scholarly journals Selected features of morpho-functional reactions of eukaryotic microorganisms grown in the presence of maghemite iron oxide nanoparticles obtained by laser target evaporation

2018 ◽  
Vol 185 ◽  
pp. 10004 ◽  
Author(s):  
Elena V. Simonova ◽  
Tatyana P. Denisova ◽  
Roman T. Khandukhanov ◽  
Grigory Yu. Melnikov ◽  
Anatoly I. Medvedev ◽  
...  
Keyword(s):  
Biological Activity ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Solid Medium ◽  
Oxide Nanoparticles ◽  
Significant Excess ◽  
Laser Target ◽  
Eukaryotic Microorganisms ◽  
Fe Ions ◽  
Number Of Cells

Biological activity of iron introduced into nutrient medium as a suspension of iron oxide nanoparticles (MNPs) synthesized by the laser target evaporation was investigated. Exophiala nigrum (E. nigrum) eukaryotes were grown either in the presence or in absence of MNPs. De-aggregated suspensions of Fe2.75O4 MNPs were added in concentrations of 1 to 104 maximum permissive dose (MPD, being 0.3 mg/L of Fe ions in water). Cells were exposed for 24 to 96 hours periods and then plated onto a solid medium. The effect of MNPs was evaluated by the change in the number of cells during exposure and the number and morphology of the colonies. For 1-10 MPD yeast showed unaltered characteristics. For 100 or 1000 MPD for 72 hours of exposure and above the number of cells increases up to 30 times in comparison with the control. A pronounced stimulating effect was revealed at 104 MPD of iron. A significant excess of the number of cells was observed for the first day. At exposures of 72 and 96 hours the differences in the number of cells in comparison with the control were 11 and 30 times, respectively. A change in the colonies morphology was observed at 100 MPD concentration.

EB PVD synthesis of iron oxide nanoparticles and their biological activity

2020 ◽  
Vol 2020 (3) ◽  
pp. 54-61
Author(s):  
S.E. Litvin ◽  
◽  
Yu.A. Kurapov ◽  
E.M. Vazhnichaya ◽  
Ya.A. Stel’makh ◽  
...  
Keyword(s):  
Biological Activity ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

Enhancing bio-gas production from kitchen waste using BSA-iron oxide nanoparticles in miniature level bio-reactor

2016 ◽  
Vol 78 (2) ◽  
pp. 71-77
Author(s):  
R.S.S. Prabhahar ◽  
N. Vignesh
Keyword(s):  
Iron Oxide ◽  
Iron Oxides ◽  
Iron Oxide Nanoparticles ◽  
Metal Ion ◽  
Biogas Production ◽  
Gas Production ◽  
Oxide Nanoparticles ◽  
Anaerobic Conditions ◽  
The Media ◽  
Fe Ions

Purpose: This study focuses on increasing production of biogas as an alternative energyfrom biodegradable wastes (BWs) using BSA coated iron oxides nanoparticles, in view ofsolving waste management at household level. Many attempts have been performed in orderto increase biogas production, including thermal pre-treatment of organic waste, but all ofthem present limited industrial applications. Iron has been shown to enhance anaerobicdigestion, but there are severe drawbacks for introducing the metal ion in an anaerobicclosed reactor.Design/methodology/approach: Process for the production of biogas from biodegradablematerial which comprises the steps of: (a) adding the biodegradable material to the Bioreactor,(b) inoculating the microorganisms in the digester,(c) synthesis iron oxides and BSApowder coated on the particles (d) adding a colloidal solution of surface-modified BSA-ironoxide nanoparticles to the reactor; (e) providing anaerobic conditions; (f) carrying out theanaerobic digestion; and (g) collecting the biogas, wherein the steps (a), (b) and (c) can becarried out in any order. It also comprises the use of BSA-iron oxide nanoparticles capableof supplying Fe ions to the media for biogas production in anaerobic conditions and in thepresence of Fe ions in the media.

Biocompatible Ferrofluids With Iron Oxide Nanoparticles Fabricated by Laser Target Evaporation

2015 ◽  
Vol 6 ◽  
pp. 1-4 ◽  
Author(s):  
Iuliia P. Novoselova ◽  
Alexander P. Safronov ◽  
Oleg M. Samatov ◽  
Anatoly I. Medvedev ◽  
Galina V. Kurlyandskaya
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Laser Target

Effects of 2,3-dimercaptosuccinic acid modified Fe2O3 nanoparticles on microstructure and biological activity of cardiomyocytes

RSC Advances ◽  
2015 ◽  
Vol 5 (25) ◽  
pp. 19493-19501 ◽  
Author(s):  
Yongchao Mou ◽  
Jin Zhou ◽  
Fei Xiong ◽  
Hong Li ◽  
Hongyu Sun ◽  
...  
Keyword(s):  
Biological Activity ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Dimercaptosuccinic Acid ◽  
Oxide Nanoparticles ◽  
Fe2o3 Nanoparticles ◽  
Intracellular Ros

Iron oxide nanoparticles did not interfere with the microstructure, but decreased the intracellular ROS content of cardiomyocytes.

scholarly journals Physical synthesis of iron oxide nanoparticles and their biological activity in vivo

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Yurii A. Kurapov ◽  
Elena M. Vazhnichaya ◽  
Stanislav E. Litvin ◽  
Sergey M. Romanenko ◽  
Gennadii G. Didikin ◽  
...  
Keyword(s):  
Biological Activity ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Physical Synthesis

TARGETING CYCLIN B1 WITH ANTISENSE OLIGONUCLETOTIDES- COATED SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES

2018 ◽  
Vol 6 (10) ◽  
Author(s):  
Hosam Zaghloul ◽  
Doaa A. Shahin ◽  
Ibrahim El- Dosoky ◽  
Mahmoud E. El-awady ◽  
Fardous F. El-Senduny ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Cellular Uptake ◽  
Superparamagnetic Iron Oxide ◽  
Cyclin B1 ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Mcf7 Cells ◽  
M Phase ◽  
The Impact

Antisense oligonucleotides (ASO) represent an attractive trend as specific targeting molecules but sustain poor cellular uptake meanwhile superparamagnetic iron oxide nanoparticles (SPIONs) offer stability of ASO and improved cellular uptake. In the present work we aimed to functionalize SPIONs with ASO targeting the mRNA of Cyclin B1 which represents a potential cancer target and to explore its anticancer activity. For that purpose, four different SPIONs-ASO conjugates, S-M (1–4), were designated depending on the sequence of ASO and constructed by crosslinking carboxylated SPIONs to amino labeled ASO. The impact of S-M (1–4) on the level of Cyclin B1, cell cycle, ROS and viability of the cells were assessed by flowcytometry. The results showed that S-M3 and S-M4 reduced the level of Cyclin B1 by 35 and 36%, respectively. As a consequence to downregulation of Cyclin B1, MCF7 cells were shown to be arrested at G2/M phase (60.7%). S-M (1–4) led to the induction of ROS formation in comparison to the untreated control cells. Furthermore, S-M (1–4) resulted in an increase in dead cells compared to the untreated cells and SPIONs-treated cells. In conclusion, targeting Cyclin B1 with ASO-coated SPIONs may represent a specific biocompatible anticancer strategy.

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