Antiproliferative Effects of Thymoquinone in MCF-7 Breast and HepG2 Liver Cancer Cells: Possible Role of Ceramide and ER Stress

2020 ◽  
pp. 1-13
Author(s):  
Mutay Aslan ◽  
Ebru Afşar ◽  
Esma Kırımlıoglu ◽  
Tuğçe Çeker ◽  
Çağatay Yılmaz
Keyword(s):  
Liver Cancer ◽  
Er Stress ◽  
Cancer Cells ◽  
Antiproliferative Effects ◽  
Liver Cancer Cells ◽  
Mcf 7

Relevance of mitochondrial dysfunction during Sorafenib-induced cell death in liver cancer cells. Role of oxidative and nitrogen reactive species

2021 ◽  
Vol 165 ◽  
pp. 54
Author(s):  
Patricia de la Cruz-Ojeda ◽  
M. Ángeles Rodríguez-Hernández ◽  
Elena Navarro-Villarán ◽  
Paloma Gallego ◽  
Pavla Staňková ◽  
...  
Keyword(s):  
Cell Death ◽  
Liver Cancer ◽  
Mitochondrial Dysfunction ◽  
Cancer Cells ◽  
Reactive Species ◽  
Liver Cancer Cells ◽  
Nitrogen Reactive Species

scholarly journals A critical role of AMPK, and Akt, mTOR and Wnt survival signals for the growth control of colon and liver cancer cells with selenium

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Lee Yun‐Kyoung ◽  
Song Yi Park ◽  
Won Sup Lee ◽  
Young‐Joon Surh ◽  
Young‐Min Kim ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
Critical Role ◽  
Growth Control ◽  
Liver Cancer Cells ◽  
Survival Signals

scholarly journals The Role of Exosomes in the Crosstalk between Adipocytes and Liver Cancer Cells

Cells ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 1988
Author(s):  
Leslimar Rios-Colon ◽  
Elena Arthur ◽  
Suryakant Niture ◽  
Qi Qi ◽  
John T. Moore ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
Bioactive Materials ◽  
Liver Cancer Cells ◽  
Secreted Factors ◽  
Wide Range ◽  
Pathophysiological Role ◽  
Inflammatory State ◽  
Membrane Bound

Exosomes are membrane-bound extracellular vesicles (EVs) that transport bioactive materials between cells and organs. The cargo delivered by exosomes can alter a wide range of cellular responses in recipient cells and play an important pathophysiological role in human cancers. In hepatocellular carcinoma (HCC), for example, adipocyte- and tumor-secreted factors contained in exosomes contribute to the creation of a chronic inflammatory state, which contributes to disease progression. The exosome-mediated crosstalk between adipocytes and liver cancer cells is a key aspect of a dynamic tumor microenvironment. In this review, we summarize the role of increased adiposity and the role of adipocyte-derived exosomes (AdExos) and HCC-derived exosomes (HCCExos) in the modulation of HCC progression. We also discuss recent advances regarding how malignant cells interact with the surrounding adipose tissue and employ exosomes to promote a more aggressive phenotype.

Role of IL‐6‐mediated expression of NS5ATP9 in autophagy of liver cancer cells

2018 ◽  
Vol 233 (12) ◽  
pp. 9312-9319 ◽  
Author(s):  
Hongping Lu ◽  
Ming Han ◽  
Xiaoxue Yuan ◽  
Kelbinur Tursun ◽  
Yu Zhang ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
Liver Cancer Cells

scholarly journals Role of the cystathionine β-synthase/H2S system in liver cancer cells and the inhibitory effect of quinolone-indolone conjugate QIC2 on the system

2017 ◽  
Vol 37 (5) ◽  
pp. 3001-3009 ◽  
Author(s):  
Huina Jia ◽  
Juan Ye ◽  
Jing You ◽  
Xiaoyan Shi ◽  
Wenyi Kang ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Cells ◽  
Inhibitory Effect ◽  
Liver Cancer Cells
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