Secondary metabolites from the aerial parts of Stachys tetragona, a Greek endemic species

Objective: The current study was to deal the isolation and identification of secondary metabolites from Polygonum equisetiforme and evaluation of antioxidant activity of its extract.Methods: The methanol-water extract (7:3) of the air-dried aerial parts of Polygonum equisetiforme was fractionated and separated to obtain the isolated compounds by different chromatographic techniques. Structures of these compounds were elucidated by UV and 1D⁄2D H⁄ C NMR spectroscopy and compared with the literature data. The crude extract was evaluated for in vitro antioxidant activity using the 2,2 diphenyl dipicryl hydrazine (DPPH) method.Results: Ten secondary metabolites were isolated from Polygonum equisetiforme in this study. Of which three new flavonoids named as 3,5,7,2’,5’ pentahydroxyflavone 3-O-b-D-glucopyranoside (1), 3,5,7,2’,5’ pentahydroxyflavone 3-O-b-D-glucopyranoside 8 C-sulphated (2) and quercetin 3-O-β-D-glucucorinde 6''-methyl ester 8-sulphated (3) as well as quercetin 3-O-β-D-glucucorinde methyl ester (4), quercetin 3-O-β-D-glucopyranoside (5), quercetin 7-O-β-D-glucopyranoside (6), quercetin(7), myricetin (8), P-methoxy gallic acid methyl ester (9) and gallic acid (10). The antioxidant potential of P. equisetiforme extract was evaluated by investigating it's total phenolic and flavonoid content and DPPH radical scavenging activity whereby the extract showed significant antioxidant activity (IC50 = 37.45 μg/ml). The total phenolic and flavonoid content was found to be 130.79±5.502 and 45.8±1.63 μg/ml, respectively.Conclusion: Polygonum equisetiforme is a promising medicinal plant, and our study tends to support the therapeutic value of this plant as an antioxidant drug.

Download Full-text

Secondary metabolites of three endemic Centaurea L. species

Journal of the Serbian Chemical Society ◽

10.2298/jsc140318048t ◽

2014 ◽

Vol 79 (11) ◽

pp. 1355-1362 ◽

Cited By ~ 9

Author(s):

Vele Tesevic ◽

Ivana Aljancic ◽

Slobodan Milosavljevic ◽

Vlatka Vajs ◽

Iris Djordjevic ◽

...

Keyword(s):

Quantitative Analysis ◽

Nmr Spectroscopy ◽

Secondary Metabolites ◽

Sesquiterpene Lactone ◽

1H Nmr ◽

13C Nmr ◽

1H Nmr Spectroscopy ◽

13C Nmr Spectroscopy ◽

Esi Ms ◽

Aerial Parts

The aerial parts of three endemic Centaurea L. species, namely C. tomorosii Micevski, C. soskae Hayek and C. galicicae Micevski, afforded sesquiterpene lactone cnicin (1) and seven flavonoids: apigenin (2), isokaempferide (3), hispidulin (4), eupatorin (5), cirsimaritin (6), santaflavone (7) and salvigenin (8). The structures of the isolated compounds were determined by UV, 1H NMR and 13C NMR spectroscopy and HR-ESI-MS spectrometry. 1H NMR spectroscopy was used as a method for quantitative analysis of sesquiterpene lactone cnicin.

Download Full-text

Secondary Metabolites from Marrubium velutinum, Growing Wild in Greece

Zeitschrift für Naturforschung B ◽

10.1515/znb-2005-0316 ◽

2005 ◽

Vol 60 (3) ◽

pp. 328-332 ◽

Cited By ~ 7

Author(s):

Anastasia Karioti ◽

Jörg Heilmann ◽

Helen Skaltsa

Keyword(s):

Secondary Metabolites ◽

Phenylethanoid Glycosides ◽

Spectral Analyses ◽

Aerial Parts

From the aerial parts of Marrubium velutinum, two new phenylethanoid glycosides, velutinosides III-IV have been isolated together with four known phenylethanoid glycosides, as well as one new acylated flavone and five known flavonoids. The structures of the isolated compounds were established by means of NMR, MS, and UV spectral analyses

Download Full-text

Chemical composition of the essential oils from the aerial parts of two Malagasy endemic species (Apiaceae): Billburttia capensoides Sales & Hedge and Billburttia vaginoides Sales & Hedge

Natural Product Research ◽

10.1080/14786419.2018.1457669 ◽

2018 ◽

Vol 33 (8) ◽

pp. 1200-1203

Author(s):

Stephan R. Rakotonandrasana ◽

Delphin J. R. Rabehaja ◽

Mathieu Paoli ◽

Dominique de Rocca Serra ◽

Charles Andrianjara ◽

...

Keyword(s):

Chemical Composition ◽

Essential Oils ◽

Endemic Species ◽

Aerial Parts

Download Full-text

Diversity of Secondary Metabolites in Roots from Conium maculatum L.

Plants ◽

10.3390/plants9080939 ◽

2020 ◽

Vol 9 (8) ◽

pp. 939

Author(s):

Remigius Chizzola ◽

Ulrike Lohwasser

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Secondary Metabolites ◽

Bioactive Compounds ◽

High Variability ◽

Gas Chromatography Mass Spectrometry ◽

Conium Maculatum ◽

Aerial Parts ◽

Tap Root ◽

Toxic Plant

Background: Conium maculatum is known as highly toxic plant, due to piperidine alkaloids present in the aerial parts. In a first attempt, in various tap root samples, however, alkaloids could not be detected. The present study describes active compounds in the tap roots from 16 populations harvested at maturity. The compounds were extracted with dichloromethane from root pieces of single plants and analyzed by gas chromatography–mass spectrometry. Ten bioactive compounds were evaluated: five furocoumarins, two prenylated coumarins, two aliphatic C17-polyacetylenes and the phenylpropanoid elemicin. A high variability could be observed, the highest concentrations were measured for falcarindiol, xanthotoxin and isopimpinellin, the lowest for elemicin. In sum C. maculatum roots contained comparable amounts of compounds that are characteristic for Apiaceae, and also occur in vegetables as carrots, parsnip, parsley or celeriac.

Download Full-text

Secondary metabolites from the aerial parts of Sideritis germanicopolitana and their in vitro enzyme inhibitory activities

Natural Product Research ◽

10.1080/14786419.2019.1586700 ◽

2019 ◽

pp. 1-4 ◽

Cited By ~ 2

Author(s):

Hasan Kırmızıbekmez ◽

Murat Erdoğan ◽

Norbert Kúsz ◽

Nursenem Karaca ◽

Umur Erdem ◽

...

Keyword(s):

Secondary Metabolites ◽

Aerial Parts ◽

Inhibitory Activities

Download Full-text

Comparison of the Chemical Composition of Valeriana parviflora Essential Oils Collected in the Venezuelan Andes in two Different Seasons

Natural Product Communications ◽

10.1177/1934578x1501000433 ◽

2015 ◽

Vol 10 (4) ◽

pp. 1934578X1501000

Author(s):

Sammy Fernández ◽

María Rondón ◽

Janne Rojas ◽

Antonio Morales ◽

Luis Rojas-Fermin

Keyword(s):

Chemical Composition ◽

Essential Oil ◽

Essential Oils ◽

Endemic Species ◽

Rainy Season ◽

Climatic Conditions ◽

Isovaleric Acid ◽

Aerial Parts ◽

Different Seasons ◽

Main Components

The essential oils obtained by hydrodistillation of the aerial parts of Valeriana parviflora (Trevir) BM Vadillo, an endemic species of the Venezuelan Andes, collected from the same location in two different seasons (dry and rainy) of the year, were analyzed by GC/MS. The essential oil obtained during the dry season showed linalool (11.9%), eugenol (8.9%), p-menth-1-en-9-al (8.7%) and α-terpineol (7.7%) as main components, while the oil obtained from the rainy season collection showed o-xylol (16.2%), 3-methyl isovaleric acid (10.6%) and geranial (9.5%) as major compounds. Some of the differences in the composition of these oils might be due to the climatic conditions at the time of harvesting.

Download Full-text