scholarly journals Ameloblastoma of the mandible: analysis of radiographic and histopathological features

2020 ◽  
Vol 27 (1) ◽  
pp. 6
Author(s):  
Sanjay Ranchod ◽  
Fadi Titinchi ◽  
Nashreen Behardien ◽  
Jean Morkel
Keyword(s):  
Root Resorption ◽  
Anatomical Variation ◽  
Female Ratio ◽  
Black African ◽  
Histopathological Features ◽  
Patient Demographics ◽  
Odontogenic Origin ◽  
African Patients ◽  
Male To Female ◽  
Common Benign Tumour

Introduction: Ameloblastoma is the most common benign tumour of odontogenic origin in Africa and presents five times more in the mandible than the maxilla. The presentation of ameloblastoma in the mandible is unique due to its anatomical variation and hence the aim of this study was to analyse the radiographic and histopathological features of ameloblastoma involving the mandible. Materials and methods: This was a retrospective, descriptive study of all histopathologically diagnosed ameloblastoma of the mandible over a period of 45 years. Patient demographics, radiographic and histopathological features were recorded and compared to previous studies. Results: A total of 148 lesions were included. The male to female ratio was nearly equal (1.05:1). The majority of patients were below 50 years of age (83.77%) and were black African (58.8%). The posterior region was the most affected site with majority of lesions presenting with multilocular appearance (68.24%) and root resorption (66.38%). Histologically, conventional ameloblastoma was the most common variant (48.65%). Conclusions: Mandibular ameloblastoma had a higher predilection for black African patients with higher prevalence of mixed density lesions when compared to previous studies. The size of lesions in this sample was considerably larger than those reported in previous studies. In addition, lesions in this sample also exhibited marked cortical expansion as well as root resorption.

scholarly journals EP.WE.561The impact of COVID-19 on infra-inguinal revascularisation in patients with symptomatic peripheral occlusive arterial disease

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Sophie Tait ◽  
Kay McGillivray ◽  
Roisin McKenna ◽  
Keith Hussey
Keyword(s):  
Arterial Disease ◽  
Specific Reference ◽  
Peripheral Occlusive Arterial Disease ◽  
Female Ratio ◽  
Patient Demographics ◽  
Occlusive Arterial Disease ◽  
Male To Female ◽  
Clear Change ◽  
Extremity Amputation ◽  
Index Cases

Abstract Introduction Standard Operating Procedures were revised in response to the Covid-19 pandemic. There are descriptions from across Europe of increased rates of major extremity amputation. We have explored practice in a regional vascular unit serving two Health Boards in Scotland with specific reference to infra-inguinal revascularisation for patients with symptomatic peripheral occlusive arterial disease. Methods A retrospective review of the administrative theatre database was performed. Pre-Covid (1st April–July 31st 2019) and peri-Covid (1st April-31st July 2020) periods were examined and index cases identified. Practice and outcomes were examined. Results There was a 50% reduction in scheduled theatre sessions during the peri-Covid period. There were 100 procedures performed pre-Covid and 71 procedures performed during the peri-Covid period. The patient demographics were comparable – mean age 68-years with a male to female ratio of 1.6:1. Intervention for chronic limb threatening ischaemia was much more common in the peri-Covid period than in the pre-Covid period (94% versus 64% respectively). There was a clear change in anaesthetic practice with regional anaesthesia more commonly performed in the peri-Covid period (49% versus 12% respectively). There was no difference in the types of revascularisation performed. The 30-day mortality in the peri-Covid period was less than in the pre-Covid period (3% vs 1.4%). Conclusion The Covid-19 pandemic created imperatives that necessitated re-structure of service. Despite a reduction in theatre access we have managed to maintain a limb salvage service for patients with chronic limb threatening ischaemia.

scholarly journals Pilomatrixcarcinoma of the Foot: A New Localization of an Extremely Rare Adnexal Tumour

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 793
Author(s):  
Gerardo Cazzato ◽  
Anna Colagrande ◽  
Paolo Romita ◽  
Caterina Foti ◽  
Leonardo Resta ◽  
...  
Keyword(s):  
Current Literature ◽  
De Novo ◽  
Distal Phalanx ◽  
Follicular Neoplasm ◽  
Female Ratio ◽  
Histopathological Features ◽  
First Case ◽  
The Face ◽  
Male To Female ◽  
Adnexal Tumour

Pilomatrixcarcinoma is a very rare follicular neoplasm that shows matrical differentiation. The majority of these lesions originate de novo, while only a few cases of transformation of pilomatricoma (calcifying epithelioma of Malherbe) have been described in the literature. The neoplasm affects mostly middle-aged males with a male-to-female ratio of 3–4:1. The most common localizations are the face, head, trunk and extremites, though there are a few reports of pilomatrixcarcinoma of the eyelid, eyebrow, axilla and clitorid. Here, we describe the first case of a pilomatrixcarcinoma on the anterolateral surface of the first toe of the left foot of an 83-year-old patient, which developed in less than six months and led to amputation of the distal phalanx. We report a brief review of the current literature with particular emphasis on histopathological features useful for diagnosis.

scholarly journals A retrospective study on clinicopathological correlation of cutaneous tuberculosis

2018 ◽  
Vol 4 (4) ◽  
pp. 595 ◽  
Author(s):  
Rajkumar Kannan ◽  
Lakshmanan Chellappan ◽  
Sridhar Venu ◽  
Muthusubramanian Chandrasekar
Keyword(s):  
Skin Biopsy ◽  
Lupus Vulgaris ◽  
Active Lesion ◽  
Female Ratio ◽  
Cutaneous Tuberculosis ◽  
Histopathological Features ◽  
Medical College ◽  
Histopathological Correlation ◽  
High Clinical Suspicion ◽  
Male To Female

<p class="abstract"><strong>Background:</strong> Cutaneous tuberculosis is a curable chronic infectious disease. The clinical presentation and histopathological interpretation of skin biopsy may show variations as various types of the disease exist. The clinical diagnosis should be confirmed by histopathological features before starting treatment for particular type of the disease.</p><p class="abstract"><strong>Methods:</strong> A retrospective hospital based study was conducted among patients in Chengalpattu medical college for last 3 years (May 2015 – April 2018) who had cutaneous tuberculosis. Skin biopsy taken from active lesion was stained with routine haematoxylin and eosin (H &amp; E) stain.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 20 cases, male to female ratio was 1.5:1. The age of the patients ranged from 11-68 years. Clinically, lupus vulgaris was the most common type of cutaneous tuberculosis with 35% cases followed by tuberculosis verrucosa cutis 20% cases, scrofuloderma 15% and atypical mycobacterial infections 10%, and least common types are lichen scrofulosorum 5% which correlates with the previous study of Aruna et al. Characteristic tuberculoid granulomas were seen in 71.4% cases of lupus vulgaris, all cases of scrofuloderma, lichen scrofulosorum and 80% of tuberculosis verrucosa cutis. The clinical and histopathological correlation was seen in 17 cases (85%).</p><p class="abstract"><strong>Conclusions:</strong> There can be overlap between different types of cutaneous tuberculosis with various other dermatological diseases, both clinically and morphologically and so correlation of clinical and histopathological features appears to be more useful for accurate diagnosis and typing of cutaneous tuberculosis. High clinical suspicion is necessary in cutaneous tuberculosis and early diagnosis and treatment are essential to prevent its complications.</p>

AUDIT OF LAPAROSCOPIC APPENDICECTOMY IN A SURGICAL UNIT.

2020 ◽  
Vol 7 (12) ◽  
pp. 1-5
Keyword(s):  
Laparoscopic Approach ◽  
Training Needs ◽  
Laparoscopic Appendicectomy ◽  
Academic Hospital ◽  
Female Ratio ◽  
Patient Demographics ◽  
Included Patient ◽  
Clinical Presentations ◽  
Male To Female ◽  
Surgical Unit

Background With the advent of laparoscopy, surgeons need new skills and must relearn the procedures that had been familiar in open surgery. For some procedures, like appendicectomy, the learning curve can be steep, owing to the diversity of clinical presentations and the different locations of the appendix. Laparoscopic appendicectomy is gaining momentum worldwide because of the purported benefits of minimal access. The implication is that surgical training needs to adjust accordingly to provide adequate skills to prospective surgeons. In this manuscript, we endeavor to review the practice of laparoscopic appendicectomy in our unit. Objective A two-year review of laparoscopic appendicectomy in a surgical unit to reflect on the stages of appendicitis at presentation, the percentage of procedures done laparoscopically, and the trainees’ contributions. Method Retrospective analysis of data prospectively collected between January 2013 and December 2014 in a surgical unit at the Chris Hani Baragwanath Academic Hospital (CHBAH), Johannesburg, South Africa. The parameters analyzed included patient demographics, surgical approach, intraoperative findings, and histopathological reports. Results The male to female ratio was 2:1, with a mean age of 25.7 years. The percentages of complicated, uncomplicated, and normal appendices, based on histopathological reports, were 53%, 20%, and 12%, respectively. Conclusion The laparoscopic approach represented 63% of all appendicectomies. More than half of the cases of appendicitis were complicated. Specialist surgeons performed most of the laparoscopic cases.

scholarly journals Alopecia areata in Black African patients: epidemiological, clinical, and therapeutic aspects

2021 ◽  
Vol 12 (1) ◽  
pp. 24-26
Author(s):  
Yao Isidore Kouassi ◽  
Koffi Kouamé Pacôme GBANDAMA
Keyword(s):  
Alopecia Areata ◽  
Systemic Treatment ◽  
Local Treatment ◽  
Young Male ◽  
University Hospital ◽  
Female Ratio ◽  
Black African ◽  
Plaque Type ◽  
African Patients ◽  
The University

Background: The aim was to describe the epidemiological, clinical, and therapeutic aspects of alopecia areata in Black African patients. Material and Methods: This was a retrospective descriptive study conducted at the Dermatology and Venerology Department of the University Hospital Center of Treichville over a 5-year. Results: The prevalence of alopecia areata was 0.2%. The mean age was 24.6 years and the male-to-female ratio was 1.47. Stress preceding the symptomatology was found in 3 cases. As for the clinical distribution, there were 25 cases of plaque-type alopecia areata, 10 cases of total descending alopecia areata, and 7 cases of universal alopecia areata. There was no nail damage and no associated pathologies. Local treatment only was administered in 31 cases, local and systemic treatment in 8 cases, and systemic treatment only in 3 cases. Conclusions: Alopecia areata predominates in young male populations and pathologies associated with alopecia are very rare.

scholarly journals Disparities between IgG4-related kidney disease and extrarenal IgG4-related disease in a case–control study based on 450 patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Qiaozhu Zeng ◽  
Jingyuan Gao ◽  
Xinyu Zhang ◽  
Aichun Liu ◽  
Zhenfan Wang ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Clinical Laboratory ◽  
Imaging Finding ◽  
Age At Onset ◽  
Female Ratio ◽  
Related Disease ◽  
Igg4 Related Disease ◽  
Peking University ◽  
Chinese Cohort ◽  
Male To Female

AbstractWe aimed to compare the demographic, clinical and laboratory characteristics between IgG4-related kidney disease (IgG4-RKD+) and extrarenal IgG4-related disease (IgG4-RKD−) in a large Chinese cohort, as well as describing the radiological and pathological features of IgG4-RKD+. We retrospectively analyzed the medical records of 470 IgG4-related disease (IgG4-RD) patients at Peking University People’s Hospital from January 2004 to January 2020. The demographic, clinical, laboratory, radiological and pathological characteristics between IgG4-RKD+ and IgG4-RKD− were compared. Twenty IgG4-RD patients who had definite etiology of renal impairment including diabetes, hypertension and etc. were excluded. Among the remained 450 IgG4-RD patients, 53 were diagnosed with IgG4-RKD+ . IgG4-RKD+ patients had older age at onset and at diagnosis. Male to female ratio of IgG4-RKD+ patients is significantly higher. In the IgG4-RKD+ group, the most commonly involved organs were salivary gland, lymph nodes and pancreas. It was found that renal function was impaired in approximately 40% of IgG4-RKD+ patients. The most common imaging finding is multiple, often bilateral, hypodense lesions. Male sex, more than three organs involved, and low serum C3 level were risk factors for IgG4-RKD+ in IgG4-RD patients. These findings indicate potential differences in pathogenesis of these two phenotypes.

scholarly journals P129 The utility of routine operative swab culture in uncomplicated peri-anal abscesses

BJS Open ◽  
2021 ◽  
Vol 5 (Supplement_1) ◽  
Author(s):  
Apoorva Khajuria ◽  
Tuba Rahim ◽  
Mariam Baig ◽  
Kai Leong ◽  
Apoorva Khajuria
Keyword(s):  
Inflammatory Bowel Disease ◽  
Perianal Abscess ◽  
Female Ratio ◽  
Incision And Drainage ◽  
Common Presentation ◽  
History Of ◽  
Inflammatory Bowel ◽  
Operative Findings ◽  
The Cost ◽  
Male To Female

Abstract Introduction Despite perianal abscess being a common presentation, certain aspects of its management remain controversial, especially the routine use of intra-operative swab cultures. Methods A retrospective review of patients that underwent incision and drainage procedures for a perianal abscess over a six-month period was undertaken. Results Over 6 months, 50 patients were identified. The male to female ratio was 3:1 and median ASA score was 1. Only 6/50 patients presented with recurrent abscess and 1 patient had history of inflammatory bowel disease. On the basis of operative findings, 39 patients (78%) had uncomplicated abscess (not associated with cellulitis, sinus or fistula); swab cultures were performed in 26 (67%) of these patients. All patients were discharged on the same day; microbiology reports did not impact the treatment and no patients were followed up in clinic post-operatively or presented with recurrence. The number of unnecessary microbiology swabs undertaken in this cohort equates to approximately 52 unnecessary swabs a year. The cost of one swab is £10.10p, which means £520 could potentially be saved annually. Conclusion Routine intra-operative swab cultures do not impact management decisions, add to unnecessary costs and therefore should not be undertaken in uncomplicated or first presentation of peri-anal abscesses.

scholarly journals High rates of gastroesophageal cancers in patients with dyspepsia undergoing upper gastrointestinal endoscopy in Uganda

2021 ◽  
Vol 09 (07) ◽  
pp. E997-E1000
Author(s):  
Ronald Mbiine ◽  
Cephas Nakanwagi ◽  
Olivia Kituuka
Keyword(s):  
Positive Association ◽  
Referral Hospital ◽  
Outcome Variable ◽  
Mulago Hospital ◽  
Upper Gastrointestinal Endoscopy ◽  
Female Ratio ◽  
Mulago National Referral Hospital ◽  
Male To Female ◽  
Upper Gastrointestinal ◽  
National Referral Hospital

Abstract Background and study aims Dyspepsia is the most common presenting symptom in the gastrointestinal clinic of Mulago National Referral hospital. The etiology is essentially not fully described in our patient population. This study was therefore conducted to establish the causes of dyspepsia based on endoscopic diagnosis among patients with dyspepsia seeking care at the National Referral hospital of Uganda. Patients and methods This retrospective study conducted in the endoscopy unit of Mulago hospital reviewed 356 patient endoscopy reports spanning January 2018 to July 2020 with a focus on those with a referral indication of dyspepsia. Age and sex were the independent variables of interest while the endoscopy findings as reported by the endoscopist were the outcome variable of interest. Results Of the 356 endoscopy reports reviewed, 159 met the inclusion criterion of dyspepsia as the indication. Participant mean age was 47.7 years (± 16.53) with the majority (25.79 %) in the fifth decade while the male to female ratio was 1. The majority of patients had organic dyspepsia (90.57 %) while the commonest finding was gastritis 69 (43.4 %). Gastroesophageal cancers represented (18) 11.32 % of all findings. There was a positive association between age > 50 years with gastroesophageal cancers (7.639) as well as age < 50 years and functional dyspepsia (2.794); however, all these were not statistically significant (P = 0.006 and (P = 0.095, respectively). Conclusions Organic/structural dyspepsia comprises over 90 % of investigated dyspepsia with 11 % comprising cancer among patients seeking endoscopy at the National Referral Hospital of Uganda.

Astrocytomas of the spinal cord in children and adolescents

1985 ◽  
Vol 63 (5) ◽  
pp. 669-675 ◽  
Author(s):  
Ronald Reimer ◽  
Burton M. Onofrio
Keyword(s):  
Spinal Cord ◽  
Histological Grade ◽  
Extended Period ◽  
Spinal Deformities ◽  
Duration Of Symptoms ◽  
Female Ratio ◽  
Content Type ◽  
Orthopedic Procedure ◽  
Male To Female ◽  
Fine Print

✓ The authors review 32 cases of spinal cord astrocytoma in patients under 20 years of age who were treated at the Mayo Clinic between 1955 and 1980. There was a 1.3:1 male to female ratio. Twenty patients were between 6 and 15 years of age at the time of diagnosis. The duration of symptoms prior to definitive diagnosis varied from 5 days to 9 years, with an average of 24 months. The most common symptoms were pain (62.5%), gait disturbance (43.7%), numbness (18.8%), and sphincteric dysfunction (18.8%). The most common neurological findings were a Babinski response (50.0%), posterior column sensory dysfunction (40.6%), and paraparesis (37.5%). A median follow-up period of 8.6 years (range 0.8 to 25.5 years) revealed that the survival time diminished with increased histological grade of the astrocytoma (p < 0.001). The development of postlaminectomy spinal deformities represented a serious postoperative complication. This occurred in 13 patients and was first recognized between 8 and 90 months postoperatively. Six deformities occurred following cervical laminectomy, and eight patients required at least one orthopedic procedure. It is crucial to follow these patients for an extended period of time to watch for postoperative spinal deformities.

scholarly journals Clinicohematological Study of Thrombocytosis in Children

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Nathiya Subramaniam ◽  
Suneel Mundkur ◽  
Pushpa Kini ◽  
Nalini Bhaskaranand ◽  
Shrikiran Aroor
Keyword(s):  
Platelet Count ◽  
Myeloid Leukemia ◽  
Prospective Observational Study ◽  
Myelogenous Leukemia ◽  
Distribution Width ◽  
Female Ratio ◽  
Reactive Thrombocytosis ◽  
Acute Myelogenous ◽  
Male To Female ◽  
Primary Thrombocytosis

Introduction. Primary thrombocytosis is very rare in children; reactive thrombocytosis is frequently observed in children with infections, anemia, and many other causes. Aims and Objectives. To identify the etiology of thrombocytosis in children and to analyze platelet indices (MPV, PDW, and PCT) in children with thrombocytosis. Study Design. A prospective observational study. Material and Methods. A total of 1000 patients with thrombocytosis (platelet > 400×109/L) were studied over a period of 2 years. Platelet distribution width (PDW), mean platelet volume (MPV), and plateletcrit (PCT) were noted. Results. Of 1000 patients, 99.8% had secondary thrombocytosis and only two children had primary thrombocytosis (chronic myeloid leukemia and acute myelogenous leukemia, M7). The majority of the children belonged to the age group of 1month to 2 years (39.7%) and male to female ratio was 1.6 : 1. Infection with anemia (48.3%) was the most common cause of secondary thrombocytosis followed by iron deficiency alone (17.2%) and infection alone (16.2%). Respiratory infection (28.3%) was the predominant infectious cause observed. Thrombocytosis was commonly associated with IDA among all causes of anemia and severity of thrombocytosis increased with severity of anemia (P=0.021). With increasing platelet count, there was a decrease in MPV (<0.001). Platelet count and mean PDW among children with infection and anemia were significantly higher than those among children with infection alone and anemia alone. None were observed to have thromboembolic manifestations. Conclusions. Primary thrombocytosis is extremely rare in children than secondary thrombocytosis. Infections in association with anemia are most commonly associated with reactive thrombocytosis and severity of thrombocytosis increases with severity of anemia.

Sign in / Sign up

Export Citation Format

Share Document