Clinical and endoscopic aspects of metastases to the gastrointestinal tract

Endoscopy ◽  
2019 ◽  
Vol 51 (07) ◽  
pp. 646-652 ◽  
Author(s):  
Luiza Haendchen Bento ◽  
Mauricio Kazuyoshi Minata ◽  
Clelma Pires Batista ◽  
Bruno da Costa Martins ◽  
Luciano Henrique Lenz Tolentino ◽  
...  
Keyword(s):  
Survival Rate ◽  
Palliative Treatment ◽  
Survival Rates ◽  
Case Series ◽  
Gastric Body ◽  
Gi Tract ◽  
Cancer Disease ◽  
Primary Tumors ◽  
The Mean ◽  
Single Center Observational Study

Abstract Background Studies that describe metastases to the gastrointestinal (GI) tract are restricted to small case series. An increase in the frequency of this condition is expected, so it would be useful to better characterize the endoscopic aspects of metastasis to the GI tract. The aims of this study were to describe the frequency and endoscopic features of the lesions, and to analyze the survival rate after diagnosis of metastasis. Methods This was a retrospective, single-center, observational study, conducted between 2009 and 2017. Patients with metastasis to the GI tract were included. Results 95 patients were included. Melanoma (25.3 %), lung (15.8 %), and breast (14.7 %) were the most frequent primary tumors. The most common endoscopic presentation was a solitary, ulcerated lesion in the gastric body. Conventional biopsy was diagnostic in 98.9 % of the cases. The mean and median survival rates were 13.3 months (95 % confidence interval [CI] 8.2 – 18.3) and 4.7 months (95 %CI 3.7 – 5.6), respectively. Palliative treatment with chemo- and/or radiotherapy after the diagnosis of the metastasis was related to a higher survival rate. Conclusions Melanoma, lung, and breast cancer were the most common primary tumors to metastasize to the GI tract. The endoscopic features could not predict the primary site of the tumor. The finding of metastasis in the GI tract is related to the final stage of the cancer disease but patients who received palliative treatment with chemo- and/or radiotherapy after diagnosis of GI metastasis had higher survival rates.

Demography of barren-ground grizzly bears

2003 ◽  
Vol 81 (2) ◽  
pp. 294-301 ◽  
Author(s):  
Philip D McLoughlin ◽  
Mitchell K Taylor ◽  
H Dean Cluff ◽  
Robert J Gau ◽  
Robert Mulders ◽  
...  
Keyword(s):  
Survival Rate ◽  
Litter Size ◽  
Birth Interval ◽  
Ursus Arctos ◽  
Survival Rates ◽  
Grizzly Bears ◽  
Adult Males ◽  
Barren Ground ◽  
Rate Of Increase ◽  
The Mean

Between May 1995 and June 1999, we equipped 81 barren-ground grizzly bears (Ursus arctos) with satellite radio collars within a study area of 235 000 km2, centred 400 km northeast of Yellowknife, Northwest Territories, Canada. We used data from radiotelemetry to estimate survival rates, reproductive parameters, and the finite rate of increase of the population (λ). The annual survival rate of adult females was estimated at 0.979 (95% confidence intervals (CI) = 0.955–0.998), while the survival rate of adult males was 0.986 (95% CI = 0.942–1.0). The cub survival rate was 0.737 (95% CI = 0.600–0.844) and the yearling survival rate was 0.683 (95% CI = 0.514–0.821). Cub litter size averaged 2.23 (SE = 0.13, n = 35), while yearling litter size decreased to a mean of 1.86 (SE = 0.12, n = 35). The mean litter size of females with 2-year-olds was 1.85 (SE = 0.15, n = 20). The mean birth interval was 2.8 years (SE = 0.3 years, n = 17). The mean reproductive interval, which is calculated by excluding the loss of whole litters from the sample, was 3.9 years (SE = 0.4 years, n = 9). Mean litter size divided by mean birth interval yielded an annual natality rate of 0.81 cubs per adult female per year. The mean age at first parturition was 8.1 years (SE = 0.5 years, n = 10). We believe the population to be currently stable or slightly increasing (λ = 1.033, 95% CI = 1.008–1.064).

scholarly journals Short Term Outcomes of Gastric Cancer at University Teaching Hospital of Kigali (CHUK), Rwanda.

2020 ◽  
Author(s):  
Irénée Niyongombwa ◽  
Irénée David Karenzi ◽  
Isaie Sibomana ◽  
Vital Muvunyi ◽  
Jean Marie Vianney Kagimbangabo ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Survival Rate ◽  
Mortality Rate ◽  
Hospital Mortality ◽  
Cox Regression ◽  
Advanced Disease ◽  
Survival Rates ◽  
University Teaching ◽  
Short Term ◽  
The Mean

Abstract Background: Gastric cancer is the 4th most common cause of cancer death worldwide with an annual global incidence of 985,600; two thirds of them being in the developing countries. Gastric cancer is endemic in the so called stomach cancer region comprising Rwanda, Burundi, South Western Uganda and eastern Kivu province of Democratic Republic of Congo and its incidence in Rwanda is estimated around 13 to 15 per 100,000 population. To date, the outcomes of gastric cancer in the East African region are under investigated, and the survival rate in Rwanda is not known. The aim of this study was to describe the short term outcomes (in-hospital mortality rate, length of hospital stay, 3, 6, 12 and 24 months survival rates) in patients treated for gastric cancer at CHUK.Methods: We retrospectively reviewed the data collected from records of patients who consulted CHUK over a period of 10 years from September 2007 to August 2016. Patients were followed in hospital and after discharge for survival length. Descriptive statistics were used for baseline demographic data, Kaplan-Meier model and univariate cox regression were used for survival analysis.Results: Of the 199 patients enrolled in the study, 92 (46%) were males and 107 (54%) females. The mean age was 55.4 ranging between 24 and 93. The mean symptoms duration was 15 months. Most patients consulted with advanced disease, 62.3% with distant metastases. Treatment with curative intent was offered for only 19.9% of patients. The in-hospital mortality rate was 13.3%. The 3, 6, 12 and 24 months survival rate was 52%, 40.5%, 28% and 23.4% respectively. The Overall survival rate was 7 months.Conclusion: Patients with gastric cancer have delayed consultations and advanced disease at the time of presentation. This cancer is associated with poor outcomes in terms of hospital mortality and post discharge survival rates.

The 1997 Report of the Japanese National Registry Data on Pediatric Peritoneal Dialysis Patients

1999 ◽  
Vol 19 (2_suppl) ◽  
pp. 473-478 ◽  
Author(s):  
Masataka Hondaa
Keyword(s):  
Peritoneal Dialysis ◽  
Survival Rate ◽  
Survival Rates ◽  
National Registry ◽  
Catheter Survival ◽  
Technique Survival ◽  
The Mean ◽  
National Registry Data ◽  
Patient Survival Rate

Objective We have collected data on pediatric patients less than 16 years of age from the National Registry of Chronic Peritoneal Dialysis (PD). We present our experience with this population. Design The database details the patient numbers, age, outcome, cause of death, reason for terminating PD therapy, type of PD therapy, peritonitis, and catheter survival. Patients Of 807 patients, 70 patients (8.7%) were under 1 year of age, and 268 patients (33.2%) were under 6 years of age, clearly indicating that PD was the treatment of choice in young children. The duration on PD was 5 years or more in 200 patients (24.8%), which showed an increase in long-term PD patients from 11% in 1991. Patients on automated PD (APD) increased to 75% in 1997 from 9% in 1991. Results The outcomes for the total patient population of 807 as of the end of 1997 is: 253 patients (31.4%) were being successfully treated with PD, 87 patients (10.8%) died, 238 patients (29.5%) received a kidney transplant, and 121 (15.0%) were transferred to hemodialysis. The patient survival rate was 91% in 3 years and 86% in 5 years. The technique survival rate was 83% in 3 years and 71% in 5 years. The rate of peritonitis was 1 episode per 30 patient -months. The mean catheter duration was 2.25 years. Conclusion The patient and technique survival rates, the peritonitis rate, and the catheter survival improved recently. However, these data were worse in younger children (less than 6 years of age), indicating that extra-careful management is needed for this young age group.

Overestimation of the Effectiveness of Cardiopulmonary Resuscitation

1997 ◽  
Vol 84 (3_suppl) ◽  
pp. 1409-1410 ◽  
Author(s):  
Nathan M. Kostoulakos ◽  
Drake R. Bradley
Keyword(s):  
College Students ◽  
Survival Rate ◽  
Cardiopulmonary Resuscitation ◽  
Survival Rates ◽  
The Mean ◽  
Actual Survival

38 college students estimated the survival rates of people administered cardiopulmonary resuscitation. The mean estimated survival rate (54.5%) was significantly higher than the actual survival rate (10%).

Twenty Years of Renal Transplantation in Children

PEDIATRICS ◽  
1986 ◽  
Vol 77 (4) ◽  
pp. 465-470
Author(s):  
Donald Potter ◽  
Nicholas Feduska ◽  
Juliet Melzer ◽  
Marvin Garovoy ◽  
Susan Hopper ◽  
...  
Keyword(s):  
Overall Survival ◽  
Renal Transplantation ◽  
Survival Rate ◽  
Living Donor ◽  
Patient Survival ◽  
Survival Rates ◽  
Overall Survival Rate ◽  
Creatinine Concentration ◽  
The Mean ◽  
Cadaver Donor

Two-hundred three children 1 to 16 years of age received kidney transplants during a 20-year period, 100 from living donors and 103 from cadaver donors. The overall survival rate was 79%. Actuarial patient and kidney survival rates at 15 years were 79% and 52%, respectively, for recipients of living donor kidneys and 57% and 19%, respectively, for recipients of cadaver donor kidneys. One of two children who received transplants in 1964 was alive 20½ years later. Twenty-nine children had kidneys that had functioned more than 10 years; their mean serum creatinine concentration was 1.7 mg/dL and 24 were fully rehabilitated. Eighteen were more than 2 SD below the mean height of normal chidren, however. Comparison of survival rates during successive 5-year intervals showed significant improvement in patient survival during the 20-year period and smaller improvements in kidney survival after 1979. Patient survival after living donor transplants during the last 10 years was 100%, and kidney survival during the last 5 years was 92%. Improvement was attributed to the effect of experience, as well as to changes in immunosuppressive therapy in 1972 and the introduction of donor-specific transfusions in 1978.

Therapeutic Management of Pyriform Sinus Cancer: Results of a Single-Center Study of 122 Patients

2017 ◽  
Vol 156 (3) ◽  
pp. 498-503 ◽  
Author(s):  
Jérôme Donnadieu ◽  
Nathalie Klopp-Dutote ◽  
Aurélie Biet-Hornstein ◽  
Vladimir Strunski ◽  
Geoffrey Mortuaire ◽  
...  
Keyword(s):  
Overall Survival ◽  
Survival Rate ◽  
Median Survival ◽  
Survival Rates ◽  
Case Series ◽  
Pyriform Sinus ◽  
Therapeutic Management ◽  
Stage 4 ◽  
Sinus Cancer ◽  
Overall Survival Rates

Objective To analyze the survival rate of a nonselected pyriform sinus cancer population. Study Design Case series with chart review. Setting University hospital. Subjects and Methods A total of 122 patients were included in this study covering the 2002-2008 period. All patients had squamous cell carcinoma originating from the pyriform sinus. Survival and prognostic factors were analyzed. Results The 3- and 5-year overall survival rates were 39.7% and 2.4%, respectively. The 3- and 5-year survival rates without recurrence were 34% and 27%, respectively. The median survival rates by UICC stage were as follows: stage 1 and 2 patients, 60 months; stage 3, 40 months; stage 4, 19 months. Stage 4 patients had a lower median survival rate than other stages ( P = .039). The 5-year survival rate was 46% for patients having T3-T4 operable cancers treated by surgery vs 45% for patients treated by laryngeal conservation protocol (not significant). The 5-year survival rate for patients having nonoperable T4 cancers was 17.2%. The 3- and 5-year overall survival rates of N0 patients was significantly higher than N1 patients ( P = .042). N2 and N3 patients had 100% 5-year mortality. Conclusion This study showed that overall survival and therapeutic management depend on the initial stage of pyriform sinus cancer, notably on the N status. In particular, nonoperable T4 pyriform sinus cancer and N2 and N3 patients had a very poor prognosis. A laryngeal conservation protocol seemed as effective as surgical management in terms of survival.

Malignant melanoma of the vulva: clinicopathological features

1991 ◽  
Vol 1 (2) ◽  
pp. 81-87 ◽  
Author(s):  
K. Blessing ◽  
N. M. Kernohan ◽  
I. D. Miller ◽  
A. I. Al Nafussi
Keyword(s):  
Lymph Node ◽  
Surgical Treatment ◽  
Survival Rate ◽  
Malignant Melanoma ◽  
Palliative Treatment ◽  
Elderly Women ◽  
Clinicopathological Features ◽  
Node Dissection ◽  
The Mean ◽  
Radical Vulvectomy

From the files of the Scottish Melanoma Group, we have identified 41 cases of vulval malignant melanoma, which represents 1.7% of all the melanomas occurring in women in Scotland, during the period 1979–1989. Thirty-seven were aged 50 years or older with the mean age being 70 years. The average Breslow depth of the lesions was 6.0 mm, with 29 being greater than 3.0 mm in depth. Nineteen cases were polypoidal and 37 were ulcerated. Six patients had radical vulvectomy with lymph node dissection, three had biopsy and palliative treatment, and the majority of the remaining patients had local excision only, with surgical margins of less than 2 cm. The 5-year survival rate (available for 23 patients) is 21.7%, compared to 72% for cutaneous melanoma in females, in general, in the same population. In this series, the survival rate is poor, as the lesions occurred in elderly women and the melanomas were thick at presentation. Surgical treatment appears to have been rather conservative in those who were dead from their disease at 5 years.

scholarly journals No difference of survival between cruciate retaining and substitution designs in high flexion total knee arthroplasty

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Gun-Woo Kim ◽  
Quan He Jin ◽  
Jun-Hyuk Lim ◽  
Eun-Kyoo Song ◽  
Jong-Keun Seon
Keyword(s):  
Survival Rate ◽  
Survival Rates ◽  
Cruciate Retaining ◽  
High Flexion ◽  
Significant Difference ◽  
Ankle Angle ◽  
Total Knee ◽  
The Mean ◽  
Hip Knee Ankle Angle

AbstractThe aim of this study was to compare the long-term implant survival and outcomes in patients with high-flexion cruciate-retaining (CR) or high-flexion posterior cruciate-substituting (PS) knee implants. A total of 253 knees (CR group: 159 vs. PS group: 94) were available for examination over a mean follow-up of 10 years. Clinical outcomes were assessed including the Hospital for Special Surgery score, Knee Society score and Western Ontario and McMaster Universities Osteoarthritis Index score at the final follow-up. Radiologic measurements were also assessed including the hip-knee-ankle angle and radiolucent lines according to the KSS system at the final follow-up. The survival rate was analyzed using the Kaplan–Meier method. At the final follow-up, the mean total HSS scores were similar between the two groups (p = 0.970). The mean hip-knee-ankle angle at the final follow-up was similar between groups (p = 0.601). The 10- and 15-year survival rates were 95.4% and 93.3% in the CR group and 92.7% and 90.9% in the PS group, respectively, with no significant difference. Similar clinical and radiographic outcomes could be achieved with both the high-flexion CR and high-flexion PS total knee designs without a difference in survival rate after a 10-year follow-up.

scholarly journals Short Term Outcomes of Gastric Cancer at University Teaching Hospital of Kigali (CHUK), Rwanda.

2021 ◽  
Author(s):  
Irénée Niyongombwa ◽  
Irénée David Karenzi ◽  
Isaie Sibomana ◽  
Vital Muvunyi ◽  
Jean Marie Vianney Kagimbangabo ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Survival Rate ◽  
Mortality Rate ◽  
Hospital Mortality ◽  
Cox Regression ◽  
Advanced Disease ◽  
Survival Rates ◽  
University Teaching ◽  
Short Term ◽  
The Mean

Abstract Purpose: Gastric cancer is endemic in the so called stomach cancer region comprising Rwanda, Burundi, South Western Uganda and eastern Kivu province of Democratic Republic of Congo but its outcomes in that region are under investigated. This is the first study ever conducted in Rwanda with the purpose to describe the short term outcomes (in-hospital mortality rate, length of hospital stay, 3, 6, 12 and 24 months survival rates) in patients treated for gastric cancer. Methods: We retrospectively reviewed the data collected from records of patients who consulted CHUK over a period of 10 years from September 2007 to August 2016. Patients were followed in hospital and after discharge for survival length. Descriptive statistics were used for baseline demographic data, Kaplan-Meier model and univariate cox regression were used for survival analysis. Results: Of the 199 patients enrolled in the study, 92 (46%) were males and 107 (54%) females. The mean age was 55.4 ranging between 24 and 93. The mean symptoms duration was 15 months. Most patients consulted with advanced disease, 62.3% with distant metastases. Treatment with curative intent was offered for only 19.9% of patients. The in-hospital mortality rate was 13.3%. The 3, 6, 12 and 24 months survival rate was 52%, 40.5%, 28% and 23.4% respectively. The Overall survival rate was 7 months. Conclusion: In Rwanda, patients with gastric cancer have delayed consultations and advanced disease at the time of presentation. This cancer is associated with poor outcomes in terms of hospital mortality and post discharge survival rates.

scholarly journals Five-Year Prospective Study on Implant Failure and Marginal Bone Remodeling Expected Using Bone Level Implants with Sandblasted/Acid-Etched Surface and Conical Connection

2022 ◽  
Author(s):  
Marco Tallarico ◽  
Aurea Maria Immacolata Lumbau ◽  
Silvio Mario Meloni ◽  
Irene Ieria ◽  
Chang-Joo Park ◽  
...  
Keyword(s):  
Survival Rate ◽  
Bone Remodeling ◽  
Case Series ◽  
Insertion Torque ◽  
Implant Survival ◽  
Bone Level ◽  
The Mean ◽  
Prospective Case Series ◽  
Gingival Biotype

Abstract Objective The purpose of the present prospective, case-series study was to report implant survival rate and marginal bone remodeling expected 5 years after loading using dental implants placed in daily practice. Materials and Methods This research was designed as an open-cohort, prospective, case-series evaluation. Any partially or completely edentulous patient, scheduled to receive at least one bone level implant, was considered eligible for this study. Primary outcome measurements were: implant and prosthetic cumulative survival rate and any complications experienced up to the 5-year follow-up. Secondary outcome measures were: thickness of gingival biotype, implant insertion torque, implant stability quotient, and marginal bone loss (MBL). Results Ninety consecutive patients (34 males and 56 females, aged between 24 and 81 years old [mean: 53.2 ± 15.4]) with 243 inserted implants were followed for at least 5 years after loading (mean: 65.4 ± 3.1 months; range from 60 to 72). At the 1-year follow-up, no drop-outs were recorded, but 17 patients (18.9%) with 18 restorations (12.6%) delivered on 34 implants (14%) were lost at the 5-year examination. At the 5-year follow-up examination, six implants lost osseointegration (97.5%). In the same period, four prostheses failed (97.2%). Five complications were reported in five different patients (prosthetic success rate was 96.5%, at patient level). Five years after loading, the mean MBL was 0.41 ± 0.30 mm. The difference from the 1-year data was 0.04 ± 0.19 mm. A statistically significant higher MBL was found for smokers, and patients with thin gingival biotype. The mean implant insertion torque was 42.9 ± 4.8 Ncm (range from 15 to 45 Ncm). Two-hundred and three implants (83.5%) were inserted with an insertion torque ≥35 and ≤45 Ncm. Conclusions High implant survival and success rate could be expected with stable marginal bone remodeling up to 5 years after loading. Smoking and thin tissue biotype were the most important variabilities associated with higher MBL. Further research studies are needed to confirm these results.

Sign in / Sign up

Export Citation Format

Share Document