Modern bioautography – a fast analytical tool to discover active compounds in plant extracts used for cosmetics

2017 ◽  
Author(s):  
M Oberle ◽  
J Engemann ◽  
I Klingelhöfer ◽  
G Morlock
Keyword(s):  
Plant Extracts ◽  
Analytical Tool ◽  
Active Compounds

Isolation and characterisation of biologically-active compounds from some plant extracts

1989 ◽  
Vol 25 (4) ◽  
pp. 337-342 ◽  
Author(s):  
Glenn S. Peterson ◽  
Mohamed A. Kandil ◽  
Mounir D. Abdallah ◽  
Abdel-aal A. Farag
Keyword(s):  
Plant Extracts ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds

scholarly journals Ямаан арц (Juniperus sibirica Burgsd.)-ны мутагений үйлчлэлийг дарангуйлах идэвхийн судалгаа

2017 ◽  
pp. 14-24
Author(s):  
Одонтуяа Г ◽  
Батхүү Ж
Keyword(s):  
Salmonella Typhimurium ◽  
Plant Extracts ◽  
Life Quality ◽  
Antimutagenic Activity ◽  
Isolation And Identification ◽  
Traditional Use ◽  
Cytotoxic Effects ◽  
Active Compounds ◽  
Aerial Parts ◽  
Mongolian Flora

This study evaluated the antimutagenic and cytotoxic effects of some plants growing in Mongolia and plants were selected on the basis of their traditional use in various diseases. Over the past years numbers of cancer incidences are increasing in Mongolia. There are accounted several reasons, in particular the use of less guaranteed imported food, heavy air pollution, environmental contamination and low life quality of the population. Therefore, we attempted to search antimutagenic activity among plants from the Mongolian flora and possibility of their use for preventing and treating cancer cases. The study might promote the way to fight with cancer, if we can find antimutagenic active compounds from natural crude drugs, including medicinal plants.We have examined the antimutagenic and cytotoxic effects of 20 samples, which prepared from different parts of 10 plants species. The antimutagenic and cytotoxic tests were performed as described by Ames. The bacteria used in the test are a strain of Salmonella typhimurium TA1537, and using 9-aminoacridine as direct mutagen.From the 20 plant extracts studied, extracts of Achnatherum splendens Trin. (aerial parts), Cynoglossum divaricatum Steph. (roots, stems), Juniperus sibirica Burgsd. (leaf, stem) strongly inhibited mutagenicity of 9-aminoacridine and their inhibition activity was 49.7%, 41.5%, 61.5%, 40% and 43% respectively. All plant extracts have not any cytotoxic effect on Salmonella typhimurium TA1537.From the high active plants Juniperus sibirica Burgsd. (aerial parts) which was selected for further detailed study 3 pure active compounds as JS-1, JS-2 and JS-3 were isolated. The compound JS-3 showed the high (55%) antimutagenic activity and its molecular structure was determined as cetyl alcohol or hexadecanol-1 according to its physical and chemical characteristics as well as 1H-NMR and 13C-NMR spectroscopy analysis.We have revealed that the availability of plants possessing antimutagenic activity among the Mongolian flora. Consequently, it is needed further detailed study of active plants, isolation and identification of active pure compounds, as well as possible application of the active plant products in the medicinal practice.

Modern direct bioautography for fast screening and characterization of active compounds in plant extracts used in cosmetics

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
M Oberle ◽  
P Lewits ◽  
J Engemann ◽  
I Klingelhöfer ◽  
G Morlock
Keyword(s):  
Plant Extracts ◽  
Active Compounds ◽  
Fast Screening ◽  
Direct Bioautography

scholarly journals Evaluation of Practical Applicability and Synergistic Effects of Bio-Based Food Packaging Materials Combined with Plant-Based Stabilisers

Processes ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1838
Author(s):  
Thomas Havelt ◽  
Sarah Brettschneider ◽  
Michaela Schmitz
Keyword(s):  
Plant Extracts ◽  
Food Packaging ◽  
Synergistic Effects ◽  
Aesculus Hippocastanum ◽  
Poly Lactic Acid ◽  
Thymus Vulgaris ◽  
Horse Chestnut ◽  
Active Compounds ◽  
Use Of Resources ◽  
Antioxidant Effects

Different analyses and feasibility studies have been conducted on the plant extracts of thyme (Thymus vulgaris), European horse chestnut (Aesculus hippocastanum), Nordmann fir (Abies nordmanniana), and snowdrop (Galanthus elwesii) to evaluate bio-based alternatives to common petrol-based stabilisers. For this purpose, in this study, plant extracts were incorporated into poly-lactic acid films (PLA) at different concentrations. The films’ UV absorbance and migration into packed food was analysed via photometric assays (ABTS radical cation scavenging capacity assay, β-carotene assay) and GC–MS analysis. Furthermore, the synergistic antioxidant effects of various combinations of extracts and isolated active compounds were determined. This way, antioxidant effects can be increased, allowing for a highly effective use of resources. All extracts were successfully incorporated into PLA films and showed notable photoabsorbing effects, while no migration risk was observed. Depending on extract combinations, high synergistic effects of up to 726% can be utilised to improve the effectiveness of bio-based extracts. This applies particularly to tomato paste and Aesculus hippocastanum extracts, which overall show high synergistic and antioxidant effects in combination with each other and with isolated active compounds. The study shows that it is possible to create safe bio-based antioxidant films which show even improved properties when using highlighted target combinations.

Automatised pharmacophoric deconvolution of plant extracts – application toCinchonabark crude extract

2019 ◽  
Vol 218 ◽  
pp. 441-458
Author(s):  
Laure Margueritte ◽  
Laura Duciel ◽  
Mélanie Bourjot ◽  
Catherine Vonthron-Sénécheau ◽  
Marc-André Delsuc
Keyword(s):  
Plant Extracts ◽  
Crude Extract ◽  
Raw Data ◽  
Active Compounds ◽  
On Line

We report an on-line NMR dereplication pipeline, from raw data to spectral fingerprints of the active compounds.

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