Medial Plication Using an Arthroscopic All-Inside Technique for Treatment of Patellar Instability in Adolescents

2021 ◽  
Author(s):  
Gang Ji ◽  
Jianwei Zhou ◽  
Jinbao Gao ◽  
Weixia Bai ◽  
Fei Wang
Keyword(s):  
Computed Tomography ◽  
Patellar Dislocation ◽  
Patellar Instability ◽  
Computed Tomography Scan ◽  
Cosmetic Results ◽  
Good Cosmetic ◽  
Physical Examinations ◽  
Medial Plication ◽  
Tomography Scan

AbstractThe purpose of this study was to present a medial plication using an arthroscopic all-inside technique for the treatment of patellar instability in adolescents. From July 2009 to June 2012, 19 patients with acute patellar dislocation were operated by this technique. Of these patients, follow-up was available in 17 patients at an average of 3 years (range: 1.5–4 years). At the follow-up, we evaluated the patients with physical examinations, radiographs, computed tomography scan, as well as the Lysholm and Kujala scoring scales. No recurrence of patellar instability has been found. The recovery of knee mobilization resulted to be good. We think this could be a valid technique to treat patellar instability in adolescents with less associated morbidity and good cosmetic results.

Adaptive Dosing of Nivolumab + Ipilimumab Immunotherapy Based Upon Early, Interim Radiographic Assessment in Advanced Melanoma (The ADAPT-IT Study)

2021 ◽  
Author(s):  
Michael A. Postow ◽  
Debra A. Goldman ◽  
Alexander N. Shoushtari ◽  
Allison Betof Warner ◽  
Margaret K. Callahan ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Progression Free Survival ◽  
Advanced Melanoma ◽  
Computed Tomography Scan ◽  
Free Survival ◽  
Immunotherapy Trial ◽  
Grade 3 ◽  
Almost All ◽  
Tomography Scan

PURPOSE Nivolumab + ipilimumab (nivo + ipi) is highly efficacious but has high toxicity. Standard treatment in advanced melanoma is four doses of nivo + ipi followed by nivo alone. Whether four doses of nivo + ipi are needed is unclear. METHODS The Adaptively Dosed ImmunoTherapy Trial (ADAPT-IT) study ( NCT03122522 ) is a multicenter, single-arm phase II clinical trial. Patients received two doses of nivo (1 mg/kg) + ipi (3 mg/kg) followed by a computed tomography scan at week 6. Patients without new lesions or index lesion tumor growth of > 4% had protocol-defined early favorable antitumor effect (FATE) and ceased nivo + ipi, transitioning to nivo monotherapy. Patients without FATE at week 6 received the standard third and fourth doses of nivo + ipi followed by nivo monotherapy. The primary end point was response rate by RECIST 1.1 at week 12. Secondary end points included additional efficacy assessments and safety. RESULTS Sixty patients were enrolled; 41 patients (68%) had FATE at week 6 and met criteria for stopping nivo + ipi. Best overall response rates by RECIST at week 12 or any time afterward were 48% (95% CI, 35 to 62) and 58% (95% CI, 45 to 71), respectively. With a median follow-up of 25 months, the estimated 18-month progression-free survival and overall survival are 52% and 80%, respectively. Fifty seven percent of patients had grade 3-5 treatment-related toxicity. CONCLUSION The efficacy and toxicity of standard four dose nivo + ipi induction therapy in melanoma is likely driven by the first two doses. An interim computed tomography scan after two doses guided cessation of combination dosing and identified almost all responders. Longer follow-up and further study are needed to fully understand the implications of a shortened induction course of nivo + ipi.

scholarly journals Voluminous Intrapericardial Lipoma Mimicking Pericardial Effusion

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Fabíola Prado de Morais ◽  
Noah Romero Nakajima ◽  
Olívia Félix Marconi Andalécio ◽  
Pedro de Santana Prudente ◽  
Guilherme Emílio Ferreira ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pericardial Effusion ◽  
Signs And Symptoms ◽  
Tumor Location ◽  
Pathological Examination ◽  
Computed Tomography Scan ◽  
Radiologic Imaging ◽  
Heart Tumors ◽  
Tomography Scan

Lipomas are rare primary heart tumors and may involve the endocardium, myocardium, or pericardium. Signs and symptoms depend on the tumor location and size. The intrapericardial lipoma we report has massive dimensions and mimics a pericardial effusion. A 38-year-old male complained of dyspnea and precordial pain. On physical examination, heart sounds were diminished. The patient had received extensive medication for a clinically suspected pericardial effusion due to heart failure. A voluminous mass resembling fat within the pericardial sac was revealed by transesophageal echocardiography and a computed tomography scan. The tumor was removed successfully by a subxiphoid surgical approach. The diagnosis of a 635 gram intrapericardial lipoma was confirmed by pathological examination. After surgery, the patient recovered well and was completely asymptomatic at a follow-up at 90 days. No medications were being taken since. The diagnosis of a pericardial effusion should be secured by imaging exams to avoid unnecessary medications. Cardiac lipomas can be readily recognized by their typical features on radiologic imaging. The surgical pathology examination confirms the diagnosis and rules out malignancy criteria.

scholarly journals Metachronous Bilateral Isolated Adrenal Metastasis from Rectal Adenocarcinoma: A Case Report

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
H. Jabir ◽  
N. Tawfiq ◽  
M. Moukhlissi ◽  
M. Akssim ◽  
A. Guensi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Computed Tomography ◽  
Rectal Cancer ◽  
Histopathological Examination ◽  
Rectal Adenocarcinoma ◽  
Adrenal Metastasis ◽  
Computed Tomography Scan ◽  
Serum Carcinoembryonic Antigen ◽  
Tomography Scan

We report a case of adrenal metastasis from colorectal cancer in a 54-year-old woman. Nine months after resection for advanced rectal carcinoma, a computed tomography scan revealed bilateral adrenal metastasis. The level of serum carcinoembryonic antigen was normal. A bilateral adrenalectomy was performed after chemotherapy. Histopathological examination showed adenocarcinoma, compatible with metastasis from the rectal cancer. Adrenal metastasis should be considered in the patients’ follow-up for colorectal cancer.

Role of routine computed tomography scan in the oncological follow up of patients treated by radical cystectomy for bladder cancer

2016 ◽  
Vol 23 (10) ◽  
pp. 840-846 ◽  
Author(s):  
Quentin Alimi ◽  
Grégory Verhoest ◽  
Solene-Florence Kammerer-Jacquet ◽  
Romain Mathieu ◽  
Nathalie Rioux-Leclercq ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Computed Tomography Scan ◽  
Tomography Scan

Is surveillance without immediate treatment an option for newly diagnosed testicular germ-cell cancer patients with borderline size retroperitoneal lymph nodes on computed tomography scan?

2018 ◽  
Vol 36 (6_suppl) ◽  
pp. 560-560
Author(s):  
Nadav Milk ◽  
Ilan Leibovitch ◽  
Daniel Keizman ◽  
Hadas Dresler ◽  
Itay Sternberg
Keyword(s):  
Computed Tomography ◽  
Lymph Nodes ◽  
Clinical Laboratory ◽  
Cell Cancer ◽  
Tumor Board ◽  
Tumor Type ◽  
Computed Tomography Scan ◽  
Tomography Scan ◽  
Undetermined Significance

560 Background: The AJCC TNM Staging System for Testicular Cancer (TC) does not set a minimal diameter to define positive lymph nodes (LN) on computed tomography scan. It is common to refer to LN ≥ 1 cm in diameter as positive, even though benign LN in the borderline size of 1-1.5cm are common. Our goal is to describe the outcome of TC patients with borderline size retroperitoneal LN of undetermined significance managed initially with surveillance. Methods: We retrospectively reviewed the medical records of all TC patients treated at our institution during 2006-2016. Demographic, clinical, laboratory, imaging, pathological, treatment and surveillance data were obtained. Results: Of a total of 109 TC patients, 25 patients (22.7%) with borderline size LN were assigned to an active surveillance protocol by our tumor board. Median age at the time of orchiectomy was 37.2 years (IQR, 23.9-40.3). With a median follow-up of 3.9 years (IQR 1.7-6.5), overall survival rate in the group was 100%. Nine of 25 patients (36%) relapsed and were treated within a median of 4.9 months (IQR 2.2-5.5). Median follow-up for 16 patients who did not relapse was 3.4 years (IQR 1.5-5.4). Relapse-free survival was 71% (95% CI 48-85), and 61% (95% CI 38-77) at one and two years, respectively. Orchiectomy pathology included pure seminoma in 18/25 (72%), and a nonseminomatous tumor in 7/25 (28%). Tumor type was not associated with likelihood of relapse (p = 0.66). The median LN diameter at the time of diagnosis was 11 mm (IQR 9-12, mean 10.4). LN diameter was not associated with likelihood of relapse (p = 0.34). Patients who relapsed during follow-up were significantly younger at the time of TC diagnosis than patients who did not relapse (Median age 23.9 years [IQR 19.6-35.2] and 39.2 years [IQR 34.3-47.9] respectively, p = 0.0056). Conclusions: Surveillance alone for TC patients with borderline size LN of undetermined significance at diagnosis is a possible option and may help avoid overtreatment in 60% of these patients.

Response to Re: Role of routine computed tomography scan in the oncological follow up of patients treated by radical cystectomy for bladder cancer

2017 ◽  
Vol 24 (3) ◽  
pp. 242-243 ◽  
Author(s):  
Quentin Alimi ◽  
Grégory Verhoest ◽  
Solene-Florence Kammerer-Jacquet ◽  
Romain Mathieu ◽  
Karim Bensalah ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Computed Tomography Scan ◽  
Tomography Scan

scholarly journals Unusual Recto-colonic Tubular Duplication in a Female Neonate

2019 ◽  
Vol 8 (1) ◽  
pp. 5
Author(s):  
Kechiche Nahla ◽  
Rabeb Farhani ◽  
Rachida Lamiri ◽  
Mongi Mekki ◽  
Mohssen Belguith ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Barium Enema ◽  
Unusual Case ◽  
Computed Tomography Scan ◽  
Double Contrast ◽  
Colonic Duplication ◽  
Rectovestibular Fistula ◽  
The Common ◽  
Tomography Scan

Complete tubular colonic duplication is exceedingly rare. A second ectopic opening in the perineum other than a normally cited anus could be an unusual presentation. We report an unusual case of recto-colonic duplication in a 16-day-old girl who presented with fecal discharge from a vestibular opening in addition to a normally situated anus. The diagnosis of total recto-colonic tubular duplication associated with a rectovestibular fistula and a normal anus was confirmed by barium enema and computed tomography scan with double contrast. At operation, we performed a long transanal incision of the common septum to create an anastomosis between the normal and duplicated colon with complete submucosal excision of the rectovestibular fistula. The patient was doing well at 3-year follow-up examination.

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