COMSOL Multiphysics Simulation in Biomedical Engineering

2013 ◽  
Vol 832 ◽  
pp. 511-516 ◽  
Author(s):  
Tijjani Adam ◽  
U. Hashim
Keyword(s):  
Biomedical Engineering ◽  
Biomedical Applications ◽  
Lower Cost ◽  
State Of The Art ◽  
Biomedical Application ◽  
Structure Design ◽  
Comsol Multiphysics ◽  
Future Trends ◽  
The Past ◽  
Fluid Manipulation

In the past two decades, COMSOL Multiphysics Software Package have emerged as a powerful tool for simulation, particularly in Nanotechnology and most importantly in biomedical application and various application involving fluid and solid interactions. Compared with conventional component or system design, distinctive advantages of using COMSOL software for design include easy assessing to the significant parameters in various levels of design, higher throughput, process monitoring with lower cost and less time consuming [1,. This review aims to summarize the recent advancements in various approaches in major types of micro fluidic systems simulations, design application of various COMSOL models especially in biomedical applications. The state-of-the-art of past and current approaches of fluid manipulation as well as solid structure design fabrication was also elaborated. Future trends of using COMSOL in nanotechnology, especially in biomedical engineering perspective.

scholarly journals Recent Advances in Zwitterionic Hydrogels: Preparation, Property, and Biomedical Application

Gels ◽  
2022 ◽  
Vol 8 (1) ◽  
pp. 46
Author(s):  
Sihang Liu ◽  
Jingyi Tang ◽  
Fangqin Ji ◽  
Weifeng Lin ◽  
Shengfu Chen
Keyword(s):  
Immune System ◽  
Polyethylene Glycol ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Synthetic Polymers ◽  
Human Environment ◽  
The Past ◽  
Recent Advances ◽  
Nonspecific Protein Adsorption ◽  
Anionic Groups

Nonspecific protein adsorption impedes the sustainability of materials in biologically related applications. Such adsorption activates the immune system by quick identification of allogeneic materials and triggers a rejection, resulting in the rapid failure of implant materials and drugs. Antifouling materials have been rapidly developed in the past 20 years, from natural polysaccharides (such as dextran) to synthetic polymers (such as polyethylene glycol, PEG). However, recent studies have shown that traditional antifouling materials, including PEG, still fail to overcome the challenges of a complex human environment. Zwitterionic materials are a class of materials that contain both cationic and anionic groups, with their overall charge being neutral. Compared with PEG materials, zwitterionic materials have much stronger hydration, which is considered the most important factor for antifouling. Among zwitterionic materials, zwitterionic hydrogels have excellent structural stability and controllable regulation capabilities for various biomedical scenarios. Here, we first describe the mechanism and structure of zwitterionic materials. Following the preparation and property of zwitterionic hydrogels, recent advances in zwitterionic hydrogels in various biomedical applications are reviewed.

Reconstructing the Past

2018 ◽  
pp. 140-172
Author(s):  
Luís G. Magalhães ◽  
Telmo Adão ◽  
Emanuel Peres
Keyword(s):  
State Of The Art ◽  
Archaeological Site ◽  
The State ◽  
Archaeological Sites ◽  
Future Trends ◽  
Virtual Model ◽  
Entire Process ◽  
The Past ◽  
Virtual Reconstruction ◽  
Methods And Techniques

Accurate modeling/reconstruction and visualization of real environments, particularly archaeological sites, is both a major challenge and a crucial task. This work will address the entire process of the virtual reconstruction of archaeological sites, since the construction of the virtual model until its visualization. The chapter begins with an introduction to the process of virtual reconstruction of archaeological sites, where the several stages that should take place to obtain a faithful virtual representation of an archaeological site and its artifacts are identified. Moreover, each stage is characterized and its main methods and techniques are identified, in dedicated sections. The authors' contribution for the state of the art will be highlighted in each stage. The chapter ends with the authors' vision about future trends for this field and unveils what could be their contributions to this vision.

Recent Research on Flavonoids and their Biomedical applications

2020 ◽  
Vol 27 ◽  
Author(s):  
Kui Cheng ◽  
Kangmei Wang ◽  
Xiaochuan Fang ◽  
Junli Yang ◽  
Yongfang Yao ◽  
...  
Keyword(s):  
Phenolic Compounds ◽  
Biomedical Applications ◽  
Structural Unit ◽  
Biomedical Application ◽  
Cardiovascular Complications ◽  
Mechanisms Of Action ◽  
Biological Applications ◽  
Pharmacological Activities ◽  
The Past ◽  
Health Disorders

: Flavonoids, commonly found in various plants, are a class of poly-phenolic compounds having a basic structural unit of 2-phenylchromone. Flavonoid compounds have attracted much attention due to their wide biological applications. In order to facilitate further research on biomedical application of flavonoids, we surveyed the literature published on the use of flavonoids in medicine during the past decade, documented the commonly found structures in natural flavonoids, and summarized their pharmacological activities as well as associated mechanisms of action against variety of health disorders including chronic inflammation, cancer, cardiovascular complications and hypoglycemia. In this mini-review, we provide suggestions for further research on the biomedical applications of flavonoids.

Virtual Fabrication Technology Weld Modeling Tool and Its Applications in Distortion Predictions

2003 ◽  
Author(s):  
Y. P. Yang ◽  
F. W. Brust ◽  
Z. Cao
Keyword(s):  
Predictive Power ◽  
State Of The Art ◽  
Structure Design ◽  
Simulation Tool ◽  
Fabrication Technology ◽  
Complicated Structure ◽  
Fabrication Cost ◽  
The Past ◽  
Welded Structure ◽  
Design And Manufacture

A virtual fabrication technology (VFT) is introduced in this paper. It is a state-of-the-art cutting and welding simulation tool developed by Battelle and Caterpillar in the past few years. It can model extremely large and complicated structure fabrications. Extensive full-scale experiments have validated the accuracy and predictive power. It can be used to reduce fabrication cost and improve quality by minimizing and controlling distortions. Two application examples are presented to illustrate how to apply this tool in welded structure design and manufacture.

scholarly journals Advanced Nanomaterials in Multimodal Imaging: Design, Functionalization, and Biomedical Applications

2010 ◽  
Vol 2010 ◽  
pp. 1-15 ◽  
Author(s):  
Zhe Liu ◽  
Fabian Kiessling ◽  
Jessica Gätjens
Keyword(s):  
Drug Delivery ◽  
Molecular Imaging ◽  
Contrast Agents ◽  
Multimodal Imaging ◽  
Biomedical Applications ◽  
State Of The Art ◽  
The Past ◽  
Recent Advances ◽  
Imaging Probes ◽  
New Generation

The biomedical applications of nanoparticles in molecular imaging, drug delivery, and therapy give rise to the term “nanomedicine” and have led to ever-growing developments in the past decades. New generation of imaging probes (or contrast agents) and state of the art of various strategies for efficient multimodal molecular imaging have drawn much attention and led to successful preclinical uses. In this context, we intend to elucidate the fundamentals and review recent advances as well as to provide an outlook perspective in these fields.

Guided Weapon Simulators

1968 ◽  
Vol 72 (688) ◽  
pp. 356-360
Author(s):  
I. N. Cartmell ◽  
R. W. Williams
Keyword(s):  
State Of The Art ◽  
Past History ◽  
Original System ◽  
Future Trends ◽  
Paper Briefly ◽  
Joint Paper ◽  
The Past ◽  
History Of ◽  
The Subject ◽  
Model Technique

The authors were requested to present short papers giving opposing views on the subject of Guided Weapon Simulators. Much of this subject is now a matter of fact and the authors found themselves in agreement on far too many points regarding the present situation to follow the requested approach, and instead have adopted the method of writing a joint paper briefly reviewing the past history of simulation and setting out the present state of the art as they see it, leaving the discussion of probable future trends to encourage controversy. It has still been difficult to be controversial, but if some of the statements made stimulate discussion then a useful purpose will have been served. It may turn out that what the authors have found difficult to produce between themselves has been created only too readily between themselves and their audience. It is not possible to discuss simulators without bringing in the concept of modelling, indeed an apt title for this paper could have been “From Simulation to Modelling”. The model technique has been defined as “a procedure in which a representation of a system is developed in some more convenient medium and checked to show that its behaviour agrees with that of the original system for a wide variety of conditions”.

How SIMS microscopy can be used in medicine

1992 ◽  
Vol 50 (2) ◽  
pp. 1602-1603
Author(s):  
Philippe Fragu
Keyword(s):  
Mass Spectrometry ◽  
Biomedical Applications ◽  
Secondary Ion Mass Spectrometry ◽  
Chemical Elements ◽  
Biological Applications ◽  
The Past ◽  
Potential Source ◽  
Secondary Ion ◽  
Chemical Integrity ◽  
Scientific Endeavour

The identification, localization and quantification of intracellular chemical elements is an area of scientific endeavour which has not ceased to develop over the past 30 years. Secondary Ion Mass Spectrometry (SIMS) microscopy is widely used for elemental localization problems in geochemistry, metallurgy and electronics. Although the first commercial instruments were available in 1968, biological applications have been gradual as investigators have systematically examined the potential source of artefacts inherent in the method and sought to develop strategies for the analysis of soft biological material with a lateral resolution equivalent to that of the light microscope. In 1992, the prospects offered by this technique are even more encouraging as prototypes of new ion probes appear capable of achieving the ultimate goal, namely the quantitative analysis of micron and submicron regions. The purpose of this review is to underline the requirements for biomedical applications of SIMS microscopy.Sample preparation methodology should preserve both the structural and the chemical integrity of the tissue.

A Macintosh Interface for the Cameca Camebax-Micro Electron Microprobe

1990 ◽  
Vol 48 (1) ◽  
pp. 438-439
Author(s):  
Carl E. Henderson
Keyword(s):  
Electron Microprobe ◽  
Processing Speed ◽  
Word Processing ◽  
State Of The Art ◽  
Computer Control ◽  
Third Party ◽  
Disk Storage ◽  
The Past ◽  
User Facility ◽  
Instrument Control

Over the past few years it has become apparent in our multi-user facility that the computer system and software supplied in 1985 with our CAMECA CAMEBAX-MICRO electron microprobe analyzer has the greatest potential for improvement and updating of any component of the instrument. While the standard CAMECA software running on a DEC PDP-11/23+ computer under the RSX-11M operating system can perform almost any task required of the instrument, the commands are not always intuitive and can be difficult to remember for the casual user (of which our laboratory has many). Given the widespread and growing use of other microcomputers (such as PC’s and Macintoshes) by users of the microprobe, the PDP has become the “oddball” and has also fallen behind the state-of-the-art in terms of processing speed and disk storage capabilities. Upgrade paths within products available from DEC are considered to be too expensive for the benefits received. After using a Macintosh for other tasks in the laboratory, such as instrument use and billing records, word processing, and graphics display, its unique and “friendly” user interface suggested an easier-to-use system for computer control of the electron microprobe automation. Specifically a Macintosh IIx was chosen for its capacity for third-party add-on cards used in instrument control.

Graphene and Graphene-Based Materials in Biomedical Applications

2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic
Keyword(s):  
Tissue Engineering ◽  
Thermal Properties ◽  
Gene Delivery ◽  
Regenerative Medicine ◽  
Biomedical Research ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Two Dimensional ◽  
Drug And Gene Delivery ◽  
Biomedical Fields

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.

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