Thyrotropin-Releasing Hormone Increases Plasma Levels of Glucagon, Insulin, Glucose and Free Fatty Acids in Rabbits

1981 ◽  
Vol 13 (07) ◽  
pp. 371-375 ◽  
Author(s):  
J. Knudtzon
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Plasma Levels ◽  
Thyrotropin Releasing Hormone ◽  
Releasing Hormone

Plasma levels of free fatty acids correlate with type 2 diabetes mellitus

2018 ◽  
Vol 20 (11) ◽  
pp. 2661-2669 ◽  
Author(s):  
Sandro Spiller ◽  
Matthias Blüher ◽  
Ralf Hoffmann
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Fatty Acids ◽  
Type 2 Diabetes Mellitus ◽  
Free Fatty Acids ◽  
Plasma Levels

Hormonal dose–response to an adenosine receptor agonist

1994 ◽  
Vol 72 (2) ◽  
pp. 113-116 ◽  
Author(s):  
Jacques LeBlanc ◽  
Julie Soucy
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Adenosine Receptor ◽  
Plasma Levels ◽  
Receptor Agonist ◽  
Insulin Response ◽  
Male Rats ◽  
Normal Ranges ◽  
Adenosine Receptor Agonist ◽  
Pituitary Adrenal Axis

The effect of various doses of i.p. injection of the adenosine receptor agonist (R)-phenylisopropyladenosine (R-PIA), ranging from nanomolar to micromolar concentrations, on plasma levels of free fatty acids, glucose, insulin, glucagon, ACTH, and corticosterone was examined in 200-g male rats. At the lowest dose of R-PIA (0.005 μmol/kg), a marked decrease in plasma insulin and free fatty acids was observed. This effect on free fatty acids persisted up to the highest concentration of R-PIA (50 μmol/kg). The insulin response showed a similar pattern except at the highest concentration, when the plasma levels were within normal ranges. A 100% increase in plasma glucose was found, but only with doses of 0.5 μmol/kg and above, suggesting an A2 receptor influence, possibly related to the elevation of plasma glucagon observed with the same doses of R-PIA. It has been shown that caffeine, an antagonist of adenosine, stimulates the pituitary–adrenal axis. Surprisingly, it was shown that R-PIA produces the same effect, as evidenced by the marked elevation of both plasma ACTH and corticosterone at concentrations of 0.5 μmol/kg and higher. It is suggested that this centrally mediated effect is due to a primary peripheral action.Key words: adenosine, glucose, free fatty acids, insulin, glucagon, ACTH, corticosterone.

Effects of Graded Insulin Infusions on Plasma Levels of Free Fatty Acids, Adrenaline and Noradrenaline Directly After Open Heart Surgery

1987 ◽  
Vol 35 (02) ◽  
pp. 96-100 ◽  
Author(s):  
F. Nilsson ◽  
E. Berglin W-O ◽  
R. Ekroth ◽  
G. Holm ◽  
I. Milocco ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Free Fatty Acids ◽  
Plasma Levels ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Open Heart
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