Evaluation of Elastomers for Biomedical Applications Utilizingin vivoandin vitroModel Systems—State of the Art and Future Trends

In the past two decades, COMSOL Multiphysics Software Package have emerged as a powerful tool for simulation, particularly in Nanotechnology and most importantly in biomedical application and various application involving fluid and solid interactions. Compared with conventional component or system design, distinctive advantages of using COMSOL software for design include easy assessing to the significant parameters in various levels of design, higher throughput, process monitoring with lower cost and less time consuming [1,. This review aims to summarize the recent advancements in various approaches in major types of micro fluidic systems simulations, design application of various COMSOL models especially in biomedical applications. The state-of-the-art of past and current approaches of fluid manipulation as well as solid structure design fabrication was also elaborated. Future trends of using COMSOL in nanotechnology, especially in biomedical engineering perspective.

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PET Radiochemistry Automation: State of the Art and Future Trends in 18F-nucleophilic Fluorination

Current Organic Chemistry ◽

10.2174/13852728113179990102 ◽

2013 ◽

Vol 17 (19) ◽

pp. 2097-2107 ◽

Cited By ~ 18

Author(s):

Raisa Krasikova

Keyword(s):

State Of The Art ◽

Future Trends ◽

Nucleophilic Fluorination

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Application of Microextraction-Based Techniques for Screening-Controlled Drugs in Forensic Context—A Review

Molecules ◽

10.3390/molecules26082168 ◽

2021 ◽

Vol 26 (8) ◽

pp. 2168

Author(s):

Samir M. Ahmad ◽

Oriana C. Gonçalves ◽

Mariana N. Oliveira ◽

Nuno R. Neng ◽

José M. F. Nogueira

Keyword(s):

Environmental Sustainability ◽

Illicit Drugs ◽

State Of The Art ◽

Cost Benefit ◽

Future Trends ◽

Present Contribution ◽

Controlled Drugs ◽

Related Compounds ◽

Innovative Techniques ◽

Great Simplicity

The analysis of controlled drugs in forensic matrices, i.e., urine, blood, plasma, saliva, and hair, is one of the current hot topics in the clinical and toxicological context. The use of microextraction-based approaches has gained considerable notoriety, mainly due to the great simplicity, cost-benefit, and environmental sustainability. For this reason, the application of these innovative techniques has become more relevant than ever in programs for monitoring priority substances such as the main illicit drugs, e.g., opioids, stimulants, cannabinoids, hallucinogens, dissociative drugs, and related compounds. The present contribution aims to make a comprehensive review on the state-of-the art advantages and future trends on the application of microextraction-based techniques for screening-controlled drugs in the forensic context.

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Challenges in the Fabrication of Biodegradable and Implantable Optical Fibers for Biomedical Applications

Materials ◽

10.3390/ma14081972 ◽

2021 ◽

Vol 14 (8) ◽

pp. 1972

Author(s):

Agnieszka Gierej ◽

Thomas Geernaert ◽

Sandra Van Vlierberghe ◽

Peter Dubruel ◽

Hugo Thienpont ◽

...

Keyword(s):

Systematic Review ◽

Optical Fibers ◽

Optical Waveguides ◽

Biomedical Applications ◽

State Of The Art ◽

Chemical Properties ◽

Biological Tissues ◽

Biodegradable Materials ◽

Essential Properties ◽

Optically Transparent

The limited penetration depth of visible light in biological tissues has encouraged researchers to develop novel implantable light-guiding devices. Optical fibers and waveguides that are made from biocompatible and biodegradable materials offer a straightforward but effective approach to overcome this issue. In the last decade, various optically transparent biomaterials, as well as different fabrication techniques, have been investigated for this purpose, and in view of obtaining fully fledged optical fibers. This article reviews the state-of-the-art in the development of biocompatible and biodegradable optical fibers. Whilst several reviews that focus on the chemical properties of the biomaterials from which these optical waveguides can be made have been published, a systematic review about the actual optical fibers made from these materials and the different fabrication processes is not available yet. This prompted us to investigate the essential properties of these biomaterials, in view of fabricating optical fibers, and in particular to look into the issues related to fabrication techniques, and also to discuss the challenges in the use and operation of these optical fibers. We close our review with a summary and an outline of the applications that may benefit from these novel optical waveguides.

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