Urinary Fatty Acid Composition and Biomarkers Discovery for Type 2 Diabetic Patients Based on Ultra-Performance Liquid Chromatography-Quadrupole/Time of Flight Mass Spectrometry and Multivariate Statistical Analysis

2012 ◽  
Vol 45 (18) ◽  
pp. 2649-2662
Author(s):  
Wenjuan Xu ◽  
Liangxiao Zhang ◽  
Yuhong Huang ◽  
Qianxu Yang ◽  
Hongbin Xiao ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Fatty Acid Composition ◽  
Liquid Chromatography ◽  
Ultra Performance Liquid Chromatography ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Multivariate Statistical ◽  
Flight Mass Spectrometry ◽  
Type 2 Diabetic

Fatty Acid Composition of Serum Lipid Fractions in Type 2 Diabetic Patients With Microalbuminuria

Diabetes Care ◽  
2003 ◽  
Vol 26 (3) ◽  
pp. 613-618 ◽  
Author(s):  
M. S. Perassolo ◽  
J. C. Almeida ◽  
R. L. Pra ◽  
V. D. Mello ◽  
A. L. Maia ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Serum Lipid ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Lipid Fractions ◽  
Type 2 Diabetic

Effects of soybean D-LeciVita product on serum lipids and fatty acid composition in type 2 diabetic patients with hyperlipidemia

2006 ◽  
Vol 16 (6) ◽  
pp. 395-404 ◽  
Author(s):  
Danijela Ristić Medić ◽  
Vanja Ristić ◽  
Aleksandra Arsić ◽  
Marija Poštić ◽  
Gordana Ristić ◽  
...  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Acid Composition ◽  
Serum Lipids ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

scholarly journals Comparative Analysis of Chemical Constituents of Moringa oleifera Leaves from China and India by Ultra-Performance Liquid Chromatography Coupled with Quadrupole-Time-Of-Flight Mass Spectrometry

Molecules ◽  
2019 ◽  
Vol 24 (5) ◽  
pp. 942 ◽  
Author(s):  
Hongqiang Lin ◽  
Hailin Zhu ◽  
Jing Tan ◽  
Han Wang ◽  
Zhongyao Wang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Moringa Oleifera ◽  
Chemical Constituents ◽  
Time Of Flight ◽  
Ultra Performance Liquid Chromatography ◽  
Multivariate Statistical ◽  
Flight Mass Spectrometry ◽  
Moringa Oleifera Leaves ◽  
Potential Biomarkers

With the aim to discuss the similarities and differences of phytochemicals in Moringa oleifera leaves collected from China (CML) and India (IML) in mind, comparative ultra-performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry (UPLC-QTOF-MS) analysis was performed in this study. A screening analysis based on a UNIFI platform was first carried out to discuss the similarities. Next, untargeted metabolomic analysis based on multivariate statistical analysis was performed to discover the differences. As a result, a total of 122 components, containing 118 shared constituents, were characterized from CML and IML. The structure types included flavonoids, alkaloids, glyosides, organic acids and organic acid esters, iridoids, lignans, and steroids, etc. For CML, 121 compounds were characterized; among these, 18 potential biomarkers with higher contents enabled differentiation from IML. For IML, 119 compounds were characterized; among these, 12 potential biomarkers with higher contents enabled differentiation from CML. It could be concluded that both CML and IML are rich in phytochemicals and that CML is similar to IML in the kinds of the compounds it contains, except for the significant differences in the contents of some compounds. This comprehensive phytochemical profile study provides a basis for explaining the effect of different growth environments on secondary metabolites and exists as a reference for further research into or applications of CML in China.

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