scholarly journals Global Burden of Stroke

2018 ◽  
Vol 38 (02) ◽  
pp. 208-211 ◽  
Author(s):  
Mira Katan ◽  
Andreas Luft
Keyword(s):  
Hemorrhagic Stroke ◽  
Middle Income ◽  
Stroke Incidence ◽  
Middle Income Countries ◽  
The Past ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Incidence And Mortality ◽  
Geographical Regions ◽  
Life Years Lost

AbstractStroke is the second leading cause of death and a major cause of disability worldwide. Its incidence is increasing because the population ages. In addition, more young people are affected by stroke in low- and middle-income countries. Ischemic stroke is more frequent but hemorrhagic stroke is responsible for more deaths and disability-adjusted life-years lost. Incidence and mortality of stroke differ between countries, geographical regions, and ethnic groups. In high-income countries mainly, improvements in prevention, acute treatment, and neurorehabilitation have led to a substantial decrease in the burden of stroke over the past 30 years. This article reviews the epidemiological and clinical data concerning stroke incidence and burden around the globe.

World Stroke Organization (WSO): Global Stroke Fact Sheet 2022

2022 ◽  
Vol 17 (1) ◽  
pp. 18-29 ◽  
Author(s):  
Valery L Feigin ◽  
Michael Brainin ◽  
Bo Norrving ◽  
Sheila Martins ◽  
Ralph L Sacco ◽  
...  
Keyword(s):  
Cause Of Death ◽  
Absolute Number ◽  
Middle Income ◽  
Fact Sheet ◽  
Middle Income Countries ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Global Cost ◽  
External Stakeholders ◽  
Life Years Lost

Stroke remains the second-leading cause of death and the third-leading cause of death and disability combined (as expressed by disability-adjusted life-years lost – DALYs) in the world. The estimated global cost of stroke is over US$721 billion (0.66% of the global GDP). From 1990 to 2019, the burden (in terms of the absolute number of cases) increased substantially (70.0% increase in incident strokes, 43.0% deaths from stroke, 102.0% prevalent strokes, and 143.0% DALYs), with the bulk of the global stroke burden (86.0% of deaths and 89.0% of DALYs) residing in lower-income and lower-middle-income countries (LMIC). This World Stroke Organisation (WSO) Global Stroke Fact Sheet 2022 provides the most updated information that can be used to inform communication with all internal and external stakeholders; all statistics have been reviewed and approved for use by the WSO Executive Committee as well as leaders from the Global Burden of Disease research group.

Injury prevention and control

2021 ◽  
pp. 361-376
Author(s):  
Corinne Peek-Asa ◽  
Adnan A. Hyder
Keyword(s):  
Injury Prevention ◽  
Low Income ◽  
Prevention And Control ◽  
Low Income Countries ◽  
Middle Income ◽  
Injury Rates ◽  
Middle Income Countries ◽  
Disability Adjusted Life ◽  
Life Years ◽  
And Control

Injuries are among the leading causes of death and disability throughout the world and contribute disproportionately to premature life lost. Injury rates are highest among middle- and low-income countries. According to analyses of the 2016 Global Burden of Disease data, injuries cause over 4.6 million deaths per year, accounting for nearly 8.4% of all deaths and 10.7% of disability-adjusted life years. Many opportunities to implement injury prevention strategies exist, and a systematic approach to injury prevention can help identify the most effective and efficient approaches. Building capacity for injury prevention activities in low- and middle-income countries is an important public health priority.

scholarly journals Global Disparities Between Pediatric Publications and Disease Burden From 2006 to 2015

2019 ◽  
Vol 6 ◽  
pp. 2333794X1983129 ◽  
Author(s):  
Elizabeth M. Keating ◽  
Heather Haq ◽  
Chris A. Rees ◽  
Kirk A. Dearden ◽  
Samuel A. Luboga ◽  
...  
Keyword(s):  
Burden Of Disease ◽  
Disease Burden ◽  
Rank Order ◽  
Original Research ◽  
Middle Income ◽  
Childhood Disease ◽  
Middle Income Countries ◽  
Funding Sources ◽  
Disability Adjusted Life ◽  
Life Years

There is a disproportionate burden of pediatric disease in low- and middle-income countries (LMICs); however, the proportion and relation of published articles to childhood disease burden in LMICs have not been assessed previously. This study aimed to determine whether published articles and disease topics from research conducted in LMICs in the most widely cited pediatric journals reflected the global burden of childhood disease. We reviewed all articles published from 2006 to 2015 in the 3 pediatric journals with the highest Eigenfactor scores to identify studies conducted in the World Bank–designated LMICs. We abstracted study topic, design, purpose, country, and funding sources. We derived descriptive statistics, Fisher’s exact χ2 test, Monte Carlo estimates, and Spearman’s rank order coefficients. Of the 19 676 articles reviewed, 10 494 were original research articles. Of those, 965 (9.2%) were conducted in LMICs. Over the study period, the proportion of published articles originating from LMICs increased ( r2 = 0.77). Disease topics did not reflect the underlying burden of disease as measured in disability-adjusted life years (Spearman’s rank order coefficient = 0.25). Despite bearing the majority of the world’s burden of disease, articles from LMICs made up a small proportion of all published articles in the 3 pediatric journals with the highest Eigenfactor scores. The number of published articles from LMICs increased over the study period; nevertheless, the topics did not coincide with the burden of disease in LMICs. These discrepancies highlight the need for development of a research agenda to address the diseases that are the greatest threat to the majority of children worldwide.

scholarly journals Atlas of the Global Burden of Stroke (1990-2013): The GBD 2013 Study

2015 ◽  
Vol 45 (3) ◽  
pp. 230-236 ◽  
Author(s):  
Valery L. Feigin ◽  
George A. Mensah ◽  
Bo Norrving ◽  
Christopher J.L. Murray ◽  
Gregory A. Roth ◽  
...  
Keyword(s):  
Case Fatality ◽  
Absolute Number ◽  
Global Burden ◽  
Middle Income ◽  
Stroke Incidence ◽  
Disability Adjusted Life ◽  
Life Years ◽  
The World ◽  
Growth And Aging ◽  
Incidence Prevalence

Background: World mapping is an important tool to visualize stroke burden and its trends in various regions and countries. Objectives: To show geographic patterns of incidence, prevalence, mortality, disability-adjusted life years (DALYs) and years lived with disability (YLDs) and their trends for ischemic stroke and hemorrhagic stroke in the world for 1990-2013. Methodology: Stroke incidence, prevalence, mortality, DALYs and YLDs were estimated following the general approach of the Global Burden of Disease (GBD) 2010 with several important improvements in methods. Data were updated for mortality (through April 2014) and stroke incidence, prevalence, case fatality and severity through 2013. Death was estimated using an ensemble modeling approach. A new software package, DisMod-MR 2.0, was used as part of a custom modeling process to estimate YLDs. All rates were age-standardized to new GBD estimates of global population. All estimates have been computed with 95% uncertainty intervals. Results: Age-standardized incidence, mortality, prevalence and DALYs/YLDs declined over the period from 1990 to 2013. However, the absolute number of people affected by stroke has substantially increased across all countries in the world over the same time period, suggesting that the global stroke burden continues to increase. There were significant geographical (country and regional) differences in stroke burden in the world, with the majority of the burden borne by low- and middle-income countries. Conclusions: Global burden of stroke has continued to increase in spite of dramatic declines in age-standardized incidence, prevalence, mortality rates and disability. Population growth and aging have played an important role in the observed increase in stroke burden.

Global evidence generation

2020 ◽  
pp. 453-464
Author(s):  
Adesola Ogunniyi
Keyword(s):  
Depressive Disorders ◽  
World Health ◽  
Middle Income ◽  
Middle Income Countries ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Special Mention ◽  
Global Burden Of Diseases ◽  
Health Organization ◽  
Evidence Generation

Disparities in the distribution of neurological and mental health disorders (NMHD) in different regions of the world can provide clues on the putative risk factors while providing basis for intervention strategies. This chapter utilizes the Global Burden of Diseases (GBD) data and the disability adjusted life years (DALY) calculations in the different World Health Organization (WHO) regions to adduce reasons for the peculiarities observed. The focus is on the most common NMHD, particularly those for which preventive strategies are likely to result in improved health outcomes for the majority of those affected. In this regard, stroke, epilepsy, and depressive disorders have been given special attention because of their high societal impact and the extensive studies from different regions. Dementia deserves special mention in view of its looming epidemic in low and middle income countries (LMICs), while its burden is lessening in high income countries (HICs) due to appropriate interventions and higher education.

The epidemiology and pathophysiology of coronary artery disease

2010 ◽  
pp. 2-17
Author(s):  
Robert A. Henderson ◽  
Leong Lee
Keyword(s):  
Premature Death ◽  
Western World ◽  
Middle Income ◽  
Middle Income Countries ◽  
Obesity And Diabetes ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Rising Incidence ◽  
Artery Disease

Advances in the prevention and treatment of coronary heart disease (CHD) have led to significant improvements in prognosis and quality of life, but globally CHD remains a leading cause of premature death and disability. In 2001 CHD was responsible for 11.8% of all deaths in low- and middle-income countries and 17.3% in high-income countries, accounting for over 7 million deaths worldwide. By 2020 CHD is projected to be the leading cause of death and disability-adjusted life years, reflecting a rapidly increasing prevalence in developing countries and Eastern Europe, and the rising incidence of obesity and diabetes in the Western world.

scholarly journals Emergency care surveillance and emergency care registries in low-income and middle-income countries: conceptual challenges and future directions for research

2019 ◽  
Vol 4 (Suppl 6) ◽  
pp. e001442 ◽  
Author(s):  
Hani Mowafi ◽  
Christine Ngaruiya ◽  
Gerard O'Reilly ◽  
Olive Kobusingye ◽  
Vikas Kapil ◽  
...  
Keyword(s):  
Data Collection ◽  
Emergency Care ◽  
Low Income ◽  
Working Group ◽  
Policy Making ◽  
Population Based ◽  
Middle Income ◽  
Middle Income Countries ◽  
Disability Adjusted Life ◽  
Life Years

Despite the fact that the 15 leading causes of global deaths and disability-adjusted life years are from conditions amenable to emergency care, and that this burden is highest in low-income and middle-income countries (LMICs), there is a paucity of research on LMIC emergency care to guide policy making, resource allocation and service provision. A literature review of the 550 articles on LMIC emergency care published in the 10-year period from 2007 to 2016 yielded 106 articles for LMIC emergency care surveillance and registry research. Few articles were from established longitudinal surveillance or registries and primarily composed of short-term data collection. Using these articles, a working group was convened by the US National Institutes of Health Fogarty International Center to discuss challenges and potential solutions for established systems to better understand global emergency care in LMICs. The working group focused on potential uses for emergency care surveillance and registry data to improve the quality of services provided to patients. Challenges included a lack of dedicated resources for such research in LMIC settings as well as over-reliance on facility-based data collection without known correlation to the overall burden of emergency conditions in the broader community. The group outlined potential solutions including incorporating data from sources beyond traditional health records, use of standard clinical forms that embed data needed for research and policy making and structured population-based research to establish clear linkages between what is seen in emergency units and the wider community. The group then identified current gaps in LMIC emergency care surveillance and registry research to form a research agenda for the future.

scholarly journals Burden of Stroke in Myanmar

2021 ◽  
pp. 49-51
Author(s):  
Narayanaswamy Venketasubramanian ◽  
Yee Mon Khine ◽  
Ohnmar Ohnmar ◽  
Myat Po Po Kyaw Khin ◽  
Min Thit Win
Keyword(s):  
Rural Areas ◽  
Mechanical Thrombectomy ◽  
Disability Adjusted Life Years ◽  
Stroke Units ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Lower Blood ◽  
Life Years Lost ◽  
Standardized Mortality Rate ◽  
Age And Sex

Myanmar is home to over 51 million people. The age- and sex-standardized mortality rate due to stroke is 165.4/100,000, while the rate of age- and sex-standardized disability-adjusted life years lost due to stroke is 2971.3/100,000. The prevalence of stroke among adults aged 40–99 years is 1.5%. Stroke is the leading cause of morbidity and mortality and comprises 20% of the neurological workload. There are only 10 stroke units in the whole country. Doctors are aware of the importance of hypertension in stroke prevention and the need for physiotherapy after stroke, but, until recently and in rural areas, they also tend to use steroids and neuroprotectants, and lower blood pressure aggressively acutely after stroke; antiplatelets are not widely used. Thrombolysis service is available at some tertiary centers but mechanical thrombectomy is not yet available.

scholarly journals Obesities: A New Peer-Reviewed Open-Access Interdisciplinary Journal Fostering Research on Multifactorial Obesity and Associated Cardiometabolic Disorders

Obesities ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 26-28
Author(s):  
Bruno Guigas
Keyword(s):  
Open Access ◽  
Industrialized Countries ◽  
Obesity Prevalence ◽  
Middle Income ◽  
Middle Income Countries ◽  
The Past ◽  
Urban Transition ◽  
Cardiometabolic Disorders ◽  
Interdisciplinary Journal ◽  
Low And Middle Income

Obesity prevalence has increased continuously over the past 50 years, a dramatic worldwide expansion not only limited to industrialized countries but also observed in a large number of low- and middle-income countries experiencing rapid rural–urban transition [...]

scholarly journals Tobacco Control in Low- and Middle-Income Countries: Changing the Present to Help the Future

2018 ◽  
Vol 13 (4) ◽  
pp. 187-188 ◽  
Author(s):  
Bethany Hipple Walters ◽  
Ionela Petrea ◽  
Harry Lando
Keyword(s):  
World Health Organization ◽  
World Health ◽  
Second Hand Smoke ◽  
Vulnerable Children ◽  
Middle Income ◽  
Middle Income Countries ◽  
The Past ◽  
Second Hand Smoke Exposure ◽  
Health Organization ◽  
Low And Middle Income

While the global smoking rate has dropped in the past 30 years (from 41.2% of men in 1980 to 31.1% in 2012 and from 10.6% of women in 1980 to 6.2% in 2012), the number of tobacco smokers has increased due to population growth (Ng et al., 2014). This tobacco use and second-hand smoke exposure continue to harm people worldwide. Those harmed are often vulnerable: children, those living in low- and middle-income countries (LMICs), those with existing diseases, etc. As noted by the World Health Organization (WHO), nearly 80% of those who smoke live in a LMIC (World Health Organization, 2017). Furthermore, it is often those who are more socio-economically disadvantaged or less educated in LMICs that are exposed to second-hand smoke at home and work (Nazar, Lee, Arora, & Millett, 2015).

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