Effect of feed quality and stage of lactation on the concentration of glucose in the blood of lactating cattle

1977 ◽  
Vol 28 (2) ◽  
pp. 341 ◽  
Author(s):  
TJ McClure

Three groups of dairy cows were fed on: (i) immature forage oats, together with hay and dairy meal (ration A), or (ii) moderately mature forage oats alone (ration B), or (iii) relatively mature forage oats supplemented with dairy meal (ration C), from 2 weeks before until 10 weeks after parturition. The mean concentration of glucose in the blood of the cows fed on ration A did not fall significantly after parturition, but did fall significantly after parturition in the blood of cows on rations B and C. There appeared to be an interaction between feed quality and the stage of lactation in their effects on blood glucose concentration.

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Khaled El-Radaideh ◽  
Ala’’a Alhowary ◽  
Mohammad Alsawalmeh ◽  
Ahmed Abokmael ◽  
Haitham Odat ◽  
...  

Background. This prospective study compared the blood glucose concentration with spinal anesthesia or general anesthesia in patients undergoing elective cesarean section surgery. Methods. In total, 58 pregnant women who underwent elective cesarean section surgery were included in this prospective comparative study. Group S (n = 35) included patients who chose spinal anesthesia, and group G (n = 23) included patients who chose general anesthesia. The patients were allocated to the groups upon patients’ preference. For the group G, the blood glucose concentration (BGC) was obtained 5 minutes before induction, T1, and 5 minutes after induction T2. For the group S, the BGC was obtained immediately before the injection of the local anesthetic agent T1 and 5 minutes after the complete block T2. For both groups, BGC was measured 5 minutes before the end of surgery T3 and 30 minutes after the end of surgery T4. For BGC measurements, we used a blood glucose monitoring system with a lancet device to prick the finger. Results. There was no statistically significant difference in the mean blood glucose concentration between the groups S and G in T1 (78.3 ± 18.2 vs. 74.3 ± 14.7, p>0.05) and T2 (79.2 ± 18.3 vs. 84.9 ± 23.7, p>0.05). The mean BGC was statistically significantly higher in group G in comparison to group S in the times 5 minutes before (80.2 ± 18.1 vs. 108.4 ± 16.7, p<0.05) and 30 minutes after the end of surgery (80.9 ± 17.7 vs. 121.1 ± 17.4, p<0.05). Conclusion. There is a much lower increase in blood glucose concentration under spinal anesthesia than under general anesthesia. It is reasonable to suggest that the blood sugar concentration must be intraoperatively monitored in patients undergoing general anesthesia.


Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2647 ◽  
Author(s):  
Celeste Keesing ◽  
Brianna Mills ◽  
Charlene Rapsey ◽  
Jillian Haszard ◽  
Bernard Venn

We aimed to investigate the isolated effect of glycaemia on cognitive test performance by using beverages sweetened with two different glucose–fructose disaccharides, sucrose and isomaltulose. In a randomised crossover design, 70 healthy adults received a low-glycaemic-index (GI) isomaltulose and sucralose beverage (GI 32) and a high-GI sucrose beverage (GI 65) on two occasions that were separated by two weeks. Following beverage ingestion, declarative memory and immediate word recall were examined at 30, 80 and 130 min. At 140 min, executive function was tested. To confirm that the glycaemic response of the test beverages matched published GI estimates, a subsample (n = 12) of the cognitive testing population (n = 70) underwent glycaemic response testing on different test days. A significantly lower value of mean (95% CI) blood glucose concentration incremental area under the curve (iAUC) was found for isomaltulose, in comparison to the blood glucose concentration iAUC value for sucrose, the difference corresponding to −44 mmol/L∙min (−70, −18), p = 0.003. The mean (95% CI) difference in numbers of correct answers or words recalled between beverages at 30, 80 and 130 min were 0.1 (−0.2, 0.5), −0.3 (−0.8, 0.2) and 0.0 (−0.5, 0.5) for declarative memory, and −0.5 (−1.4, 0.3), 0.4 (−0.4, 1.3) and −0.4 (−1.1, 0.4) for immediate free word recall. At 140 min, the mean difference in the trail-making test between beverages was −0.3 sec (−6.9, 6.3). None of these differences were statistically or clinically significant. In summary, cognitive performance was unaffected by different glycaemic responses to beverages during the postprandial period of 140 min.


Mathematics ◽  
2021 ◽  
Vol 9 (20) ◽  
pp. 2529
Author(s):  
Gustavo A. Alonso-Silverio ◽  
Víctor Francisco-García ◽  
Iris P. Guzmán-Guzmán ◽  
Elías Ventura-Molina ◽  
Antonio Alarcón-Paredes

The present study comprises a comparison of the Mel Frequency Cepstral Coefficients (MFCC), Principal Component Analysis (PCA) and Independent Component Analysis (ICA) as feature extraction methods using ten different regression algorithms (AdaBoost, Bayesian Ridge, Decision Tree, Elastic Net, k-NN, Linear Regression, MLP, Random Forest, Ridge Regression and Support Vector Regression) to quantify the blood glucose concentration. A total of 122 participants—healthy and diagnosed with type 2 diabetes—were invited to be part of this study. The entire set of participants was divided into two partitions: a training subset of 72 participants, which was intended for model selection, and a validation subset comprising the remaining 50 participants, to test the selected model. A 3D-printed chamber for providing a light-controlled environment and a low-cost microcontroller unit were used to acquire optical measurements. The MFCC, PCA and ICA were calculated by an open-hardware computing platform. The glucose levels estimated by the system were compared to actual glucose concentrations measured by venipuncture in a laboratory test, using the mean absolute error, the mean absolute percentage error and the Clarke error grid for this purpose. The best results were obtained for MCCF with AdaBoost and Random Forest (MAE = 11.6 for both).


2014 ◽  
Vol 307 (4) ◽  
pp. H587-H597 ◽  
Author(s):  
Mark W. Sims ◽  
James Winter ◽  
Sean Brennan ◽  
Robert I. Norman ◽  
G. André Ng ◽  
...  

While it is well established that mortality risk after myocardial infarction (MI) increases in proportion to blood glucose concentration at the time of admission, it is unclear whether there is a direct, causal relationship. We investigated potential mechanisms by which increased blood glucose may exert cardiotoxicity. Using a Wistar rat or guinea-pig isolated cardiomyocyte model, we investigated the effects on cardiomyocyte function and electrical stability of alterations in extracellular glucose concentration. Contractile function studies using electric field stimulation (EFS), patch-clamp recording, and Ca2+ imaging were used to determine the effects of increased extracellular glucose concentration on cardiomyocyte function. Increasing glucose from 5 to 20 mM caused prolongation of the action potential and increased both basal Ca2+ and variability of the Ca2+ transient amplitude. Elevated extracellular glucose concentration also attenuated the protection afforded by ischemic preconditioning (IPC), as assessed using a simulated ischemia and reperfusion model. Inhibition of PKCα and β, using Gö6976 or specific inhibitor peptides, attenuated the detrimental effects of glucose and restored the cardioprotected phenotype to IPC cells. Increased glucose concentration did not attenuate the cardioprotective role of PKCε, but rather activation of PKCα and β masked its beneficial effect. Elevated extracellular glucose concentration exerts acute cardiotoxicity mediated via PKCα and β. Inhibition of these PKC isoenzymes abolishes the cardiotoxic effects and restores IPC-mediated cardioprotection. These data support a direct link between hyperglycemia and adverse outcome after MI. Cardiac-specific PKCα and β inhibition may be of clinical benefit in this setting.


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