scholarly journals Distributed Biomedical Terminology Development: From Experiments to Open Process

2010 ◽  
Vol 19 (01) ◽  
pp. 58-63 ◽  
Author(s):  
C. G. Chute

Summary Objective: Can social computing efforts materially alter the distributed creation and maintenance of complex biomedical terminologies and ontologies; a review of distributed authoring history and status. Background: Social computing projects, such as Wikipedia, have dramatically altered the perception and reality of large-scale content projects and the labor required to create and maintain them. Health terminologies have become large, complex, interdependent content artifacts of increasing importance to biomedical research and the communities understanding of biology, medicine, and optimal healthcare practices. The question naturally arises as to whether social computing models and distributed authoring platforms can be applied to the voluntary, distributed authoring of high-quality terminologies and ontologies. Methods: An historical review of distributed authoring developments. Results: The trajectory of description logic-driven authoring tools, group process, and web-based platforms suggests that public distributed authoring is likely feasible and practical; however, no compelling example on the order of Wikipedia is yet extant. Nevertheless, several projects, including the Gene Ontology and the new revision of the International Classification of Disease (ICD-11) hold promise.

2018 ◽  
Author(s):  
Eric A. Kaiser ◽  
Aleksandra Igdalova ◽  
Geoffrey K. Aguirre ◽  
Brett Cucchiara

AbstractObjectiveTo identify migraineurs and headache-free individuals with an online questionnaire and automated analysis algorithm.MethodsWe created a branching-logic, web-based questionnaire—the Penn Online Evaluation of Migraine (POEM)—to obtain standardized headache history from a previously studied cohort. Responses were analyzed with an automated algorithm to assign subjects to one of several categories based on ICHD-3 (beta) criteria. Following a pre-registered protocol, this result was compared to prior diagnostic classification by a neurologist following a direct interview.ResultsOf 118 subjects contacted, 90 (76%) completed the questionnaire; of these 31 were headache-free, 29 migraine without aura (MwoA), and 30 migraine with aura (MwA). Mean age was 41 ± 6 years and 76% were female. There were no significant demographic differences between groups. The median time to complete the questionnaire was 2.5 minutes. Sensitivity of the POEM tool was 42%, 59%, and 70%, and specificity was 100%, 84%, and 94% for headache-free, MwoA, and MwA, respectively. Sensitivity and specificity of the POEM tool for migraine overall (with or without aura), was 83% and 90%, respectively.ConclusionsThe POEM web-based questionnaire, and associated analysis routines, identifies headache-free and migraine subjects with good specificity. It may be useful for classifying subjects for large-scale research studies.Trial Registration:https://osf.io/sq9ef


2020 ◽  
pp. injuryprev-2019-043464
Author(s):  
Linda Quan ◽  
Brianna Mills ◽  
Suet Sen Chau ◽  
Elizabeth Bennett ◽  
Kaylin Bolt ◽  
...  

BackgroundAlthough most persons over 5 years of age drown in open water, few laws have sought to regulate open water swim sites. We examined the association between regulations for designated open water swim sites and open water drowning death rates by state.MethodsUsing International Classification of Disease (ICD)-10 codes in the CDC Web-based Injury Statistics Query and Reporting System (WISQARS), we identified and calculated open water drowning deaths involving all ages from 2012 to 2017 for 50 states and calculated open water drowning death rates. We then identified and categorised types of state regulations (lifeguards, water quality, rescue equipment, tracking/planning/reporting and signage) for open water swim sites in place in 2017 for a sample of 30 states (20 high-drowning, 10 low-drowning). Analyses evaluated associations between open water drowning rates in three groups (overall, youth and non-white) and the total number and types of state regulations.ResultsSwim site regulations and open water drowning death rates for 10 839 victims were associated in all regression models. States with more types of regulations had lower open water drowning death rates in a dose-response relationship. States lacking regulations compared with states with all five types of regulations had open water drowning death rates 3.02 times higher among youth (95% CI 1.82 to 4.99) and 4.16 times higher among non-white residents (95% CI 2.46 to 7.05). Lifeguard and tracking/planning/reporting regulations were associated with a 33% and 45% reduction in open water drowning rates overall and among those aged 0–17 years.ConclusionStates’ open water swim area regulations, especially addressing tracking/planning/reporting and lifeguards, were associated with lower open water drowning death rates.


2018 ◽  
Author(s):  
Michael N. Edmonson ◽  
Aman N. Patel ◽  
Dale J. Hedges ◽  
Zhaoming Wang ◽  
Evadnie Rampersaud ◽  
...  

AbstractVariant interpretation in the era of next-generation sequencing (NGS) is challenging. While many resources and guidelines are available to assist with this task, few integrated end-to-end tools exist. Here we present “PeCanPIE” – the Pediatric Cancer Variant Pathogenicity Information Exchange, a web- and cloud-based platform for annotation, identification, and classification of variations in known or putative disease genes. Starting from a set of variants in Variant Call Format (VCF), variants are annotated, ranked by putative pathogenicity, and presented for formal classification using a decision-support interface based on published guidelines from the American College of Medical Genetics and Genomics (ACMG). The system can accept files containing millions of variants and handle single-nucleotide variants (SNVs), simple insertions/deletions (indels), multiple-nucleotide variants (MNVs), and complex substitutions. PeCanPIE has been applied to classify variant pathogenicity in cancer predisposition genes in two large-scale investigations involving >4,000 pediatric cancer patients, and serves as a repository for the expert-reviewed results. While PeCanPIE’s web-based interface was designed to be accessible to non-bioinformaticians, its back end pipelines may also be run independently on the cloud, facilitating direct integration and broader adoption. PeCanPIE is publicly available and free for research use.


2013 ◽  
Author(s):  
Laura S. Hamilton ◽  
Stephen P. Klein ◽  
William Lorie

2020 ◽  
Vol 59 (04) ◽  
pp. 294-299 ◽  
Author(s):  
Lutz S. Freudenberg ◽  
Ulf Dittmer ◽  
Ken Herrmann

Abstract Introduction Preparations of health systems to accommodate large number of severely ill COVID-19 patients in March/April 2020 has a significant impact on nuclear medicine departments. Materials and Methods A web-based questionnaire was designed to differentiate the impact of the pandemic on inpatient and outpatient nuclear medicine operations and on public versus private health systems, respectively. Questions were addressing the following issues: impact on nuclear medicine diagnostics and therapy, use of recommendations, personal protective equipment, and organizational adaptations. The survey was available for 6 days and closed on April 20, 2020. Results 113 complete responses were recorded. Nearly all participants (97 %) report a decline of nuclear medicine diagnostic procedures. The mean reduction in the last three weeks for PET/CT, scintigraphies of bone, myocardium, lung thyroid, sentinel lymph-node are –14.4 %, –47.2 %, –47.5 %, –40.7 %, –58.4 %, and –25.2 % respectively. Furthermore, 76 % of the participants report a reduction in therapies especially for benign thyroid disease (-41.8 %) and radiosynoviorthesis (–53.8 %) while tumor therapies remained mainly stable. 48 % of the participants report a shortage of personal protective equipment. Conclusions Nuclear medicine services are notably reduced 3 weeks after the SARS-CoV-2 pandemic reached Germany, Austria and Switzerland on a large scale. We must be aware that the current crisis will also have a significant economic impact on the healthcare system. As the survey cannot adapt to daily dynamic changes in priorities, it serves as a first snapshot requiring follow-up studies and comparisons with other countries and regions.


2009 ◽  
pp. 27-53
Author(s):  
A. Yu. Kudryavtsev

Diversity of plant communities in the nature reserve “Privolzhskaya Forest-Steppe”, Ostrovtsovsky area, is analyzed on the basis of the large-scale vegetation mapping data from 2000. The plant community classi­fication based on the Russian ecologic-phytocoenotic approach is carried out. 12 plant formations and 21 associations are distinguished according to dominant species and a combination of ecologic-phytocoenotic groups of species. A list of vegetation classification units as well as the characteristics of theshrub and woody communities are given in this paper.


1996 ◽  
pp. 64-67 ◽  
Author(s):  
Nguen Nghia Thin ◽  
Nguen Ba Thu ◽  
Tran Van Thuy

The tropical seasonal rainy evergreen broad-leaved forest vegetation of the Cucphoung National Park has been classified and the distribution of plant communities has been shown on the map using the relations of vegetation to geology, geomorphology and pedology. The method of vegetation mapping includes: 1) the identifying of vegetation types in the remote-sensed materials (aerial photographs and satellite images); 2) field work to compile the interpretation keys and to characterize all the communities of a study area; 3) compilation of the final vegetation map using the combined information. In the classification presented a number of different level vegetation units have been identified: formation classes (3), formation sub-classes (3), formation groups (3), formations (4), subformations (10) and communities (19). Communities have been taken as mapping units. So in the vegetation map of the National Park 19 vegetation categories has been shown altogether, among them 13 are natural primary communities, and 6 are the secondary, anthropogenic ones. The secondary succession goes through 3 main stages: grassland herbaceous xerophytic vegetation, xerophytic scrub, dense forest.


2020 ◽  
Author(s):  
Thomas Gaisl ◽  
Naser Musli ◽  
Patrick Baumgartner ◽  
Marc Meier ◽  
Silvana K Rampini ◽  
...  

BACKGROUND The health aspects, disease frequencies, and specific health interests of prisoners and refugees are poorly understood. Importantly, access to the health care system is limited for this vulnerable population. There has been no systematic investigation to understand the health issues of inmates in Switzerland. Furthermore, little is known on how recent migration flows in Europe may have affected the health conditions of inmates. OBJECTIVE The Swiss Prison Study (SWIPS) is a large-scale observational study with the aim of establishing a public health registry in northern-central Switzerland. The primary objective is to establish a central database to assess disease prevalence (ie, International Classification of Diseases-10 codes [German modification]) among prisoners. The secondary objectives include the following: (1) to compare the 2015 versus 2020 disease prevalence among inmates against a representative sample from the local resident population, (2) to assess longitudinal changes in disease prevalence from 2015 to 2020 by using cross-sectional medical records from all inmates at the Police Prison Zurich, Switzerland, and (3) to identify unrecognized health problems to prepare successful public health strategies. METHODS Demographic and health-related data such as age, sex, country of origin, duration of imprisonment, medication (including the drug name, brand, dosage, and release), and medical history (including the International Classification of Diseases-10 codes [German modification] for all diagnoses and external results that are part of the medical history in the prison) have been deposited in a central register over a span of 5 years (January 2015 to August 2020). The final cohort is expected to comprise approximately 50,000 to 60,000 prisoners from the Police Prison Zurich, Switzerland. RESULTS This study was approved on August 5, 2019 by the ethical committee of the Canton of Zurich with the registration code KEK-ZH No. 2019-01055 and funded in August 2020 by the “Walter and Gertrud Siegenthaler” foundation and the “Theodor and Ida Herzog-Egli” foundation. This study is registered with the International Standard Randomized Controlled Trial Number registry. Data collection started in August 2019 and results are expected to be published in 2021. Findings will be disseminated through scientific papers as well as presentations and public events. CONCLUSIONS This study will construct a valuable database of information regarding the health of inmates and refugees in Swiss prisons and will act as groundwork for future interventions in this vulnerable population. CLINICALTRIAL ISRCTN registry ISRCTN11714665; http://www.isrctn.com/ISRCTN11714665 INTERNATIONAL REGISTERED REPORT DERR1-10.2196/23973


Author(s):  
Marc N. Potenza ◽  
Kyle A. Faust ◽  
David Faust

As digital technology development continues to expand, both its positive and negative applications have also grown. As such, it is essential to continue gathering data on the many types of digital technologies, their overall effects, and their impact on public health. The World Health Organization’s inclusion of Gaming Disorder in the eleventh edition of the International Classification of Disease (ICD-11) indicates that some of the problematic effects of gaming are similar to those of substance-use disorders and gambling. Certain behaviors easily engaged in via the internet may also lead to compulsive levels of use in certain users, such as shopping or pornography use. In contrast, digital technologies can also lead to improvements in and wider accessibility to mental health treatments. Furthermore, various types of digital technologies can also lead to benefits such as increased productivity or social functioning. By more effectively understanding the impacts of all types of digital technologies, we can aim to maximize their benefits while minimizing or preventing their negative impacts.


Author(s):  
Mathieu Turgeon-Pelchat ◽  
Samuel Foucher ◽  
Yacine Bouroubi

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