scholarly journals Effects of channel geometry and physicochemical properties of solutions on stable double emulsion production in planar microfluidic devices having triangular orifices

AIP Advances ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 065219
Author(s):  
Ruri Hidema ◽  
Ryotaro Ohashi ◽  
Susan J. Muller ◽  
Hiroshi Suzuki
2019 ◽  
Vol 39 (6) ◽  
pp. 888-902 ◽  
Author(s):  
Hyerin Shin ◽  
Hyo Tae Kim ◽  
Mi-Jung Choi ◽  
Eun-Young Ko

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Sidra Waheed ◽  
Joan M. Cabot ◽  
Niall P. Macdonald ◽  
Umme Kalsoom ◽  
Syamak Farajikhah ◽  
...  

Lab on a Chip ◽  
2009 ◽  
Vol 9 (5) ◽  
pp. 677-685 ◽  
Author(s):  
James V. Green ◽  
Tatiana Kniazeva ◽  
Mehdi Abedi ◽  
Darshan S. Sokhey ◽  
Mohammad E. Taslim ◽  
...  

Micromachines ◽  
2019 ◽  
Vol 10 (9) ◽  
pp. 593 ◽  
Author(s):  
Susana O. Catarino ◽  
Raquel O. Rodrigues ◽  
Diana Pinho ◽  
João M. Miranda ◽  
Graça Minas ◽  
...  

Since the first microfluidic device was developed more than three decades ago, microfluidics is seen as a technology that exhibits unique features to provide a significant change in the way that modern biology is performed. Blood and blood cells are recognized as important biomarkers of many diseases. Taken advantage of microfluidics assets, changes on blood cell physicochemical properties can be used for fast and accurate clinical diagnosis. In this review, an overview of the microfabrication techniques is given, especially for biomedical applications, as well as a synopsis of some design considerations regarding microfluidic devices. The blood cells separation and sorting techniques were also reviewed, highlighting the main achievements and breakthroughs in the last decades.


Author(s):  
Walter Gonzalez-Domenzain ◽  
Ashwin A. Seshia

This paper describes a microfabrication process for constructing three-dimensional microfluidic structures in polydimethylsiloxane (PDMS). Rapid prototyping of microfluidic devices is possible starting from ink-jet printed masks and by utilising replica molding to create fluidic structures in PDMS from SU-8 and SPR-220 masters pre-patterned on a silicon or glass substrate. Multi-layer bonded and stacked alignment of up to 13 different functional polymer microfluidic layers with through-layer fluidic interconnects has been demonstrated. Pneumatically actuated valves have also been demonstrated for the regulation of sub-10 nL of fluid volumes. The geometric design of the valves is described with experimental verification conducted on rounded and vertical channel profiles to examine the effects of channel geometry on valve leak rates. The PDMS-based technology allows for the fabrication of devices with extremely small reaction volumes and parallel sample processing, making these devices ideally suited to applications which require high throughput processing and the ability to conduct parallel assays with very limited volumes of reagent and sample. We describe the applications of this technology to protein crystallization in particular.


Lab on a Chip ◽  
2020 ◽  
Vol 20 (1) ◽  
pp. 147-154 ◽  
Author(s):  
Saraf Nawar ◽  
Joshuah K. Stolaroff ◽  
Congwang Ye ◽  
Huayin Wu ◽  
Du Thai Nguyen ◽  
...  

We present a multilayer dropmaker geometry that enables the modular fabrication of microfluidic devices containing precisely patterned channel surface wettability. The platform is used for the scalable production of uniform double emulsion drops.


RSC Advances ◽  
2016 ◽  
Vol 6 (31) ◽  
pp. 25927-25933 ◽  
Author(s):  
Shunbo Li ◽  
Xiuqing Gong ◽  
Ciara S. Mc Nally ◽  
Muling Zeng ◽  
Thembaninkosi Gaule ◽  
...  

This article presents a simple and highly reliable method for preparing PDMS microfluidic double emulsion devices that employs a single-step oxidative plasma treatment to both pattern the wettability of the microchannels and to bond the chips.


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