. Neostigmine administration improved consistently both reflex responses. Similarly, after propranolol treatment, borderline hypertensive subjects showed a significant enhancement of the baroreflex sensitivity. Finally, the combined administration of neostigmine and propranolol restored the baroreflex responses. In fact, both the mean slopes of the regression lines between blood pressure and R-R interval after phenylephrine and the increase in mean arterial pressure and heart rate induced by the reduction in carotid transmural pressure in borderline hypertensive subjects were similar to those observed in normals. 4. These findings indicate that in borderline hypertensive subjects the impairment of baroreflex responsiveness is mainly due to abnormalities of autonomic regulation.

Effects of cigarette smoking on ambulatory blood pressure, heart rate, and heart rate variability in treated hypertensive patients

2016 ◽  
Vol 38 (6) ◽  
pp. 510-513 ◽  
Author(s):  
Yuko Ohta ◽  
Yuhei Kawano ◽  
Shinichiro Hayashi ◽  
Yoshio Iwashima ◽  
Fumiki Yoshihara ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Heart Rate Variability ◽  
Cigarette Smoking ◽  
Ambulatory Blood Pressure ◽  
Hypertensive Patients

scholarly journals Circadian Blood Pressure Variability in Hypertensive Patients with Coronary Heart Disease.

2020 ◽  
Vol 3 (2) ◽  
pp. 01-10
Author(s):  
Jorge Luis León Alvarez ◽  
Michel Curbelo López ◽  
Tania Hidalgo Costa ◽  
Miguel Ángel Yanes Quesada ◽  
Raúl Orlando Calderín Bouza ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Ambulatory Blood Pressure Monitoring ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Pressure Monitoring ◽  
Hypertensive Patients ◽  
And Control ◽  
Circadian Patterns

Introduction and objectives: Coronary heart disease is one of the complications of hypertension. Ambulatory blood pressure monitoring allows studying the different circadian patterns of blood pressure, but there is not enough evidence linking coronary heart disease with different circadian patterns. This research was carried out with the purpose of characterizing the circadian patterns of blood pressure in patients with essential hypertension and coronary heart disease. Methods: Descriptive and transversal research in 68 hypertensive patients with coronary heart disease who underwent ambulatory blood pressure monitoring. The different circadian patterns of blood pressure were related to the different forms of coronary heart disease and to the control of blood pressure. Results: In the sample, women (60.3%) predominated over men (39.7%). The ages were between 45 to 59 (63.3%) and those 60 and over (36.7%). 44.1% did not have their blood pressure under control, 45.6% were overweight and 38.2% were obese. The abnormal patterns were dipper 42.6%, non-dipper 41.2%, extreme dipper 7.4% and riser 8.8%. Morning surge was observed in 29 patients (42.6%), statistically significant in relation to the control of blood pressure (p = 0.033), but not with the different types of coronary heart disease studied. Conclusions: A statistically significant relationship was found between morning surge and control of blood pressure.

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