scholarly journals Different effects of diets rich in olive oil, rapeseed oil and sunflower-seed oil on postprandial lipid and lipoprotein concentrations and on lipoprotein oxidation susceptibility

2002 ◽  
Vol 87 (5) ◽  
pp. 489-499 ◽  
Author(s):  
Nina S. Nielsen ◽  
Anette Pedersen ◽  
Brittmarie Sandström ◽  
Peter Marckmann ◽  
Carl-Erik Høy
Keyword(s):  
Olive Oil ◽  
Sunflower Seed ◽  
Rapeseed Oil ◽  
Seed Oil ◽  
Propagation Rate ◽  
Lag Time ◽  
Ldl Oxidation ◽  
Fasting State ◽  
Postprandial State

Elevated concentrations of fasting and non-fasting triacylglycerol-rich lipoproteins (TRL) as well as oxidative changes of lipoproteins may increase the risk of ischaemic heart disease. To compare the effects of different diets rich in unsaturated fatty acids on the concentrations andin vitrooxidation of fasting and postprandial lipoproteins eighteen males consumed diets enriched with rapeseed oil (RO), olive oil (OO), or sunflower-seed oil (SO) in randomised order for periods of 3 weeks followed by a RO test meal. In the postprandial state the concentrations of cholesterol and triacylglycerol (TAG) in TRL were higher after consumption of OO compared with RO and SO (P<0·04), possibly related to differences in the fasting state. The propagation rates for VLDL and LDL oxidation were higher in the postprandial compared with the fasting state irrespective of diet. In the fasting state, the propagation rates were highest after SO (P<0·001), and in the postprandial state, SO gave rise to a shorter VLDL lag time (P=0·03) and a higher propagation rate than OO consumption (P=0·04). Overall, the SO diet resulted in a higher postprandial propagation rate of LDL (P<0·001) compared with RO and OO, while there was no effect of diet on LDL oxidation lag time. Our results suggest that RO and SO diets lower the postprandial cholesterol and TAG concentrations compared with OO, while RO and OO diets result in similar and lowerin vitrosusceptibility to oxidation of lipoproteins than SO.

Improved Measurement of Low-Density-Lipoprotein Susceptibility to Copper-Induced Oxidation: Application of a Short Procedure for Isolating Low-Density Lipoprotein

1992 ◽  
Vol 38 (10) ◽  
pp. 2066-2072 ◽  
Author(s):  
H A Kleinveld ◽  
H L Hak-Lemmers ◽  
A F Stalenhoef ◽  
P N Demacker
Keyword(s):  
Low Density Lipoprotein ◽  
Atherosclerotic Lesion ◽  
Density Lipoprotein ◽  
Thiobarbituric Acid ◽  
Lag Time ◽  
Butylated Hydroxytoluene ◽  
Ldl Oxidation ◽  
Low Density ◽  
Short Run

Abstract Low-density-lipoprotein (LDL) oxidation may provide the crucial link between plasma LDL and atherosclerotic-lesion formation. Oxidation can be induced in vitro by incubating LDL with cells or metal ions and can be measured by continuously monitoring conjugated-diene absorbance at 234 nm. Measurement of LDL oxidizability was improved by performing the assay with 0.05 g of LDL-protein per liter of phosphate buffer containing 1 mumol of EDTA, by initiating oxidation by adding CuCl2 (5 mumol/L) at 30 degrees C, and by using a short-run ultracentrifugation method for isolating LDL, which reduced the time needed for obtaining purified LDL and thus reduced in vitro oxidation. LDL apolipoprotein analysis and oxidizability determination showed that this method is better than the longer sequential-isolation procedure. Adding butylated hydroxytoluene (BHT) to plasma as an antioxidant unpredictably increased the LDL oxidation lag time, making BHT unsuitable as an antioxidant. Adding EDTA appeared to be sufficient to prevent in vitro oxidation. Additionally, the diene production correlated highly with the concentration of thiobarbituric acid-reactive substances (r = 0.97). No relation between the vitamin E content of LDL and the oxidation lag time was found.

Absorption and distribution of [l-14C]dolichol intubated into rats

1987 ◽  
Vol 65 (4) ◽  
pp. 317-320 ◽  
Author(s):  
Dean C. Crick ◽  
Kenneth K. Carroll
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Sunflower Seed ◽  
Seed Oil ◽  
High Density ◽  
High Density Lipoproteins ◽  
Sunflower Seed Oil ◽  
Layer Chromatography

[1-l4C]Dolichol was mixed in vitro with sunflower seed oil and intubated into rats. Radioactivity began to appear in the blood at 3 h and peaked after about 6 h. The absorbed radioactivity was rapidly cleared from the blood. At 7.5 h postintubation two thirds of the radioactivity in the serum was associated with chylomicrons and about one quarter with the high density lipoproteins. At 12 h the proportion of the radioactivity in the chylomicrons had fallen to one third and that in the high density lipoproteins had increased to one half of the total. Less than 0.02% of the dose was found in the tissues after 12 h. Liver and blood each contained about one third of the total, with smaller amounts in the lungs and spleen. The heart, testes, brain, and kidneys contained only traces of radioactivity. After 12 h most of the radioactivity in the tissues and feces was present as [1-l4C]dolichol. The radioactive compounds in the urine (about 0.05% of the dose) were more polar than [1-l4C]dolichol as determined by thin-layer chromatography.

scholarly journals Adaptation of biliary response to dietary olive oil and sunflower-seed oil in dogs

1992 ◽  
Vol 68 (1) ◽  
pp. 175-182 ◽  
Author(s):  
M. C. Ballesta ◽  
M. Mañas ◽  
E. Martinez-Victoria ◽  
I. Seiquer ◽  
J. R. Huertas ◽  
...  
Keyword(s):  
Food Intake ◽  
Olive Oil ◽  
Bile Acids ◽  
Dietary Fat ◽  
Sunflower Seed ◽  
Seed Oil ◽  
Food Concentration ◽  
Bile Secretion ◽  
Biliary Cholesterol ◽  
Sunflower Seed Oil

The effects of adaptation to dietary fat of different degrees of unsaturation (olive oil and sunflower oil) on bile secretion were studied in dogs at rest and after food intake. The animals were prepared with a bidirectional biliary cannula and a duodenal cannula to provide bile return. The two experimental groups were fed on diets containing 150 g fat/kg in the form of either olive oil (O) or sunflower-seed oil (S). The flow-rate under resting conditions and the patterns of response to food were similar in both experimental groups, although postprandial hypersection were significantly greater in volume and more prolonged in group O. No appreciable differences in concentration and output of biliary cholesterol or phospholipids were noted between the two groups. In contrast, the concentration and output of bile acids differed significantly both at rest and after food: concentration and output of bile acids were greater at rest in group S. However, after food intake, these responses were increased only in group O. The results suggest that the type of dietary fat affects biliary response to food, probably through differences in the contribution of the gall bladder in the two experimental groups.

A New Formulation Based on Ozonated Sunflower Seed Oil: In Vitro Antibacterial and Safety Evaluation

2017 ◽  
Vol 39 (3) ◽  
pp. 139-147 ◽  
Author(s):  
Francesca Serio ◽  
Graziano Pizzolante ◽  
Giuseppe Cozzolino ◽  
Maria D’Alba ◽  
Francesco Bagordo ◽  
...  
Keyword(s):  
Sunflower Seed ◽  
Seed Oil ◽  
Safety Evaluation ◽  
Sunflower Seed Oil ◽  
New Formulation
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