Glass-laser in skin resurfacing

2022 ◽  
Author(s):  
Dario Bertossi ◽  
Luca Carletta ◽  
Laetitia Colombo Fink ◽  
Marco Bartolucci ◽  
Gianfranco Barba ◽  
...  
Keyword(s):  
Energy Levels ◽  
Laser System ◽  
Clinical Effectiveness ◽  
Clinical Applications ◽  
Surrounding Tissue ◽  
Glass Laser ◽  
Medical Laser ◽  
Skin Resurfacing ◽  
Skin Rejuvenation ◽  
Wide Range

Following our survey, we can appreciate that a variety of laser platforms exist to rejuvenate the skin by resurfacing the outer layer of the skin as well as heating the lower layers of the dermis. Based on reliable clinical effectiveness and a limited side effect profile, we can confirm that non-ablative fractionated technologies greatly improve the appearance of lentigines, rhytids, eliminate sun damage, attenuate scarring due to acne and other causes and treat hyper-pigmentation. The Fraxel® (Solta Medical) laser system delivers pulses across a wide range of density and energy levels. We determined that when increasing the pulse energy this led to an increase in thermolysis micro zone (MTZ) depth and width without damaging the surrounding tissue. Due to its performance and various clinical applications, Fraxel® Laser can be optimally considered to be the gold-standard for skin rejuvenation.

scholarly journals Assessment of Laser Effects on Skin Rejuvenation

2020 ◽  
Vol 11 (2) ◽  
pp. 212-219 ◽  
Author(s):  
Hazhir Heidari Beigvand ◽  
Mohammadreza Razzaghi ◽  
Mohammad Rostami-Nejad ◽  
Majid Rezaei-Tavirani ◽  
Saeed Safari ◽  
...  
Keyword(s):  
Biological Effects ◽  
Proteomics Data ◽  
Skin Resurfacing ◽  
Skin Rejuvenation ◽  
The Past ◽  
Biological Responses ◽  
Wide Range ◽  
Safety Considerations ◽  
Altered Proteins ◽  
Shock Proteins

Laser skin resurfacing has changed the approach of facial skin rejuvenation over the past decade. This article evaluates the laser effects on skin rejuvenation by the assessment of laser characteristics and histological and molecular changes, accompanied by the expression of proteins during and after laser-assisted rejuvenation of skin. It is important to note that different layers of skin with different cells are normally exposed to the sun’s UV radiation which is the most likely factor in aging and damaging healthy skin. To identify the expression of proteins, using validated databases and reviewing existing data could reveal altered proteins which could be analyzed and mapped to investigate their expression and their different effects on cell biological responses. In this regard, proteomics data can be used for better investigation of the changes in the proteomic profile of the treated skin. Different assessments have revealed the survival and activation of fibroblasts and new keratinocytes with an increase of collagen and elastin fibers in the dermis and the reduction of matrix metalloproteinases (MMPs) and heat shock proteins (HSPs) as a result of different lowpower laser therapies of skin. There are a wide range of biological effects associated with laser application in skin rejuvenation; therefore, more safety considerations should be regarded in the application of lasers in skin rejuvenation.

scholarly journals Light- and Melanin Nanoparticle-Induced Cytotoxicity in Metastatic Cancer Cells

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 965
Author(s):  
Victoria R. Gabriele ◽  
Robabeh M. Mazhabi ◽  
Natalie Alexander ◽  
Purna Mukherjee ◽  
Thomas N. Seyfried ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Metastatic Cancer ◽  
Energy Levels ◽  
Nanoparticle Concentration ◽  
Visible Radiation ◽  
Laser Illumination ◽  
Wide Range ◽  
Low Glucose ◽  
Melanin Nanoparticles ◽  
Metastatic Cancer Cells

Melanin nanoparticles are known to be biologically benign to human cells for a wide range of concentrations in a high glucose culture nutrition. Here, we show cytotoxic behavior at high nanoparticle and low glucose concentrations, as well as at low nanoparticle concentration under exposure to (nonionizing) visible radiation. To study these effects in detail, we developed highly monodispersed melanin nanoparticles (both uncoated and glucose-coated). In order to study the effect of significant cellular uptake of these nanoparticles, we employed three cancer cell lines: VM-M3, A375 (derived from melanoma), and HeLa, all known to exhibit strong macrophagic character, i.e., strong nanoparticle uptake through phagocytic ingestion. Our main observations are: (i) metastatic VM-M3 cancer cells massively ingest melanin nanoparticles (mNPs); (ii) the observed ingestion is enhanced by coating mNPs with glucose; (iii) after a certain level of mNP ingestion, the metastatic cancer cells studied here are observed to die—glucose coating appears to slow that process; (iv) cells that accumulate mNPs are much more susceptible to killing by laser illumination than cells that do not accumulate mNPs; and (v) non-metastatic VM-NM1 cancer cells also studied in this work do not ingest the mNPs, and remain unaffected after receiving identical optical energy levels and doses. Results of this study could lead to the development of a therapy for control of metastatic stages of cancer.

scholarly journals Platelet-Rich Plasma: Principles and Applications in Plastic Surgery

2019 ◽  
Vol 33 (03) ◽  
pp. 155-161 ◽  
Author(s):  
Amjed Abu-Ghname ◽  
Aurelia Trisliana Perdanasari ◽  
Matthew J. Davis ◽  
Edward M. Reece
Keyword(s):  
Plastic Surgery ◽  
Platelet Rich Plasma ◽  
New Technology ◽  
Clinical Applications ◽  
Great Promise ◽  
Clinical Settings ◽  
Skin Rejuvenation ◽  
Basic Principles ◽  
Reconstructive Plastic Surgery ◽  
Reconstructive Plastic

AbstractPlatelet-rich plasma (PRP) is an autogenously harvested liquid platelet concentrate extracted from a patient's peripheral blood that contains higher than baseline concentrations of growth factors and cytokines. This innovative new technology has demonstrated great promise in the field of plastic surgery, and its use has been evaluated in several clinical settings including wound healing, hair restoration, and skin rejuvenation. The goal of this article is to explain the biology behind PRP and to review the basic principles involved in its preparation. This will be followed by a discussion of some clinical applications of PRP in both aesthetic and reconstructive plastic surgery.

Multiterawatt picosecond Nd-glass laser system at 1053 nm

1990 ◽  
Vol 75 (3-4) ◽  
pp. 278-282 ◽  
Author(s):  
M. Ferray ◽  
L.A. Lompré ◽  
O. Gobert ◽  
A. L'huillier ◽  
G. Mainfray ◽  
...  
Keyword(s):  
Laser System ◽  
Glass Laser

Growth responses in red deer hinds from 16-24 months of age when fed two energy levels during their second winter

1998 ◽  
Vol 1998 ◽  
pp. 141-141
Author(s):  
M H Davies ◽  
D W Deakin
Keyword(s):  
Growth Response ◽  
Red Deer ◽  
Energy Levels ◽  
Growth Restriction ◽  
Growth Responses ◽  
Wide Range ◽  
Feeding Regimes ◽  
Cost Of Production ◽  
Red Meats

It is important that venison competes with other red meats in efficiency and cost of production. The growth responses of farmed red deer during the first 15-18 months of life have been well defined under a wide range of feeding and daylength regimes (Davies, 1995). However there is a need to examine less intensive systems of production which aim to maximise growth from grazed grass, following various growth-restriction feeding regimes during winter. The objective of this experiment was to quantify the growth response in 16-24 month old hinds fed two contrasting feeding regimes during their second winter, followed by a period at pasture.

Treatment of Arrhythmias by Radiofrequency Ablation

2013 ◽  
Author(s):  
M. Erol Ulucakli ◽  
Evan P. Sheehan
Keyword(s):  
Radiofrequency Ablation ◽  
Cardiac Tissue ◽  
Clinical Applications ◽  
Bioheat Transfer ◽  
Temperature Profiles ◽  
Cellular Injury ◽  
Rf Ablation ◽  
Transcatheter Therapy ◽  
Wide Range ◽  
Primary Modality

Radiofrequency ablation may be described as a thermal strategy to destroy tissue by increasing its temperature and causing irreversible cellular injury. Radiofrequency ablation is a relatively new modality which has found use in a wide range of medical applications and gained acceptance. RF ablation has been used to destroy tumors in the liver, prostate, breasts, lungs, kidneys, bones, and eyes. One of the early clinical applications was its use in treating supraventricular arrhythmias by selectively destroying cardiac tissue. Radiofrequency ablation has become established as the primary modality of transcatheter therapy for the treatment of symptomatic arrhythmias. Radiofrequency catheter ablation of cardiac arrhythmias was investigated using a finite-element based solution of the bioheat transfer equation. Spatial and temporal temperature profiles in the cardiac tissue were visualized.

scholarly journals The "Lung": a software-controlled air accumulator for quasi-continuous multi-point measurement of agricultural greenhouse gases

2011 ◽  
Vol 4 (10) ◽  
pp. 2293-2303 ◽  
Author(s):  
R. J. Martin ◽  
A. M. Bromley ◽  
M. J. Harvey ◽  
R. C. Moss ◽  
E. Pattey ◽  
...  
Keyword(s):  
Sequential Analysis ◽  
Laser System ◽  
N2o Emissions ◽  
Discrete Sample ◽  
Measuring Surface ◽  
Wide Range ◽  
Current Design ◽  
Tuneable Diode Laser ◽  
N2o Fluxes ◽  
Continuous Field

Abstract. We describe the design and testing of a flexible bag ("Lung") accumulator attached to a gas chromatographic (GC) analyzer capable of measuring surface-atmosphere greenhouse gas exchange fluxes in a wide range of environmental/agricultural settings. In the design presented here, the Lung can collect up to three gas samples concurrently, each accumulated into a Tedlar bag over a period of 20 min or longer. Toggling collection between 2 sets of 3 bags enables quasi-continuous collection with sequential analysis and discarding of sample residues. The Lung thus provides a flexible "front end" collection system for interfacing to a GC or alternative analyzer and has been used in 2 main types of application. Firstly, it has been applied to micrometeorological assessment of paddock-scale N2O fluxes, discussed here. Secondly, it has been used for the automation of concurrent emission assessment from three sheep housed in metabolic crates with gas tracer addition and sampling multiplexed to a single GC. The Lung allows the same GC equipment used in laboratory discrete sample analysis to be deployed for continuous field measurement. Continuity of measurement enables spatially-averaged N2O fluxes in particular to be determined with greater accuracy, given the highly heterogeneous and episodic nature of N2O emissions. We present a detailed evaluation of the micrometeorological flux estimation alongside an independent tuneable diode laser system, reporting excellent agreement between flux estimates based on downwind vertical concentration differences. Whilst the current design is based around triplet bag sets, the basic design could be scaled up to a larger number of inlets or bags and less frequent analysis (longer accumulation times) where a greater number of sampling points are required.

Inner-product theory calculations for some rational potentials in a three-dimensional system

1996 ◽  
Vol 74 (1-2) ◽  
pp. 4-9
Author(s):  
M. R. M. Witwit
Keyword(s):  
Energy Levels ◽  
Three Dimensional ◽  
Inner Product ◽  
Dimensional System ◽  
Product Technique ◽  
Special Cases ◽  
Wide Range ◽  
Perturbation Parameters ◽  
Three Dimensional System ◽  
Range Of Values

The energy levels of a three-dimensional system are calculated for the rational potentials,[Formula: see text]using the inner-product technique over a wide range of values of the perturbation parameters (λ, g) and for various eigenstates. The numerical results for some special cases agree with those of previous workers where available.

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