scholarly journals Chondrosarcoma of the Nasal Septum—A Rare Subsite: Case Report with Review of Literature

2021 ◽  
Vol 42 (05) ◽  
pp. 506-509
Author(s):  
Nidhi Gupta ◽  
Awadhesh Kumar Pandey ◽  
Kislay Dimri ◽  
Surinder K Singhal ◽  
Neeraj Rathee ◽  
...  
Keyword(s):  
Nasal Septum ◽  
Malignant Tumors ◽  
Surgical Excision ◽  
Metastatic Potential ◽  
Young Female ◽  
Resection Margins ◽  
Diagnostic Dilemma ◽  
Complete Surgical Excision ◽  
Grade Ii ◽  
Common Primary Malignant Bone

AbstractChondrosarcomas are the second most common primary malignant bone tumors. Head and neck chondrosarcomas constitute less than 10% of these tumors, rarely arising from the nasal septum. These are locally aggressive malignant tumors arising from the cartilaginous framework of the nasal septum. Rarity of the tumor coupled with nonspecific symptoms makes it a diagnostic dilemma. Diagnosis requires endoscopy, radiology, and final histopathology for confirmation. Treatment is mainly surgical, requiring complete surgical excision with clear margins. Radiation has a role in unresectable tumors or for tumors with positive margins after surgery. Survival depends on the grade of tumor that predicts the metastatic potential of the tumor. We present a rare case of chondrosarcoma arising from the nasal septum in a 29-year-old young female presenting with complaints of nasal obstruction. Computed tomography was suggestive of a calcified cartilaginous tumor arising from the nasal septum. Endoscopic excision was done and postoperative histopathology showed grade II chondrosarcoma with clear margins. No adjuvant treatment was given to our patient and 2 years post-excision patient is disease free.To conclude, chondrosarcoma of the nasal septum is a rare tumor, with nonspecific symptoms. Surgery with clear margins remains the treatment of choice. Prognosis depends on the extent of tumor at presentation, resection margins, and grade of tumor.

scholarly journals Localized Castleman’s Disease in Retroperitoneum Mimicking Broad Ligament Leiomyoma – a Diagnostic Challenge

2016 ◽  
Vol 10 (2) ◽  
pp. 57-59
Author(s):  
S Gon ◽  
D Mallik ◽  
A Bhattacharya ◽  
B Majumdar ◽  
M Sengupta
Keyword(s):  
Broad Ligament ◽  
Castleman’S Disease ◽  
Surgical Excision ◽  
Young Female ◽  
Castleman Disease ◽  
Castleman's Disease ◽  
Diagnostic Challenge ◽  
Diagnostic Dilemma ◽  
Vascular Type ◽  
Complete Surgical Excision

Primary retroperitoneal tumours pose a diagnostic dilemma and therapeutic challenges because of their location and late detection. Localized Castleman Disease (CD) in retroperitoneal location is a rare occurrence, with incidence of only 4% cases occurring in diverse locations like retroperitoneum. A rare case of unicentric localized Castleman Disease localized in broad ligament is hereby reported which was clinically & radiologically suspected as broad ligament leiomyoma but finally diagnosed as Castleman’s Disease, hyaline vascular type in a young female posing a diagnostic challenge both for the pathologist and clinician. Definite diagnosis is essential as complete surgical excision in case of unicentric Castleman’s Disease has good prognosis after resection.   

scholarly journals Diagnostic Dilemma of a Rare, Giant Retroperitoneal Schwannoma: A Case Report and Review of Literature

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Mahendra Singh ◽  
Lovekesh Kumar ◽  
Rajkumar Chejara ◽  
Om Prakash Prasad ◽  
Yuvraj Kolhe ◽  
...  
Keyword(s):  
Low Frequency ◽  
Surgical Excision ◽  
Abdominal Distension ◽  
Exploratory Laparotomy ◽  
Postoperative Recovery ◽  
Cystic Mass ◽  
Imaging Features ◽  
Diagnostic Dilemma ◽  
Complete Surgical Excision ◽  
Retroperitoneal Schwannoma

Schwannoma is a benign tumour of peripheral nerve sheath. It usually arises from head, neck, and trunk. Retroperitoneal schwannoma is a rare entity, accounting for only 0.3–3% of total schwannomas. Majority of retroperitoneal schwannomas reported in literature have a diameter of 5 to 15 cm. Preoperative diagnosis is difficult due to low frequency, nonspecific clinical course, and nonspecific imaging features. Histology usually provides definitive diagnosis. Schwannomas are solitary, well-circumscribed, and noninvasive, so complete surgical excision provides good result. We report a case of a 23-year-old male, who presented with progressive abdominal distension and intermittent episodes of intestinal obstruction. CECT was suggestive of huge solid-cystic mass in abdominopelvic region. Image guided percutaneous aspiration revealed around 1 litre of frank pus and FNAC was suggestive of abscess. Exploratory laparotomy revealed a large 32 × 28 × 26 cm mass with solid and cystic components containing 1 litre of pus. Histological features of tumour were suggestive of benign schwannoma and immunohistochemistry for S-100 was positive. Postoperative recovery was uneventful. We report this case of a retroperitoneal schwannoma because of giant size, rare location, unusual presentation, and diagnostic dilemma.

scholarly journals Giant lipoma of breast-a diagnostic dilemma

2021 ◽  
Vol 8 (2) ◽  
pp. 752
Author(s):  
D. J. Balsarkar ◽  
Sachin A. Suryawanshi ◽  
Muna Shaikh ◽  
Sudhir Dhobale
Keyword(s):  
Phyllodes Tumor ◽  
Surgical Excision ◽  
Needle Aspiration ◽  
Left Breast ◽  
Normal Breast ◽  
Diagnostic Challenge ◽  
Diagnostic Dilemma ◽  
Common Benign Tumor ◽  
Complete Surgical Excision ◽  
Giant Lipoma

Lipoma is the most common benign tumor of adipose tissue. Giant lipoma of breast is very rare.Majority of them are small in size, slow growing and asymptomatic until they reach large size. Most patients seek medical advice due to asymmetry in the breast and due to fear of malignancy. Breast lipomas pose a diagnostic challenge due to similarity of their texture to normal breast parenchyma and make it difficult to distinguish from other common breast lesions. The clinical and radiographic identification of breast lipoma remains challenging. Complete surgical excision with the capsule is essential to prevent recurrence. Breast reconstruction may require, to prevent asymmetry following surgical excision of giant breast lipoma. High degree of clinical suspicion and histolopathological correlation will help in preopertaive diagnosis of this clinical condition. Here, we report a case 50- year -old woman with left breast lump which clinically, radiologically and on fine needle aspiration cytology was diagnosed as phyllodes tumor, but after surgical excision it was reported as breast lipoma on final histopathology.

scholarly journals Nodular Fasciitis in a One-Year-Old Male: A Diagnostic Dilemma

2010 ◽  
Vol 25 (2) ◽  
pp. 27-31
Author(s):  
Adrian F. Fernando ◽  
Antonio H. Chua ◽  
Lily L. Sia-Vargas
Keyword(s):  
Neck Region ◽  
Aggressive Fibromatosis ◽  
Surgical Excision ◽  
University Hospital ◽  
Ground Substance ◽  
Nodular Fasciitis ◽  
High Resolution Computed Tomography ◽  
Diagnostic Dilemma ◽  
Complete Surgical Excision ◽  
One Year

Objective:  To present a rare case of nodular fasciitis presenting as a supra-auricular mass.   Methods: Design: Case Report Setting: Private Tertiary University Hospital Patient: One   Results: A one-year-old boy presented with an initially painless, left supra-auricular mass that rapidly enlarged from < 1 cm to 3 cm (widest diameter) in a two-month period. Sarcoma was initially considered over an inflammatory process as the mass was non-responsive to antibiotic therapy. Fine-Needle Aspiration Cytology (FNAC) and High-Resolution Computed Tomography (HRCT) with contrast revealed benign cytologic and radiologic findings making nodular fasciitis the primary impression.               The patient eventually underwent complete surgical excision of the left supra-auricular mass. Histopathologic findings then showed a stroma rich in collagen and myxoid ground substance and loose array of short S-shaped fascicle cells with scattered lymphocytes, macrophages and red blood cells consistent with nodular fasciitis.   Conclusion: Nodular fasciitis is a rare benign myofibroblastic soft tissue tumor which typically presents as a rapidly progressive nodular lesion in the head and neck region of the young pediatric age group. Cytopathologic recognition with FNA is a challenge. The gold standard of treatment is still surgical and in most reported cases, curative. More importantly, early clinical recognition and correlation with radiologic and histopathologic appearance is very important to avoid unnecessary work-ups and over-treatment.   Keywords: Nodular fasciitis; pseudosarcomatous fasciits; aggressive fibromatosis, desmoid tumor

Recurrence Rates and Sites for Grade II Canine Cutaneous Mast Cell Tumors Following Complete Surgical Excision

2002 ◽  
Vol 38 (1) ◽  
pp. 71-73 ◽  
Author(s):  
Chick Weisse ◽  
Frances S. Shofer ◽  
Karin Sorenmo
Keyword(s):  
Mast Cell ◽  
Tumor Recurrence ◽  
Surgical Excision ◽  
Adjuvant Radiation ◽  
Recurrence Rates ◽  
Mast Cell Tumors ◽  
Complete Surgical Excision ◽  
Grade Ii ◽  
Cutaneous Mast Cell ◽  
Distant Tumor

A retrospective study was performed on 31 dogs with completely excised, grade II, cutaneous mast cell tumors in order to determine recurrence rates and sites. Distant tumor recurrence developed in 22% of dogs, and local tumor recurrence developed in 11% of dogs; however, the vast majority of these animals were incompletely staged initially. Complete surgical excision of grade II mast cell tumors was associated with effective local control in 89% of these dogs. Therefore, adjuvant radiation therapy might not be indicated in the majority of dogs with complete surgical excision.

Primary Leiomyosarcoma of the Pancreas

2001 ◽  
Vol 125 (1) ◽  
pp. 152-155
Author(s):  
Gabriella Nesi ◽  
Desiree Pantalone ◽  
Ilaria Ragionieri ◽  
Andrea Amorosi
Keyword(s):  
Smooth Muscle ◽  
World Literature ◽  
Soft Tissues ◽  
Malignant Tumors ◽  
Smooth Muscle Actin ◽  
Surgical Excision ◽  
High Rate ◽  
Complete Surgical Excision ◽  
Membrane Components ◽  
Primary Leiomyosarcoma

Abstract Primary leiomyosarcoma of the pancreas is a rare tumor for which only 21 reports appear in the world literature. We describe an additional case of pancreatic leiomyosarcoma in a 76-year-old man, who complained of persistent high fever. Histologic examination revealed a pleomorphic spindle cell tumor. Reactivity for muscle-specific actin, α-smooth muscle actin, and basement membrane components, along with negative staining for epithelial and neural markers, were consistent with a smooth muscle sarcoma. The patient died of disease 1 year after complete surgical excision. This report highlights the need to use a complete antibody panel in order to accurately immunophenotype pleomorphic malignant tumors of the pancreas. A review of the cases compiled in the literature indicates that pancreatic leiomyosarcoma, like its counterpart arising in deep soft tissues, is an aggressive neoplasm characterized by short survival and a high rate of metastases.

scholarly journals Dermatofibrosarcoma Protuberans: Update on the Diagnosis and Treatment

2020 ◽  
Vol 9 (6) ◽  
pp. 1752 ◽  
Author(s):  
Xingpei Hao ◽  
Steven D. Billings ◽  
Fangbai Wu ◽  
Todd W. Stultz ◽  
Gary W. Procop ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Soft Tissue ◽  
Malignant Tumors ◽  
Dermatofibrosarcoma Protuberans ◽  
Surgical Excision ◽  
Clinical Staging ◽  
Surveillance Program ◽  
Fusion Transcripts ◽  
Complete Surgical Excision ◽  
High Local Recurrence Rate

Dermatofibrosarcoma protuberans (DFSP) is a slow growing, low- to intermediate-grade dermal soft-tissue tumor. It has a high local recurrence rate but low metastatic potential. It is characterized by a uniform spindle cell arrangement, classically with a storiform pattern and CD34 immunoreactivity. The histomorphology and immunophenotype overlap with a broad range of other neoplasms. The standard treatment is complete surgical excision. The surgical procedures include wide local excision (WLE) with tumor free margins, Mohs micrographic surgery (MMS) and amputation. Unresectable DFSPs are treated with radiation therapy and/or targeted therapy. DFSP has characteristic t(17; 22) (q22; q13), resulting in a COL1A1- PDGFB fusion transcripts in more than 90% of DFSPs. Molecular detection of the gene rearrangement or fusion transcripts is helpful for the diagnosis of patients with atypical morphology and for screening candidates for targeted therapy with tyrosine kinase inhibitors. The aims of the present review are to update the clinical presentation, tumorigenesis and histopathology of DFSP and its variants for diagnosis and differential diagnosis from other benign and malignant tumors, to compare the advantages and drawbacks of WLE and MMS, to propose the baseline for selecting surgical procedure based on tumor’s location, size, stage and relationship with surrounding soft tissue and bone structures, and to provide a biologic rationale for the systemic therapy. We further propose a modified clinical staging system of DFSP and a surveillance program for the patients after surgical excision.

scholarly journals Nasal Septal Angioleiomyoma and Septal Sinus Surgery: A Review of 2 Cases

2021 ◽  
pp. 014556132199132
Author(s):  
Gabriele Noreikaite ◽  
Sihun A. Kim ◽  
Adelaide Horcher
Keyword(s):  
Smooth Muscle ◽  
Nasal Septum ◽  
Surgical Excision ◽  
Sinus Surgery ◽  
Rare Tumor ◽  
Imaging Findings ◽  
Nasal Surgery ◽  
Single Institution ◽  
Complete Surgical Excision ◽  
High Index Of Suspicion

Angioleiomyomas are smooth muscle masses originating from blood vessel tunica media. This is a rare tumor, comprising less than 1% of benign sinonasal cavity tumors. Failure to recognize and surgically excise nasal angioleiomyomas can result in lesion recurrence. We present 2 new cases of nasal septum angioleiomyoma at a single institution. Additionally, both cases underwent septal and nasal surgery. Due to the nonspecific clinical and imaging findings, a high index of suspicion is needed to diagnose nasal septum angioleiomyoma, often requiring histopathological verification. Preferred treatment is complete surgical excision. From our experience, concurrent corrective septal and sinus surgery can be completed with tumors less than 1.0 cm in size.

Nasal septal carcinoma: initial symptom of nasal septal perforation

1988 ◽  
Vol 102 (9) ◽  
pp. 834-835 ◽  
Author(s):  
M. Echeverria-Zumarraga ◽  
C. Kaiser ◽  
C. Gavilan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Differential Diagnosis ◽  
Nasal Septum ◽  
Early Stage ◽  
Surgical Excision ◽  
Young Female ◽  
Initial Symptom ◽  
Primary Squamous Cell Carcinoma ◽  
Septal Perforation ◽  
Nasal Septal Perforation

AbstractA case of a primary squamous cell carcinoma of the nasal septum in a young female with initial symptom of septal perforation is reported. Carcinoma of the nasal septum is an uncommon entity and there are a few cases reported in the literature. The functional impact of their treatment and the high mortality makes it important to diagnose it at early stage. We discuss the differential diagnosis of septal perforation and recommend early wide surgical excision.

scholarly journals Septal pyogenic granuloma: a continuing riddle

2021 ◽  
Vol 7 (12) ◽  
pp. 1947
Author(s):  
Vaishnav Radhakrishnan ◽  
Sowmya Gajapathy ◽  
Priyanka Thangaraj ◽  
Jayita Das Poduval
Keyword(s):  
Squamous Cell Carcinoma ◽  
Nasal Septum ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Pyogenic Granuloma ◽  
Young Female ◽  
Vascular Lesion ◽  
Complete Resection ◽  
Granulomatous Lesions ◽  
Mucous Membranes

<p class="abstract">Pyogenic granuloma (PG) is a benign vascular lesion of the skin and mucous membranes commonly affecting the head and neck but less common in the nasal septum. Septal PG and can present with epistaxis and nasal obstruction. It is also called a lobular capillary hemangiomas (LCH) as histologically, pyogenic granuloma consists of circumscribed aggregates of capillaries arranged in lobules. Granulomatous lesions like Wegners granulomatosis, sarcoidosis and also tumours like squamous cell carcinoma, malignant melanoma can all mimic a septal PG. Surgical excision is the treatment of choice and diagnosis can be confirmed by histopathological examination. Complete resection can decrease the rates of recurrence. Here we reported a case of pyogenic granuloma of the nasal septum in a young female patient.</p>

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