Converging 2D Nanomaterials and 3D Bioprinting Technology: State‐of‐the‐Art, Challenges, and Potential Outlook in Biomedical Applications (Adv. Healthcare Mater. 22/2021)

The limited penetration depth of visible light in biological tissues has encouraged researchers to develop novel implantable light-guiding devices. Optical fibers and waveguides that are made from biocompatible and biodegradable materials offer a straightforward but effective approach to overcome this issue. In the last decade, various optically transparent biomaterials, as well as different fabrication techniques, have been investigated for this purpose, and in view of obtaining fully fledged optical fibers. This article reviews the state-of-the-art in the development of biocompatible and biodegradable optical fibers. Whilst several reviews that focus on the chemical properties of the biomaterials from which these optical waveguides can be made have been published, a systematic review about the actual optical fibers made from these materials and the different fabrication processes is not available yet. This prompted us to investigate the essential properties of these biomaterials, in view of fabricating optical fibers, and in particular to look into the issues related to fabrication techniques, and also to discuss the challenges in the use and operation of these optical fibers. We close our review with a summary and an outline of the applications that may benefit from these novel optical waveguides.

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Hydrogel-Based Bioinks for Three-Dimensional Bioprinting: Patent Analysis

Materials Proceedings ◽

10.3390/iocps2021-11239 ◽

2021 ◽

Vol 7 (1) ◽

pp. 3

Author(s):

Ahmed Fatimi

Keyword(s):

Tissue Engineering ◽

Detailed Analysis ◽

State Of The Art ◽

Three Dimensional ◽

Patent Analysis ◽

The State ◽

Driving Factors ◽

3D Bioprinting ◽

Preparation Methods

There are a variety of hydrogel-based bioinks commonly used in three-dimensional bioprinting. In this study, in the form of patent analysis, the state of the art has been reviewed by introducing what has been patented in relation to hydrogel-based bioinks. Furthermore, a detailed analysis of the patentability of the used hydrogels, their preparation methods and their formulations, as well as the 3D bioprinting process using hydrogels, have been provided by determining publication years, jurisdictions, inventors, applicants, owners, and classifications. The classification of patents reveals that most inventions intended for hydrogels used as materials for prostheses or for coating prostheses are characterized by their function or properties Knowledge clusters and expert driving factors show that biomaterials, tissue engineering, and biofabrication research is concentrated in the most patents.

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Plant-Derived Biomaterials: A Review of 3D Bioprinting and Biomedical Applications

Frontiers in Mechanical Engineering ◽

10.3389/fmech.2019.00019 ◽

2019 ◽

Vol 5 ◽

Cited By ~ 25

Author(s):

Thomas H. Jovic ◽

Garikai Kungwengwe ◽

Adam C. Mills ◽

Iain S. Whitaker

Keyword(s):

Biomedical Applications ◽

3D Bioprinting

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Recent Advances in Bioplastics: Application and Biodegradation

Polymers ◽

10.3390/polym12040920 ◽

2020 ◽

Vol 12 (4) ◽

pp. 920 ◽

Cited By ~ 8

Author(s):

Tanja Narancic ◽

Federico Cerrone ◽

Niall Beagan ◽

Kevin E. O’Connor

Keyword(s):

Biodegradable Polymers ◽

Biomedical Applications ◽

Drug Delivery Systems ◽

State Of The Art ◽

Weight Ratio ◽

Challenges And Opportunities ◽

Single Use ◽

Art Research ◽

Degradation Properties ◽

Design And Application

The success of oil-based plastics and the continued growth of production and utilisation can be attributed to their cost, durability, strength to weight ratio, and eight contributions to the ease of everyday life. However, their mainly single use, durability and recalcitrant nature have led to a substantial increase of plastics as a fraction of municipal solid waste. The need to substitute single use products that are not easy to collect has inspired a lot of research towards finding sustainable replacements for oil-based plastics. In addition, specific physicochemical, biological, and degradation properties of biodegradable polymers have made them attractive materials for biomedical applications. This review summarises the advances in drug delivery systems, specifically design of nanoparticles based on the biodegradable polymers. We also discuss the research performed in the area of biophotonics and challenges and opportunities brought by the design and application of biodegradable polymers in tissue engineering. We then discuss state-of-the-art research in the design and application of biodegradable polymers in packaging and emphasise the advances in smart packaging development. Finally, we provide an overview of the biodegradation of these polymers and composites in managed and unmanaged environments.

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Biomedical applications of nanobiosensors: the state-of-the-art

Journal of the Brazilian Chemical Society ◽

10.1590/s0103-50532012000100004 ◽

2012 ◽

Cited By ~ 5

Author(s):

Mahendra Rai ◽

Aniket Gade ◽

Swapnil Gaikwad ◽

Priscyla D. Marcato ◽

Nelson Durán

Keyword(s):

Biomedical Applications ◽

State Of The Art ◽

The State

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Fused deposition modelling based rapid patterns for investment casting applications: a review

Rapid Prototyping Journal ◽

10.1108/rpj-02-2014-0017 ◽

2016 ◽

Vol 22 (1) ◽

pp. 123-143 ◽

Cited By ~ 19

Author(s):

Sunpreet Singh ◽

Rupinder Singh

Keyword(s):

Investment Casting ◽

Biomedical Applications ◽

Design Methodology ◽

State Of The Art ◽

Fused Deposition Modelling ◽

Content Type ◽

Biomedical Implant ◽

Fused Deposition ◽

Manufacturing Organizations ◽

Machine Parts

Purpose – This paper aims to review the industrial and biomedical applications of state-of-the-art fused deposition modelling (FDM)-assisted investment casting (FDMAIC). Brief literature survey of methodologies, ideas, techniques and approaches used by various researchers is highlighted and use of hybrid feedstock filament-based pattern to produce metal matrix composite is duly discussed. Design/methodology/approach – Pattern replica required for investment casting (IC) of biomedical implant, machine parts, dentistry and other industrial components can be directly produced by using FDM process is presented. Relevant studies and examples explaining the suitability of FDMAIC for various applications are also presented. Findings – Researches to optimize the conventional IC with FDM solutions and develop new hybrid feedstock filament of FDM done by researchers worldwide are also discussed. The review highlights the benefit of FDMAIC to surgeons, engineers and manufacturing organizations. Research limitations/implications – The research related to this survey is limited to the suitability and applicability of FDMAIC. Originality/value – This review presents the information regarding potential IC application, which facilitates the society, engineers and manufacturing organizations by providing variety of components for assisting FDM. The information reported in this paper will serve doctors, researchers, organizations and academicians to explore the new options in the field of FDMAIC.

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Recent Advances of Gold Nanoparticles in Biomedical Applications: State of the Art

Cell Biochemistry and Biophysics ◽

10.1007/s12013-018-0863-4 ◽

2018 ◽

Vol 77 (2) ◽

pp. 123-137 ◽

Cited By ~ 25

Author(s):

Negar Sedghi Aminabad ◽

Masoud Farshbaf ◽

Abolfazl Akbarzadeh

Keyword(s):

Gold Nanoparticles ◽

Biomedical Applications ◽

State Of The Art ◽

Recent Advances

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A Guideline for Effectively Synthesizing and Characterizing Magnetic Nanoparticles for Advancing Nanobiotechnology: A Review

Sensors ◽

10.3390/s20092554 ◽

2020 ◽

Vol 20 (9) ◽

pp. 2554 ◽

Cited By ~ 4

Author(s):

Mohammad Reza Zamani Kouhpanji ◽

Bethanie J. H. Stadler

Keyword(s):

Magnetic Nanoparticles ◽

Biomedical Applications ◽

State Of The Art ◽

Future Directions ◽

Current State ◽

Pros And Cons ◽

Synthesis Routes ◽

Size And Morphology ◽

Excellent Source ◽

Source Of Information

The remarkable multimodal functionalities of magnetic nanoparticles, conferred by their size and morphology, are very important in resolving challenges slowing the progression of nanobiotechnology. The rapid and revolutionary expansion of magnetic nanoparticles in nanobiotechnology, especially in nanomedicine and therapeutics, demands an overview of the current state of the art for synthesizing and characterizing magnetic nanoparticles. In this review, we explain the synthesis routes for tailoring the size, morphology, composition, and magnetic properties of the magnetic nanoparticles. The pros and cons of the most popularly used characterization techniques for determining the aforementioned parameters, with particular focus on nanomedicine and biosensing applications, are discussed. Moreover, we provide numerous biomedical applications and highlight their challenges and requirements that must be met using the magnetic nanoparticles to achieve the most effective outcomes. Finally, we conclude this review by providing an insight towards resolving the persisting challenges and the future directions. This review should be an excellent source of information for beginners in this field who are looking for a groundbreaking start but they have been overwhelmed by the volume of literature.

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