Endoscopic ischemic polypectomy for small-bowel polyps in patients with Peutz–Jeghers syndrome

Endoscopy ◽  
2020 ◽  
Author(s):  
Tsevelnorov Khurelbaatar ◽  
Hirotsugu Sakamoto ◽  
Tomonori Yano ◽  
Yuichi Sagara ◽  
Ulzii Dashnyam ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Small Bowel ◽  
Median Number ◽  
Friedman Test ◽  
Double Balloon Endoscopy ◽  
Risk Of Bleeding ◽  
Peutz Jeghers Syndrome ◽  
Mild Acute Pancreatitis ◽  
Over Time ◽  
Observation Period

Abstract Background To decrease the risk of bleeding or perforation, ischemic polypectomy is performed using a detachable snare or endoclip with double-balloon endoscopy (DBE) for small-bowel polyps in patients with Peutz – Jeghers syndrome. The aim of this study was to determine the effectiveness and feasibility of ischemic polypectomy. Methods We retrospectively reviewed patients who underwent two or more sessions of ischemic polypectomy using DBE from July 2004 to August 2017. Results 67 therapeutic DBEs were performed in nine patients during the study period and 352 polyps were treated. The median observation period was 34 months (range 12 – 66). There was a declining trend over time in the median number of polyps > 15 mm treated per patient first DBE session 6, second 2, third 1.5, fourth 0.5, fifth 0.5; P = 0.11, Friedman test). No patient required laparotomy due to intussusception during the study period. One patient developed mild acute pancreatitis after the procedure. Conclusions Ischemic polypectomy was feasible for the control of small-bowel polyps in patients with Peutz – Jeghers syndrome.

Nonsurgical management of small-bowel polyps in Peutz–Jeghers syndrome with extensive polypectomy by using double-balloon endoscopy

2011 ◽  
Vol 74 (2) ◽  
pp. 328-333 ◽  
Author(s):  
Hirotsugu Sakamoto ◽  
Hironori Yamamoto ◽  
Yoshikazu Hayashi ◽  
Tomonori Yano ◽  
Tomohiko Miyata ◽  
...  
Keyword(s):  
Small Bowel ◽  
Double Balloon Endoscopy ◽  
Double Balloon ◽  
Nonsurgical Management ◽  
Peutz Jeghers Syndrome

Tu1567 Nonsurgical Management of Small Bowel Polyps in Peutz-Jeghers Syndrome With Extensive Polypectomy Using Double-Balloon Endoscopy

2011 ◽  
Vol 73 (4) ◽  
pp. AB449
Author(s):  
Hirotsugu Sakamoto ◽  
Hironori Yamamoto ◽  
Yoshikazu Hayashi ◽  
Tomonori Yano ◽  
Tomohiko Miyata ◽  
...  
Keyword(s):  
Small Bowel ◽  
Double Balloon Endoscopy ◽  
Double Balloon ◽  
Nonsurgical Management ◽  
Peutz Jeghers Syndrome

Double-balloon endoscopy facilitates efficient endoscopic resection of duodenal and jejunal polyps in patients with familial adenomatous polyposis

Endoscopy ◽  
2020 ◽  
Author(s):  
Mariko Sekiya ◽  
Hirotsugu Sakamoto ◽  
Tomonori Yano ◽  
Shoko Miyahara ◽  
Manabu Nagayama ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Familial Adenomatous Polyposis ◽  
Endoscopic Resection ◽  
Adenomatous Polyposis ◽  
Long Term Outcomes ◽  
Double Balloon Endoscopy ◽  
Delayed Bleeding ◽  
Double Balloon ◽  
Observation Period

<b>Background</b> Many patients with familial adenomatous polyposis (FAP) have adenomatous polyps of the duodenum and the jejunum. We aimed to elucidate the long-term outcomes after double-balloon endoscopy (DBE)-assisted endoscopic resection of duodenal and jejunal polyps in patients with FAP. <b>Methods</b> We retrospectively reviewed patients who underwent more than two sessions of endoscopic resection using DBE from August 2004 to July 2018. <b>Results</b> A total of 72 DBEs were performed in eight patients (median 30 years old, range 12-53, 1.4 DBE procedures/patient-year) during the study period and 1237 polyps were resected. The median observation period was 77.5 months (range 8 to 167). There were 11 adverse events, including 7 with delayed bleeding and 4 with acute pancreatitis. No delayed bleeding occurred after cold polypectomy. Although one endoscopically-resected polyp in the duodenum was diagnosed as intramucosal carcinoma in one patient, no patient developed an advanced duodenal or jejunal cancer during the study period. <b>Conclusions</b> Endoscopic resection of duodenal and jejunal polyposis using DBE in patients with FAP can be performed safely, efficiently and effectively.

W1617: Management of Small Bowel Polyps in Peutz-Jeghers Syndrome by Using Fluoroscopic Enteroclysis, Double-Balloon Endoscopy, and Videocapsule Endoscopy

2010 ◽  
Vol 71 (5) ◽  
pp. AB373-AB374
Author(s):  
Naoki Ohmiya ◽  
Masanao Nakamura ◽  
Hiroyuki Takenaka ◽  
Kenji Morishima ◽  
Takeshi Yamamura ◽  
...  
Keyword(s):  
Small Bowel ◽  
Double Balloon Endoscopy ◽  
Double Balloon ◽  
Videocapsule Endoscopy ◽  
Peutz Jeghers Syndrome

scholarly journals A246 THE GLOBAL INCIDENCE OF ACUTE PANCREATITIS IS INCREASING OVER TIME: A SYSTEMATIC REVIEW AND META-ANALYSIS

2021 ◽  
Vol 4 (Supplement_1) ◽  
pp. 304-306
Author(s):  
J Iannuzzi ◽  
J H Leong ◽  
J Quan ◽  
J A King ◽  
J W Windsor ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Data Extraction ◽  
Meta Analysis ◽  
Temporal Trends ◽  
Western World ◽  
Common Disease ◽  
Biliary Disease ◽  
Comprehensive Overview ◽  
Annual Percent Change ◽  
Over Time

Abstract Background Acute pancreatitis is a common disease with significant associated morbidity and mortality. Historically, acute pancreatitis has been considered a disease with multiple etiologies and risk factors but is driven by alcohol and biliary disease. Multiple studies have shown that the incidence of acute pancreatitis is increasing globally among both adults and children. Aims The purpose of this study was to assess temporal trends in incidence of acute pancreatitis globally. Methods We performed a systematic literature search to identify population-based studies reporting the annual incidence of acute pancreatitis. Abstracts were independently assessed in duplicate to identify applicable papers for full-text review and data extraction. Joinpoint temporal trend analyses were performed to calculate the average annual percent change (AAPC) with 95% confidence intervals (CI). The AAPCs were pooled in a meta-analysis to capture the overall and regional trends in acute pancreatitis incidence over time. Temporal data were summarized in a static map and an interactive, web-based map to illustrate global differences. Results Forty-five studies reported the temporal incidence of acute pancreatitis (static map provided, online interactive map: https://kaplan-acute-pancreatitis-ucalgary.hub.arcgis.com/). The incidence of acute pancreatitis has increased from 1961 to 2016 (AAPC = 2.89%; 95% CI: 2.26, 3.52; n=41). Increasing incidence was observed in North America (AAPC = 2.71%; 95% CI: 1.93, 3.50; n=10) and Europe (AAPC = 2.79%; 95% CI: 1.95, 3.63; n=24). The incidence of acute pancreatitis was stable in Asia (AAPC = −0.28%; 95% CI: −5.03, 4.47; n=2). Conclusions This meta-analysis provides a comprehensive overview of the global incidence of acute pancreatitis over the last five decades and demonstrates a steadily rising incidence over time in most countries of the Western world. More studies are needed to better define the changing incidence of acute pancreatitis in Asia, Africa and Latin America. Funding Agencies None

Double-balloon endoscopy as the primary method for small-bowel video capsule endoscope retrieval

2010 ◽  
Vol 71 (3) ◽  
pp. 535-541 ◽  
Author(s):  
Stijn J.B. Van Weyenberg ◽  
Sietze T. Van Turenhout ◽  
Gerd Bouma ◽  
Jan Hein T.M. Van Waesberghe ◽  
Donald L. Van der Peet ◽  
...  
Keyword(s):  
Small Bowel ◽  
Capsule Endoscope ◽  
Primary Method ◽  
Double Balloon Endoscopy ◽  
Double Balloon

scholarly journals Clinical and therapeutic correlations in patients with slight acute pancreatitis

2015 ◽  
Vol 28 (1) ◽  
pp. 24-27 ◽  
Author(s):  
Clewis Henri MUNHOZ-FILHO ◽  
Fernando BATIGÁLIA ◽  
Hamilton Luiz Xavier FUNES
Keyword(s):  
Acute Pancreatitis ◽  
Intensive Care ◽  
Vital Signs ◽  
Positive Association ◽  
Multiple Organ ◽  
Glutamic Oxaloacetic Transaminase ◽  
Serum Glutamic Oxaloacetic Transaminase ◽  
Early Return ◽  
Lower Spectrum ◽  
Mild Acute Pancreatitis

BACKGROUND: Acute pancreatitis is an inflammatory disease of the pancreas due to enzymatic autodigestion which can cause necrosis or multiple organ failure; its pathophysiology is not fully known yet. AIM: To evaluate the correlation between clinical and therapeutic data in patients with mild acute pancreatitis. METHODS: A retrospective study in 55 medical records of patients admitted with acute mild pancreatitis was realized to analyze the association between age, leukocytosis, serum glutamic-oxaloacetic transaminase and lactate dehydrogenase, glucose, antibiotics, time admission and Ranson´s scores. RESULTS: There was a positive association between less intensive care (strict hydration, analgesia and monitoring of vital signs), early antibiotic therapy (monotherapy), early return to diet after 48 hours and laboratory control of the serum amylase and lipase (high in the first week and decreasing after 10 days, without any prognostic value). CONCLUSIONS: Changes in the management of patients with mild acute pancreatitis, such as enteral nutrition, rational use of lower spectrum antibiotics and intensive care, have contributed significantly to the reduction of hospitalization time and mortality.

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