scholarly journals Pharmacological management of psychiatric disorders in pregnancy complicated by diabetics

2014 ◽  
Vol 02 (02) ◽  
pp. 070-076
Author(s):  
Yatan Balhara ◽  
Rohit Verma ◽  
Bharti Kalra
Keyword(s):  
Psychiatric Disorders ◽  
Diabetes Management ◽  
Careful Selection ◽  
Pharmacological Management ◽  
Glucose Levels ◽  
Additional Dimension ◽  
Blood Glucose Levels ◽  
Psychotropic Medicines ◽  
Selection Of ◽  
In Pregnancy

AbstractPregnancy has been identified as a biological, psychological and social stressor that predisposes women to emergence/re-emergence of psychiatric disorders. Effective pharmacological treatment is available for various psychiatric disorders. However, management of psychiatric disorders during pregnancy requires careful selection of the pharmacotherapeutic agent. Management of psychiatric disorders in pregnancy among diabetics brings in an additional dimension. The psychotropic medicines have been found to impact blood glucose levels and can interfere with diabetes management. This article reviews the available evidence on the use of psychotropic medicines in antenatal women with diabetes.

Modern technologies in diabetes management - continuous glucose monitoring and insulin pump therapy

2021 ◽  
Vol 87 (1) ◽  
pp. 50-55
Author(s):  
E.Yu. Pyankova ◽  
◽  
L.A. Anshakova ◽  
I.A. Pyankov ◽  
S.V. Yegorova ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Diabetes Management ◽  
Insulin Pump ◽  
Glucose Monitoring ◽  
Insulin Pump Therapy ◽  
Pump Therapy ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
The Individual ◽  
Glucose Lowering Therapy

The problems of complications of diabetes mellitus cannot be solved without constant monitoring of blood glucose levels. The evolution of additional technologies for the determination of glucose in the blood of the last decades makes it possible to more accurately predict the risks of complications, both in the individual and in the patient population as a whole. The article provides an overview of the methods used in modern diabetology, facilitating control over the variability of blood glucose levels and helping in a more accurate selection of glucose-lowering therapy. All presented methods are currently working in real clinical practice in the Khabarovsk Krai

scholarly journals Optimizing Macronutrients in People with Diabetes

2018 ◽  
Vol 06 (02) ◽  
pp. 065-071 ◽  
Author(s):  
Lovely Gupta ◽  
Priti Lal ◽  
Deepak Khandelwal
Keyword(s):  
Diabetes Management ◽  
Insulin Dose ◽  
Nutrition Therapy ◽  
Postprandial Blood Glucose ◽  
Insulin Regimen ◽  
Patient Centered ◽  
Dietary Practices ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Central Pillar

AbstractDiverse dietary practices and nutritional counseling strategies are followed in the management of diabetes and its comorbidities. The dietary approaches practiced in India make use of calorie and nutrient counting to ensure patient-centered nutrition therapy in diabetes management. Macronutrient modulation is a central pillar of patient-centered medical nutrition therapy (MNT). Carbohydrates (CHO) are considered as the predominant macronutrient affecting postprandial blood glucose levels. The insulin-to-CHO ratio is used for calculating mealtime insulin doses among patients on insulin regimen. The aim of this article is to highlight challenges faced in planning MNT, modifying recommended dietary allowances for persons with diabetes, and suggesting solutions to overcome these. It also aims to understand the requirement of individual macronutrients and their impact on glycemia as well as insulin dose adjustment.

scholarly journals Discrepancies Between Blood Glucose and Interstitial Glucose—Technological Artifacts or Physiology: Implications for Selection of the Appropriate Therapeutic Target

2017 ◽  
Vol 11 (4) ◽  
pp. 766-772 ◽  
Author(s):  
Thorsten Siegmund ◽  
Lutz Heinemann ◽  
Ralf Kolassa ◽  
Andreas Thomas
Keyword(s):  
Blood Glucose ◽  
Therapeutic Target ◽  
Diabetes Management ◽  
Glucose Monitoring ◽  
Blood Glucose Measurement ◽  
Glucose Measurement ◽  
Glucose Levels ◽  
Therapeutic Decisions ◽  
The Impact ◽  
Selection Of

Background: For decades, the major source of information used to make therapeutic decisions by patients with diabetes has been glucose measurements using capillary blood samples. Knowledge gained from clinical studies, for example, on the impact of metabolic control on diabetes-related complications, is based on such measurements. Different to traditional blood glucose measurement systems, systems for continuous glucose monitoring (CGM) measure glucose in interstitial fluid (ISF). The assumption is that glucose levels in blood and ISF are practically the same and that the information provided can be used interchangeably. Thus, therapeutic decisions, that is, the selection of insulin doses, are based on CGM system results interpreted as though they were blood glucose values. Methods: We performed a more detailed analysis and interpretation of glucose profiles obtained with CGM in situations with high glucose dynamics to evaluate this potentially misleading assumption. Results: Considering physical activity, hypoglycemic episodes, and meal-related differences between glucose levels in blood and ISF uncover clinically relevant differences that can make it risky from a therapeutic point of view to use blood glucose for therapeutic decisions. Conclusions: Further systematic and structured evaluation as to whether the use of ISF glucose is more safe and efficient when it comes to acute therapeutic decisions is necessary. These data might also have a higher prognostic relevance when it comes to long-term metabolic consequences of diabetes. In the long run, it may be reasonable to abandon blood glucose measurements as the basis for diabetes management and switch to using ISF glucose as the appropriate therapeutic target.

scholarly journals An evaluation of randomized controlled trials on nutraceuticals containing traditional Chinese medicines for diabetes management: a systematic review

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Junnan Shi ◽  
Hao Hu ◽  
Joanna Harnett ◽  
Xiaoting Zheng ◽  
Zuanji Liang ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Randomized Controlled Trials ◽  
Diabetes Management ◽  
Fasting Blood Glucose ◽  
Risk Of Bias ◽  
Controlled Trials ◽  
Glucose Levels ◽  
Randomized Controlled ◽  
Blood Glucose Levels

Abstract Background Nutraceuticals containing traditional Chinese medicine (TCM) are promoted for use in the management of diabetes. The evidence to support such use is largely unknown. This study aimed to summarise and evaluate the literature reporting the results of randomized controlled trials (RCTs) investigating the effects of nutraceuticals in people living with diabetes. Methods Literature from four electronic databases (PubMed, Scopus, CINAHL and Web of Science) was searched following PRISMA guidelines to yield RCT publications on nutraceutical for diabetes management published since 2009. The quality of reporting was assessed using the CONSORT 2010 checklist statement. Risk-of-bias for each study was assessed using the Cochrane risk of bias tool. Results Out of 1978 records identified in the initial search, 24 randomized, double/triple-blinded, controlled trials that investigated the effect of nutraceuticals covering 17 different TCM herbs for diabetes management were selected. Participants included people who were diabetic (n = 16), pre-diabetic (n = 3) or predisposed to diabetes (n = 5). Sample sizes ranged between 23 and 117 for 2 arms, or 99–165 for 3 arms. Comparisons were made against placebo (n = 22), conventional medicine (n = 1), or regular diet (n = 1) for a duration between 4 and 24 weeks. All but one study tested the effect on fasting blood glucose levels (n = 23) or glycated haemoglobin levels (n = 18), and/or postprandial 2-h blood glucose levels (n = 4) as the primary outcomes. Nineteen studies reported some statistically significant reductions in the respective measures while 5 studies showed no effect on primary or secondary outcomes. None of the included studies met all the criteria for the CONSORT guidelines. Incomplete reporting about randomization and blinding, and a lack of ancillary analyses to explore other influential factors and potential harms associated with the use were repeatedly noted. Based on the Cochrane risk-of-bias tool, 19 studies were deemed to have a high risk of bias mainly attributed to sponsor bias. Conclusions There is some evidence to suggest positive clinical outcomes in response to the administration of a range of nutraceuticals containing TCM in the management of diabetes. However, these results must be interpreted with caution due to the overall low quality of the trials.

scholarly journals Animal Models in Diabetes Mellitus: An Overview

2019 ◽  
Vol 9 (1-s) ◽  
pp. 472-475 ◽  
Author(s):  
Mudasir Maqbool ◽  
Mohmad Amin Dar ◽  
Imran Gani ◽  
Suhail Ahmad Mir
Keyword(s):  
Diabetes Mellitus ◽  
Animal Models ◽  
Animal Species ◽  
Experimental Models ◽  
Postprandial Blood Glucose ◽  
Genetic Manipulations ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Alloxan Monohydrate ◽  
Selection Of

Diabetes mellitus is defined as a state in which homeostasis of carbohydrate and lipid metabolism is improperly regulated by insulin. This results primarily in elevated fasting and postprandial blood glucose levels. If this imbalanced homeostasis dose not returns to normalcy and continues for a protracted period of time, it leads to hyperglycemia, which in due course turns into a syndrome called diabetes mellitus. Several animal models have been developed for studying diabetes mellitus or testing anti-diabetic agents. These models include chemical, surgical (pancreatectomy) and genetic manipulations in several animal species to induce diabetes mellitus. The diabetogenic drugs used include: Alloxan monohydrate, Streptozotocin with or without nicotinamide, Ferric nitrilotriacetate, Ditizona and Anti-insulin serum. The selection of these models to use for investigating the antidiabetic properties of a new compound may be a very difficult task especially for young researchers. The aim of the present review is give a brief idea about various experimental models developed for studying diabetes mellitus, assess the merits and demerits of each model and highlight the precautions needed to avoid erroneous results during the applications of these models. Keywords: Diabetes Mellitus, Animal models, Alloxan, Streptozotocin.

scholarly journals Correlation Between Blood Glucose Control And Decrease Of Peripheral Vascularization In Diabetes Mellitus Patient

2018 ◽  
Vol 4 (1) ◽  
pp. 18
Author(s):  
Fitria Endah Janitra ◽  
Dinda Sandika
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Glucose Control ◽  
Diabetes Management ◽  
Blood Glucose Control ◽  
Nursing Intervention ◽  
Tissue Ischemia ◽  
Control Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels

Introduction: Diabetes mellitus (DM) is a metabolic disorder characterized by elevated blood glucose levels. Chronic complications of DM affect coronary circulation, peripheral vascularization, and blood vessels of the brain. Decrease in peripheral vascularization increases the risk of tissue ischemia and weakens functional status, therefore it is necessary to control blood glucose levels. Islam teaches to its believers to control their diet, where diet is one of the four pillars of diabetes management. Methodology: this is analytic descriptive research with cross sectional methods in 67 respondents taken by consecutive sampling technique. Results: There was a significant correlation within blood glucose control and decreased peripheral vascularization in DM patients (p-value 0.010). Discussion: need further research regarding nursing intervention to control blood glucose.

scholarly journals Parent Perspectives of Diabetes Management in Schools

2008 ◽  
Vol 34 (6) ◽  
pp. 996-1003 ◽  
Author(s):  
Farrah Jacquez ◽  
Stacey Stout ◽  
Rose Alvarez-Salvat ◽  
Michelle Fernandez ◽  
Manuela Villa ◽  
...  
Keyword(s):  
Diabetes Care ◽  
Diabetes Management ◽  
Care Plan ◽  
Management Support ◽  
Minority Children ◽  
White Children ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Federal Laws ◽  
To Receive

Purpose The purpose of this study is to investigate parent reports of the diabetes care support their children receive in school, their concerns about diabetes management in school, and their knowledge of federal laws that protect children with diabetes. In addition, the study explores ethnic and socioeconomic status differences in diabetes management in school. Methods An ethnically heterogeneous sample of 309 parents of children with diabetes was recruited from a community-based and a university-based diabetes outpatient clinic. Parents completed a survey assessing supports their child's school provides for diabetes care, worries about diabetes care in school, and awareness of federal laws that pertain to children with diabetes. Results Many children did not have a written care plan or a nurse at school, but significantly more white children had these supports than Hispanic or black children. Most children were not allowed to check blood glucose levels or administer insulin in class. Most parents were worried about hyperglycemia and hypoglycemia in school, and most were not at all or only a little confident in the school's ability to care for diabetes. Most parents were not aware of federal laws, but high-income and white parents were more likely to be aware. Conclusions According to parents in the current study, children receive inadequate diabetes management support in schools. Minority children are less likely to receive supports than white children. Parents are worried about diabetes management in school, but most do not have the knowledge of federal laws necessary to protect their children.

scholarly journals The use of low-glycaemic index diets in diabetes control

2010 ◽  
Vol 104 (6) ◽  
pp. 797-802 ◽  
Author(s):  
D. E. Thomas ◽  
E. J. Elliott
Keyword(s):  
Blood Glucose ◽  
Glycaemic Control ◽  
Diabetes Management ◽  
Weighted Mean Difference ◽  
Blood Glucose Control ◽  
Glycaemic Index ◽  
Cochrane Library ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Improved Glycaemic Control

The aim of diabetes management is to normalise blood glucose levels since improved blood glucose control is associated with fewer complications. Food affects blood glucose levels; however, there is no universal approach to the optimal diabetic diet and there is controversy about the usefulness of the low-glycaemic index (GI) diet. To assess the effects of low-GI diets on glycaemic control in diabetes, we conducted electronic searches of the Cochrane Library, MEDLINE, EMBASE and CINAHL. We assessed randomised controlled trials (RCT) with interventions >4 weeks that compared a low-GI diet with a higher-GI diet for type 1 or type 2 diabetes. Twelve RCT (n612) were identified. There was a significant decrease in glycated Hb (HbA1c) with low-GI diet than with the control diet, indicating improved glycaemic control (seven trials,n457, weighted mean difference (WMD) − 0·4 % HbA1c, 95 % CI − 0·7, − 0·20,P = 0·001). In four studies reporting the results for glycaemic control as fructosamine, three of which were 6 weeks or less in duration, pooled data showed a decrease in fructosamine (WMD − 0·23 mmol/l, 95 % CI − 0·47, 0·00,P = 0·05),n141, with low-GI diet than with high-GI diet. Glycosylated albumin levels decreased significantly with low-GI diet, but not with high-GI diet, in one study that reported this outcome. Lowering the GI of the diet may contribute to improved glycaemic control in diabetes.

Treatment of pregnant insulin-dependent diabetic women

1986 ◽  
Vol 113 (3_Suppl) ◽  
pp. S74-S76 ◽  
Author(s):  
K. Fuhrmann
Keyword(s):  
Blood Glucose ◽  
Congenital Malformations ◽  
Blood Glucose Concentration ◽  
Normal Blood ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Insulin Dependent ◽  
Normal Blood Glucose ◽  
Insulin Dependent Diabetic ◽  
In Pregnancy

Abstract. The treatment of 620 insulin-dependent diabetic pregnant women is reported. The goal of treatment was to achieve a normal blood glucose concentration as soon as possibly during early, or even before pregnancy. When intensified conventional insulin therapy was started before conception, about 88% of the patients achieved normal blood glucose levels during the first weeks of pregnancy. In only about 20% of the pregnant diabetics without intensified preconceptional treatment a normal blood glucose level was obtained during their first hospitalization in pregnancy. The rate of congenital malformations was 1.1% in the former and 7.1% in the latter group.

scholarly journals A cross sectional screen for diabetes correlating physical activity and blood glucose levels

2019 ◽  
Vol 6 (9) ◽  
pp. 4094
Author(s):  
Kulshreshth Sinha ◽  
Andrea Pereira Kolla ◽  
Rakhi Bajpai ◽  
Varaprasad Kolla
Keyword(s):  
Physical Activity ◽  
Blood Glucose ◽  
Physical Inactivity ◽  
Diabetes Management ◽  
Rural Populations ◽  
Undiagnosed Diabetes ◽  
Activity Increase ◽  
Random Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels

Background: Diabetes, a chronic disease, is presently a rapidly growing epidemic globally. The risk of diabetes type 2 is greatly increasing with change in lifestyle factors, urbanization, high blood pressure, overweight or obesity, physical inactivity and poor diet. It’s one of the reasons for premature death and disability and the number of cases are drastically increasing every year.Methods: 81 subjects above 18 years of age were considered for the screening. Random blood glucose levels were tested using the Thyrocare Sugar scan glucometer strips. Physical activity data was collected using a questionnaire. Based on the extent of physical activity, the subjects we grouped into three different categories. Data was analyzed and expressed using basic statistical tools in MS Excel 2007.Results: 6.17% of the rural population of Kendri, with mean age 47.4 years, had undiagnosed diabetes. The mean blood glucose level in diabetes positive cases was 279.8 mg/dL. A correlation of random blood glucose levels of the subjects with the extent of their physical activity was observed, where a decrease in physical activity/increase in physical inactivity showed an increase in blood glucose levels.Conclusions: From our study we conclude that undiagnosed diabetes is prevalent amongst the rural populations of Kendri, Chhattisgarh and low physical activity correlated with an increase of blood glucose levels, suggesting an urgent need to create health awareness, with emphasis on increase in physical activity, literacy and diabetes management, obesity, specifically among the illiterate and underprivileged rural populations.

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