scholarly journals Recent developments in mitochondrial medicine (Part 1)

4open ◽  
2021 ◽  
Vol 4 ◽  
pp. 2
Author(s):  
Volkmar Weissig ◽  
Marvin Edeas
Keyword(s):  
Mitochondrial Dna ◽  
19Th Century ◽  
Structure And Function ◽  
Mitochondrial Medicine ◽  
Dna Mutations ◽  
Recent Developments ◽  
Number Of Publications ◽  
And Function ◽  
The 19Th Century ◽  
Made In

Research into elucidating structure and function of mitochondria has been quite steady between the time of discovery during the end of the 19th century until towards the late 1980’s. During the 1990s there was talk about a “comeback” of this organelle reflecting a widely revitalized interest into mitochondrial research which was based on two major discoveries made during that time. The first was the etiological association between human diseases and mitochondrial DNA mutations, while the second revealed the crucial function of mitochondria during apoptosis. The March 5th, 1999 issue of Science even featured a textbook image of a mitochondrion on its front cover and was entirely dedicated to this organelle. Whilst the term “comeback” might have been appropriate to describe the general excitement surrounding the new mitochondrial discoveries made during the 1990s, a term for describing the progress made in mitochondrial research during the last two decades is difficult to find. Between 2000 and 2020 the number of publications on mitochondria has skyrocketed. It is now widely accepted that there hardly exists any human disease for which either the etiology or pathogenesis does not seem to be associated with mitochondrial malfunction. In this review we will discuss and follow several lines of mitochondrial research from their early beginnings up to the present. We hope to be able to convince the reader of what we expressed about a decade ago, that the future of medicine will come through mitochondria.

scholarly journals Das Testament als eine Textsorte. Eine linguistische Analyse des Testaments des galizischen Adligen Herman de Brunicki aus dem Jahre 1835

2019 ◽  
pp. 35-51
Author(s):  
Waldemar Czachur ◽  
Agnieszka Zimmer
Keyword(s):  
19Th Century ◽  
Structure And Function ◽  
Legal Language ◽  
The Will ◽  
And Function ◽  
The 19Th Century

The aim of the article is to show the specific characteristics of the Galician legal language in the first half of the 19th century. The article analyses the 1835 will of Baron Herman de Brunicki. First, the pattern of the will, its structure and function are examined. Further on, the author focuses on the graphematic, lexical and syntactic levels of the will.

scholarly journals History of studying the kidney pathology in the mirror of numismatics. Report 3. Development of urology

2021 ◽  
pp. 82-88
Author(s):  
O.V. Syniachenko ◽  
M. O. Kolesnyk ◽  
N.M. Stepanova ◽  
M.V. Iermolaieva
Keyword(s):  
19Th Century ◽  
Scientific Discipline ◽  
Structure And Function ◽  
Historical Science ◽  
Historical Events ◽  
Stages Of Development ◽  
Modern Times ◽  
History Of ◽  
And Function ◽  
The 19Th Century

The branch of historical science of numismatics (from the Latin "numisma" - coin) originated in the 19th century and became closely connected with economics, politics, culture and law, it includes a thematic study of coins, medals and plaque. Best of all, the history of uronephrology is illustrated by various forms of the medalist educational art (exonum or paranumismatics), and the medal became the prototype of the memorial coin. This work presents a catalog of more than 400 numismatic materials (including some unique, first cited), reflects the stages of development of the study of the structure and function of the kidneys, methods for diagnosing and treating diseases, there are links to significant historical events, brief biographies of physicians who have made an invaluable contribution are mentioned into the formation of this scientific discipline. The development of urology over 520 years of historical epochs of the New and Modern times were presented, portraits on 60 numismatic materials of well-known specialists-urologists and kidney transplantologists were presented, scientific forums of urologists were reflected on commemorative medals.

Structure and Function in Neurology and Psychiatry

1990 ◽  
Vol 157 (4) ◽  
pp. 481-490 ◽  
Author(s):  
E. H. Reynolds
Keyword(s):  
Nervous System ◽  
19Th Century ◽  
Social Factors ◽  
Structure And Function ◽  
Complex Dynamic ◽  
Neurological Patients ◽  
Structural Disease ◽  
And Function ◽  
The 19Th Century

In the 19th century the triumphs of neuropathology and the clinico-anatomical method led to the evolution of neurology as a separate ‘organically’ based discipline associated with the concept of functional localisation. At the same time the growth of psychodynamic psychiatry contributed to the progressive separation of the two disciplines, with neuropsychiatry sitting uneasily in the middle. Psychiatrists are now showing increasing interest in the structure and function of the nervous system, but are having difficulty in integrating their findings into ‘functional’ diseases. This may be because disorder of function in the nervous system is much more complex than previously envisaged. The function of the nervous system is profoundly affected by psychological and social factors. The view that neurology is wholly ‘organic’ and synonymous with structural disease of the nervous system is fallacious. Neurological patients have complex dynamic disorders of function in the nervous system whether or not structural disease is present.

scholarly journals History of studying the kidney pathology in the mirror of numismatics. Report 2. Development of nephrology

2020 ◽  
pp. 67-75
Author(s):  
O.V. Syniachenko ◽  
M.O. Kolesnyk ◽  
N.M. Stepanova ◽  
M.V. Iermolaieva
Keyword(s):  
Urinary Tract ◽  
19Th Century ◽  
Middle Ages ◽  
Scientific Discipline ◽  
Structure And Function ◽  
Historical Science ◽  
Historical Events ◽  
History Of ◽  
And Function ◽  
The 19Th Century

The branch of historical science of numismatics (from the Latin "numisma" - coin) originated in the 19th century and became closely connected with economics, politics, culture and law, it includes a thematic study of coins, medals and plaque. Best of all, the history of uronephrology is illustrated by various forms of medalist educational art (exonum or paranumismatics), and the medal became the prototype of the memorial coin. This work presents a catalog of more than 400 numismatic materials (including some unique, first cited), reflects the stages of development of the study of the structure and function of the kidneys, methods for diagnosing and treating diseases, there are links to significant historical events, brief biographies of physicians who have made an invaluable contribution are mentioned into the formation of this scientific discipline. The work presents a role in the origin of the study of kidney and urinary tract diseases of ancient physicians (Aretea, Aristotle, Galen, Hippocrates, Rufus, Sushruta, Empedocles) and doctors of the Middle Ages (Avicenna, Da Carpi, Panaskerteli, Paracelsus, Sun Simiao).

scholarly journals History of studying the kidney pathology in the mirror of numismatics. Report 1. Antiquity and middle ages

2020 ◽  
pp. 74-80
Author(s):  
O.V. Syniachenko ◽  
M.O. Kolesnyk ◽  
N.M. Stepanova ◽  
M.V. Iermolaieva
Keyword(s):  
Urinary Tract ◽  
19Th Century ◽  
Middle Ages ◽  
Scientific Discipline ◽  
Structure And Function ◽  
Historical Science ◽  
Historical Events ◽  
History Of ◽  
And Function ◽  
The 19Th Century

The branch of historical science of numismatics (from the Latin "numisma" - coin) originated in the 19th century and became closely connected with economics, politics, culture and law, it includes a thematic study of coins, medals and plaque. Best of all, the history of uronephrology is illustrated by various forms of medalist educational art (exonum or paranumismatics), and the medal became the prototype of the memorial coin. This work presents a catalog of more than 400 numismatic materials (including some unique, first cited), reflects the stages of development of the study of the structure and function of the kidneys, methods for diagnosing and treating diseases, there are links to significant historical events, brief biographies of physicians who have made an invaluable contribution are mentioned into the formation of this scientific discipline. The work presents a role in the origin of the study of kidney and urinary tract diseases of ancient physicians (Aretea, Aristotle, Galen, Hippocrates, Rufus, Sushruta, Empedocles) and doctors of the Middle Ages (Avicenna, Da Carpi, Panaskerteli, Paracelsus, Sun Simiao).

Kontrast und Wissen

2009 ◽  
Vol 54 (1) ◽  
pp. 69-102
Author(s):  
Robin Rehm
Keyword(s):  
19Th Century ◽  
Edmund Husserl ◽  
Specific Knowledge ◽  
Max Scheler ◽  
Black And White ◽  
Black Circle ◽  
Black Cross ◽  
Definition Of ◽  
And Function ◽  
The 19Th Century

Kasimir Malewitschs suprematistische Hauptwerke ›Schwarzes Quadrat‹, ›Schwarzer Kreis‹ und ›Schwarzes Kreuz‹ von 1915 setzen sich aus schwarzen Formen auf weißem Grund zusammen. Der Typus des Schwarzweißbildes weist überraschende Parallelen zu den bildlichen Wahrnehmungsinstrumenten auf, die vom ausgehenden 18. bis Anfang des 20. Jahrhunderts in den Experimenten der Farbenlehre, physiologischen Optik und Psychologie verwendet worden sind. Die vorliegende Studie untersucht diese Parallelen in drei Schritten: Zunächst erfolgt eine allgemeine Charakterisierung des Schwarzweißbildes mit Hilfe des Kontrastbegriffs von Edmund Husserl. Des weiteren wird die Entstehung und Funktion des schwarzweißen Kontrastbildes in den Wissenschaften des 19. Jahrhunderts typologisch herausgearbeitet. Unter Berücksichtigung des Wissensbegriffs von Max Scheler wird abschließend die Spezifik des Wissens eruiert, das die Schwarzweißbilder sowohl in der Malerei Malewitschs als auch in den genannten Wissenschaften generieren. Malevich’s main Suprematist works, such as ›Black Square‹, ›Black Circle‹, and ›Black Cross‹ from 1915, consist of black shapes on white ground. Surprisingly this series of shapes strongly resembles scientific black-and-white images used for research on colour theory, physiological optics, and psychology throughout the 19th century. This paper examines the parallels between Malevich’s paintings and the scientific drawings in three steps: It first characterizes black-and-white images in general, using Edmund Husserl’s definition of the term ›contrast‹. Secondly, the paper investigates the development and function of black-and-white images as tools of perception in the sciences. It finally discusses the specific knowledge generated through Malevich’s art and through scientific black-and-white images, following Max Scheler’s phenomenological identification of knowledge.

scholarly journals History of otorhinolaryngology in Germany before 1921

HNO ◽  
2021 ◽  
Vol 69 (5) ◽  
pp. 338-365
Author(s):  
Albert Mudry ◽  
Robert Mlynski ◽  
Burkhard Kramp
Keyword(s):  
Head And Neck ◽  
19Th Century ◽  
Neck Surgery ◽  
German Society ◽  
100Th Anniversary ◽  
Head And Neck Surgery ◽  
History Of ◽  
Academic Organization ◽  
The 19Th Century ◽  
Made In

AbstractIn 2021, the German Society of Otorhinolaryngology, Head and Neck Surgery is celebrating the 100th anniversary of its foundation. The aim of this article is to present the main inventions and progress made in Germany before 1921, the date the society was founded. Three chronological periods are discernible: the history of otorhinolaryngology (ORL) in Germany until the beginning of the 19th century, focusing mainly on the development of scattered knowledge; the birth of the sub-specialties otology, laryngology (pharyngo-laryngology and endoscopy), and rhinology in the 19th century, combining advances in knowledge and implementation of academic structures; and the creation of the ORL specialty at the turn of the 20th century, mainly concentrating on academic organization and expansion. This period was crucial and allowed for the foundation of the German Society of Otorhinolaryngology, Head and Neck Surgery on solid ground. Germany played an important role in the development and progress of ORL internationally in the 19th century with such great contributors as Anton von Tröltsch, Hermann Schwartze, Otto Körner, Rudolf Voltolini, and Gustav Killian to mention a few.

scholarly journals PEREDARAN OPIUM DI MINANGKABAU ABAD KE-19

2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Muhammad Nasir
Keyword(s):  
19Th Century ◽  
Large Scale ◽  
Reform Movement ◽  
Religious Groups ◽  
Opium Trade ◽  
Islamic Reform ◽  
History Of ◽  
The 19Th Century ◽  
Made In

This article discusses the history of Minangkabau in the 19th century AD. One of the themes of 19th century Minangkabau history is the Islamic reform movement promoted by religious groups commonly called the Padri movement. One of the central issues of the Padri movement was eradicating the habit of drinking alcoholism that occurred in Minangkabau society. The habit of smoking the drug that comes from boiling opium certainly indicates the existence of the drug on a large scale. Therefore, this article will present a picture of the opium trade in Minangkabau in the 19th century from upstream (providers) to downstream (dealers). It is hoped that this article will be useful as an explanation for the habit of smoking made in the Minangkabau community at that time.

scholarly journals Manowce polskiej egiptologii XIX wieku. Jerzego Ręczyńskiego „przekład” tekstu kamienia z Rosetty

2018 ◽  
Vol 10 ◽  
pp. 297-311
Author(s):  
Hieronim Kaczmarek
Keyword(s):  
19Th Century ◽  
Contemporary Research ◽  
Ancient Egyptian ◽  
Rosetta Stone ◽  
History Of ◽  
Number Of Publications ◽  
Research Standards ◽  
The 19Th Century

The paper is one of a number of publications devoted to perception of the history of ancient Egyptian civilization in Poland by the end of the 19th century. It presents Jerzy Ręczyński’s (1905-1899) ‘attempts’ to study Egyptian inscriptions (the Rosetta Stone), results of which have to be absolutely rejected according to contemporary research standards.

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