Why and How Stories Matter in Treating Children with T1DM—Best Practice from CDiC

AbstractType 1 diabetes mellitus (T1DM) is a lifelong disorder that mostly happens any time during childhood. It needs constant care and attention. Self-management becomes very essential as there are multiple factors that influence management of blood glucose levels and good outcomes. Diabetes education1 is essential for this and it involves the process of providing the person with the knowledge and skills needed to perform diabetes self-care, manage crises, and to make lifestyle changes to successfully manage their life. It begins with teaching of survival skills and continues with higher learning to fit diabetes into lives of people with diabetes rather than changing the lives to manage diabetes. Although parents are responsible for this initially, children must be part of this learning and journey as they are the one who must deal with diabetes in their life.Although knowledge transfer from scientific (truth and fact based) and narrative story (experience and meaning based) is fundamentally different but narrative or stories are better absorbed and retained. Storytelling and experience sharing are rapidly developing fields in medical education, but its potential has yet to be realized in medical education. The Changing Diabetes in Children program focused at reaching out to the economically underprivileged children with T1DM has implemented the use of stories to help the T1DM child learn to take insulin injections and understand the basic do’s and don’t’s for proper diabetes management and motivate them to become self-reliant and independent adults in long run.

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Modern technologies in diabetes management - continuous glucose monitoring and insulin pump therapy

Public health of the Far East Peer-reviewed scientific and practical journal ◽

10.33454/1728-1261-2021-1-50-55 ◽

2021 ◽

Vol 87 (1) ◽

pp. 50-55

Author(s):

E.Yu. Pyankova ◽

◽

L.A. Anshakova ◽

I.A. Pyankov ◽

S.V. Yegorova ◽

...

Keyword(s):

Blood Glucose ◽

Diabetes Management ◽

Insulin Pump ◽

Glucose Monitoring ◽

Insulin Pump Therapy ◽

Pump Therapy ◽

Glucose Levels ◽

Blood Glucose Levels ◽

The Individual ◽

Glucose Lowering Therapy

The problems of complications of diabetes mellitus cannot be solved without constant monitoring of blood glucose levels. The evolution of additional technologies for the determination of glucose in the blood of the last decades makes it possible to more accurately predict the risks of complications, both in the individual and in the patient population as a whole. The article provides an overview of the methods used in modern diabetology, facilitating control over the variability of blood glucose levels and helping in a more accurate selection of glucose-lowering therapy. All presented methods are currently working in real clinical practice in the Khabarovsk Krai

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Optimizing Macronutrients in People with Diabetes

Journal of Social Health and Diabetes ◽

10.1055/s-0038-1675684 ◽

2018 ◽

Vol 06 (02) ◽

pp. 065-071 ◽

Cited By ~ 1

Author(s):

Lovely Gupta ◽

Priti Lal ◽

Deepak Khandelwal

Keyword(s):

Diabetes Management ◽

Insulin Dose ◽

Nutrition Therapy ◽

Postprandial Blood Glucose ◽

Insulin Regimen ◽

Patient Centered ◽

Dietary Practices ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Central Pillar

AbstractDiverse dietary practices and nutritional counseling strategies are followed in the management of diabetes and its comorbidities. The dietary approaches practiced in India make use of calorie and nutrient counting to ensure patient-centered nutrition therapy in diabetes management. Macronutrient modulation is a central pillar of patient-centered medical nutrition therapy (MNT). Carbohydrates (CHO) are considered as the predominant macronutrient affecting postprandial blood glucose levels. The insulin-to-CHO ratio is used for calculating mealtime insulin doses among patients on insulin regimen. The aim of this article is to highlight challenges faced in planning MNT, modifying recommended dietary allowances for persons with diabetes, and suggesting solutions to overcome these. It also aims to understand the requirement of individual macronutrients and their impact on glycemia as well as insulin dose adjustment.

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An evaluation of randomized controlled trials on nutraceuticals containing traditional Chinese medicines for diabetes management: a systematic review

Chinese Medicine ◽

10.1186/s13020-019-0276-3 ◽

2019 ◽

Vol 14 (1) ◽

Cited By ~ 2

Author(s):

Junnan Shi ◽

Hao Hu ◽

Joanna Harnett ◽

Xiaoting Zheng ◽

Zuanji Liang ◽

...

Keyword(s):

Blood Glucose ◽

Randomized Controlled Trials ◽

Diabetes Management ◽

Fasting Blood Glucose ◽

Risk Of Bias ◽

Controlled Trials ◽

Glucose Levels ◽

Randomized Controlled ◽

Blood Glucose Levels

Abstract Background Nutraceuticals containing traditional Chinese medicine (TCM) are promoted for use in the management of diabetes. The evidence to support such use is largely unknown. This study aimed to summarise and evaluate the literature reporting the results of randomized controlled trials (RCTs) investigating the effects of nutraceuticals in people living with diabetes. Methods Literature from four electronic databases (PubMed, Scopus, CINAHL and Web of Science) was searched following PRISMA guidelines to yield RCT publications on nutraceutical for diabetes management published since 2009. The quality of reporting was assessed using the CONSORT 2010 checklist statement. Risk-of-bias for each study was assessed using the Cochrane risk of bias tool. Results Out of 1978 records identified in the initial search, 24 randomized, double/triple-blinded, controlled trials that investigated the effect of nutraceuticals covering 17 different TCM herbs for diabetes management were selected. Participants included people who were diabetic (n = 16), pre-diabetic (n = 3) or predisposed to diabetes (n = 5). Sample sizes ranged between 23 and 117 for 2 arms, or 99–165 for 3 arms. Comparisons were made against placebo (n = 22), conventional medicine (n = 1), or regular diet (n = 1) for a duration between 4 and 24 weeks. All but one study tested the effect on fasting blood glucose levels (n = 23) or glycated haemoglobin levels (n = 18), and/or postprandial 2-h blood glucose levels (n = 4) as the primary outcomes. Nineteen studies reported some statistically significant reductions in the respective measures while 5 studies showed no effect on primary or secondary outcomes. None of the included studies met all the criteria for the CONSORT guidelines. Incomplete reporting about randomization and blinding, and a lack of ancillary analyses to explore other influential factors and potential harms associated with the use were repeatedly noted. Based on the Cochrane risk-of-bias tool, 19 studies were deemed to have a high risk of bias mainly attributed to sponsor bias. Conclusions There is some evidence to suggest positive clinical outcomes in response to the administration of a range of nutraceuticals containing TCM in the management of diabetes. However, these results must be interpreted with caution due to the overall low quality of the trials.

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Cardiovascular effects of glucagon-like peptide 1 receptor agonists: from mechanistic studies in humans to clinical outcomes

Cardiovascular Research ◽

10.1093/cvr/cvz323 ◽

2019 ◽

Vol 116 (5) ◽

pp. 916-930 ◽

Cited By ~ 9

Author(s):

Valerie D Heuvelman ◽

Daniël H Van Raalte ◽

Mark M Smits

Keyword(s):

Cardiovascular Disease ◽

Blood Glucose ◽

Cardiovascular Effects ◽

Lifestyle Changes ◽

Mechanistic Studies ◽

Receptor Agonists ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Glucagon Like Peptide ◽

Glucagon Like Peptide 1

Abstract Type 2 diabetes mellitus (T2DM) is currently one of the most prevalent diseases, with as many as 415 million patients worldwide. T2DM is characterized by elevated blood glucose levels and is often accompanied by several comorbidities, such as cardiovascular disease. Treatment of T2DM is focused on reducing glucose levels by either lifestyle changes or medical treatment. One treatment option for T2DM is based on the gut-derived hormone glucagon-like peptide 1 (GLP-1). GLP-1 reduces blood glucose levels by stimulating insulin secretion, however, it is rapidly degraded, and thereby losing its glycaemic effect. GLP-1 receptor agonists (GLP-1RAs) are immune to degradation, prolonging the glycaemic effect. Lately, GLP-1RAs have spiked the interest of researchers and clinicians due to their beneficial effects on cardiovascular disease. Preclinical and clinical data have demonstrated that GLP-1 receptors are abundantly present in the heart and that stimulation of these receptors by GLP-1 has several effects. In this review, we will discuss the effects of GLP-1RA on heart rate, blood pressure, microvascular function, lipids, and inflammation, as measured in human mechanistic studies, and suggest how these effects may translate into the improved cardiovascular outcomes as demonstrated in several trials.

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The Juntos Pilot Study: A Diabetes Management Intervention for Latino Caregiving Dyads

The Diabetes Educator ◽

10.1177/0145721719866619 ◽

2019 ◽

Vol 45 (5) ◽

pp. 507-519 ◽

Cited By ~ 1

Author(s):

Carolyn A. Mendez-Luck ◽

Jeanne Miranda ◽

Carol M. Mangione ◽

Jangho Yoon ◽

Aurora VanGarde

Keyword(s):

Type 2 Diabetes ◽

Diabetes Management ◽

Lifestyle Changes ◽

Community Dwelling ◽

Mexican Origin ◽

Management Intervention ◽

Glucose Levels ◽

Dyadic Communication ◽

Latino Adults

Purpose The purpose of this study was to design a culturally sensitive dyad-level diabetes intervention to improve glycemic control for older Latino adults with type 2 diabetes. Methods This study used a pretest-posttest noncontrol group design. The intervention was developed from formative research with Mexican-origin caregiving dyads. The curriculum was adapted from 2 randomized trials of community interventions specifically designed for Latino older adults with type 2 diabetes. The curriculum consisted of communication skill-building exercises and dyad decision making on lifestyle changes to improve the older adult’s blood glucose levels. Thirty-two community-dwelling dyads completed a 6-week program of one-on-one sessions with a trained program facilitator. Main outcomes were feasibility and acceptability of the Juntos program. The authors assessed feasibility by examining participant burden and retention and acceptability by participant exit interviews. Although underpowered for outcomes, A1C, health status, and dyadic communication were also assessed to evaluate whether trends suggested the effectiveness of the intervention. Results Most participants viewed Juntos as an acceptable program and wanted the program expanded in terms of length and scope. All outcomes showed improvement from baseline through 6 months postintervention. Conclusions Results show that Juntos is acceptable to Mexican-origin caregiving dyads and is a promising approach for effectively controlling type 2 diabetes among older Latino adults who have a family caregiver.

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Mulberry leaf extract improves glycaemic response and insulaemic response to sucrose in healthy subjects: results of a randomized, double blind, placebo-controlled study

Nutrition & Metabolism ◽

10.1186/s12986-021-00571-2 ◽

2021 ◽

Vol 18 (1) ◽

Author(s):

Pariyarath Sangeetha Thondre ◽

Helen Lightowler ◽

Lis Ahlstrom ◽

Andrew Gallagher

Keyword(s):

Blood Glucose ◽

Leaf Extract ◽

Lifestyle Changes ◽

Glycaemic Response ◽

Double Blind ◽

Glucose Levels ◽

Mulberry Leaf ◽

Blood Glucose Levels ◽

Mulberry Leaf Extract ◽

White Mulberry

Abstract Background There are many benefits of maintaining healthy blood glucose levels, and studies have shown that lifestyle changes such as changes to diet can successfully restore normoglycaemia in participants with dysglycaemia. Significant health-related lifestyle changes are often difficult to implement and functional ingredients that can reduce glycaemic and insulaemic responses may help at risk populations. The aim of this study was to investigate whether a mulberry leaf extract could lower the glycaemic and insulinaemic responses to 75 g sucrose in healthy individuals. Methods A double-blind, randomised, placebo-controlled, crossover design trial was conducted by the Oxford Brookes Centre for Nutrition and Health. Thirty-eight participants were recruited into the trial and, after an overnight fast, were given 75 g sucrose + white mulberry leaf extract, or 75 g sucrose alone. Capillary blood samples were collected at 15-min intervals in the first hour and at 30-min intervals over the second hour to determine glucose and plasma insulin levels. Data analysis was conducted using a paired samples T test or a Wilcoxon signed rank test. Results The addition of mulberry leaf extract to sucrose resulted in a significantly lower glycaemic response and insulinaemic response compared to a matched placebo (sucrose alone). The change in blood glucose measurements were significantly lower at 15 min (p < 0.001), 30 min (p < 0.001), 45 min (p = 0.008), and 120 min (p < 0.001) and plasma insulin measurements were significantly lower at 15 min (p < 0.001), 30 min (p < 0.001), 45 min (p < 0.001), 60 min (p = 0.001) and 120 min (p < 0.001). The glucose iAUC (− 42%, p = 0.001), insulin iAUC (− 40%, p < 0.001), peak glucose (− 40.0%, p < 0.001) and peak insulin (− 41%, p < 0.001) from baseline were significantly lower for white mulberry leaf extract compared with the placebo. White mulberry leaf extract was well tolerated and there were no reported adverse events. Conclusions Mulberry leaf extract can be used as part of lifestyle changes that may lead to healthy blood glucose levels. Trial registration: ISRCTN99601810 (23 October 2020, retrospectively registered)

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The Beneficial Effects of SesaVitaTM on Lipid Profiles and Blood Glucose Levels in Subjects With Prediabetes and Mild-To-Moderate Hyperlipidemia in India

Journal of Food Research ◽

10.5539/jfr.v2n5p104 ◽

2013 ◽

Vol 2 (5) ◽

pp. 104 ◽

Cited By ~ 1

Author(s):

H. N. Shivaprasad ◽

M. Bhanumathy ◽

Ceyhun Tamer ◽

G. Sushma ◽

K. R. Raveendra ◽

...

Keyword(s):

Blood Glucose ◽

Lipid Profile ◽

Lifestyle Changes ◽

Secondary Outcome ◽

Oral Glucose ◽

Double Blind Study ◽

Beneficial Effects ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Normal Ranges

Individuals suffering from Type 2 diabetes develop prediabetes before progression of diabetes. In case of prediabetes people, the blood glucose levels are higher than normal but not sufficient to be diagnosed as diabetes. On the basis of existing reports on Sesame extract, SesaVitaTM which is an herbal food supplement containing Sesame seeds (Sesamum indicum L.) extract may provide an option for management of prediabetes. The objective of this study was to determine the beneficial effects of SesaVitaTM in prediabetes and mild to moderate hyperlipidemia subjects. This randomized, placebo-controlled, double-blind study comprised of 13 female and 07 male patients with prediabetes and mild to moderate hyperlipidemia, aged between 18 and 65 years. Twenty subjects were randomized to receive SesaVitaTM (500 mg/day) or placebo along with therapeutic lifestyle changes for 6 weeks. The primary outcome was the measure of efficacy in terms of change in serum lipid profile and glycaemic levels on week 3 and 6. Secondary outcome measures include safety and tolerability evaluated by physical examination and clinical laboratory evaluations. Improvements in lipid profile and glycaemic levels were observed in SesaVitaTM treated group when compared with placebo and baseline. A statistical significant reduction was observed in low density lipoprotein cholesterol (LDL-C), total cholesterol (TC), oral glucose tolerance test (OGTT) and fasting blood sugar (FBS) levels during week 3 and 6 when treated with SesaVitaTM extract. No adverse events occurred and all safety parameters were within normal ranges during the study. This study revealed that the treatment with SesaVitaTM was safe and well tolerated; may be beneficial in the management of prediabetes and mild-to-moderate hyperlipidemia.

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Correlation Between Blood Glucose Control And Decrease Of Peripheral Vascularization In Diabetes Mellitus Patient

Nurscope Jurnal Penelitian dan Pemikiran Ilmiah Keperawatan ◽

10.30659/nurscope.4.1.18-22 ◽

2018 ◽

Vol 4 (1) ◽

pp. 18

Author(s):

Fitria Endah Janitra ◽

Dinda Sandika

Keyword(s):

Diabetes Mellitus ◽

Blood Glucose ◽

Glucose Control ◽

Diabetes Management ◽

Blood Glucose Control ◽

Nursing Intervention ◽

Tissue Ischemia ◽

Control Blood Glucose ◽

Glucose Levels ◽

Blood Glucose Levels

Introduction: Diabetes mellitus (DM) is a metabolic disorder characterized by elevated blood glucose levels. Chronic complications of DM affect coronary circulation, peripheral vascularization, and blood vessels of the brain. Decrease in peripheral vascularization increases the risk of tissue ischemia and weakens functional status, therefore it is necessary to control blood glucose levels. Islam teaches to its believers to control their diet, where diet is one of the four pillars of diabetes management. Methodology: this is analytic descriptive research with cross sectional methods in 67 respondents taken by consecutive sampling technique. Results: There was a significant correlation within blood glucose control and decreased peripheral vascularization in DM patients (p-value 0.010). Discussion: need further research regarding nursing intervention to control blood glucose.

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Pharmacological management of psychiatric disorders in pregnancy complicated by diabetics

Journal of Social Health and Diabetes ◽

10.4103/2321-0656.130789 ◽

2014 ◽

Vol 02 (02) ◽

pp. 070-076

Author(s):

Yatan Balhara ◽

Rohit Verma ◽

Bharti Kalra

Keyword(s):

Psychiatric Disorders ◽

Diabetes Management ◽

Careful Selection ◽

Pharmacological Management ◽

Glucose Levels ◽

Additional Dimension ◽

Blood Glucose Levels ◽

Psychotropic Medicines ◽

Selection Of ◽

In Pregnancy

AbstractPregnancy has been identified as a biological, psychological and social stressor that predisposes women to emergence/re-emergence of psychiatric disorders. Effective pharmacological treatment is available for various psychiatric disorders. However, management of psychiatric disorders during pregnancy requires careful selection of the pharmacotherapeutic agent. Management of psychiatric disorders in pregnancy among diabetics brings in an additional dimension. The psychotropic medicines have been found to impact blood glucose levels and can interfere with diabetes management. This article reviews the available evidence on the use of psychotropic medicines in antenatal women with diabetes.

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Parent Perspectives of Diabetes Management in Schools

The Diabetes Educator ◽

10.1177/0145721708325155 ◽

2008 ◽

Vol 34 (6) ◽

pp. 996-1003 ◽

Cited By ~ 30

Author(s):

Farrah Jacquez ◽

Stacey Stout ◽

Rose Alvarez-Salvat ◽

Michelle Fernandez ◽

Manuela Villa ◽

...

Keyword(s):

Diabetes Care ◽

Diabetes Management ◽

Care Plan ◽

Management Support ◽

Minority Children ◽

White Children ◽

Glucose Levels ◽

Blood Glucose Levels ◽

Federal Laws ◽

To Receive

Purpose The purpose of this study is to investigate parent reports of the diabetes care support their children receive in school, their concerns about diabetes management in school, and their knowledge of federal laws that protect children with diabetes. In addition, the study explores ethnic and socioeconomic status differences in diabetes management in school. Methods An ethnically heterogeneous sample of 309 parents of children with diabetes was recruited from a community-based and a university-based diabetes outpatient clinic. Parents completed a survey assessing supports their child's school provides for diabetes care, worries about diabetes care in school, and awareness of federal laws that pertain to children with diabetes. Results Many children did not have a written care plan or a nurse at school, but significantly more white children had these supports than Hispanic or black children. Most children were not allowed to check blood glucose levels or administer insulin in class. Most parents were worried about hyperglycemia and hypoglycemia in school, and most were not at all or only a little confident in the school's ability to care for diabetes. Most parents were not aware of federal laws, but high-income and white parents were more likely to be aware. Conclusions According to parents in the current study, children receive inadequate diabetes management support in schools. Minority children are less likely to receive supports than white children. Parents are worried about diabetes management in school, but most do not have the knowledge of federal laws necessary to protect their children.

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