Lifestyle changes and risk of cancer: experience from the Swedish women's lifestyle and health cohort study

2021 ◽  
pp. 1-8
Author(s):  
Edoardo Botteri ◽  
Paula Berstad ◽  
Sven Sandin ◽  
Elisabete Weiderpass
Keyword(s):  
Cohort Study ◽  
Lifestyle Changes ◽  
Cancer Experience ◽  
Health Cohort Study ◽  
Risk Of Cancer

scholarly journals Lifestyle, psychological stress, and incidence of adolescent constipation: results from the Toyama birth cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Masaaki Yamada ◽  
Michikazu Sekine ◽  
Takashi Tatsuse ◽  
Yuko Fujimura
Keyword(s):  
Cohort Study ◽  
Prospective Study ◽  
Birth Cohort ◽  
Healthy Lifestyle ◽  
Lifestyle Changes ◽  
Psychological Status ◽  
Birth Cohort Study ◽  
Female Sex ◽  
Bowel Movement Frequency ◽  
Skipping Breakfast

Abstract Background We aimed to clarify the predisposing factors for adolescent constipation in a longitudinal study, because while factors associated with childhood constipation have been reported, prospective studies on the incidence of constipation are lacking. Methods We enrolled 5540 adolescents aged 12 to 13 years from the Toyama Birth Cohort Study—a community-based prospective study examining children’s health. The incidence of constipation, defined as bowel movement frequency of less than once every 2 days, was surveyed during the three-year period from baseline (grade 4) to follow-up (grade 7). Multivariate logistic regression analyses were performed to explore the association between the incidence of adolescent constipation and their lifestyle variables. Results A total of 261 adolescents (4.7%) developed constipation during the three-year period. Female sex (odds ratio [OR] = 2.62,) overweight (OR = 0.60), and infrequent intake of fruits (OR = 1.50) at baseline were associated with the incidence of constipation. Furthermore, factors related to lifestyle changes and psychological status such as skipping breakfast (OR = 1.73), becoming physically inactive (OR = 1.55), and being persistently irritated (OR = 1.80) were significantly associated with the incidence of constipation. Conclusion Our prospective study demonstrated that female sex, insufficient fruit intake, and deteriorating lifestyles such as skipping breakfast and becoming inactive during the 3-year period were associated with the incidence of adolescent constipation. Beyond anecdotal, maintaining a healthy lifestyle is recommended to reduce the incidence of adolescent constipation.

scholarly journals Risk of Cancer Following the Use of N-Nitrosodimethylamine (NDMA) Contaminated Ranitidine Products: A Nationwide Cohort Study in South Korea

2021 ◽  
Vol 10 (1) ◽  
pp. 153
Author(s):  
Hong Jin Yoon ◽  
Jie-Hyun Kim ◽  
Gi Hyeon Seo ◽  
Hyojin Park
Keyword(s):  
Cohort Study ◽  
Cancer Risk ◽  
South Korea ◽  
Primary Study ◽  
Study Cohort ◽  
Matched Cohort ◽  
Cancer Outcomes ◽  
H2 Receptor Antagonist ◽  
Carcinogenic Agent ◽  
Risk Of Cancer

N-nitrosodimethylamine (NDMA), a known carcinogenic agent, was recently detected in some products of ranitidine. Several studies have investigated the detectability of NDMA, in drugs and their risks. However, only a few epidemiological studies have evaluated cancer risk from the use of such individual drugs. This study investigates the risk of cancer in ranitidine users. We conducted an observational population-based cohort study using the Health Insurance Review and Assessment databases, which contain information about the use of medicines in South Korea. The primary study cohort consisted of ranitidine users (n = 88,416). For controls, we enrolled users of famotidine, another H2-receptor antagonist in which no NDMA has been detected. A 4:1 matched cohort was constructed to compare cancer outcomes of the two groups. Our matched cohort comprised of 40,488 ranitidine users and 10,122 famotidine users. There was no statistical difference in the overall cancer risk between the ranitidine and famotidine groups (7.45% vs. 7.56%, HR 0.99, 95% CI 0.91–1.07, p = 0.716). Additionally, no significant differences were observed in the analysis of 11 single cancer outcomes. We found no evidence that exposure to NDMA through ranitidine increases the risk of cancer.

Higher Plasma Amyloid-β Levels Are Associated with a Higher Risk of Cancer: A Population-Based Prospective Cohort Study

2020 ◽  
Vol 29 (10) ◽  
pp. 1993-2001
Author(s):  
Kimberly D. van der Willik ◽  
Mohsen Ghanbari ◽  
Lana Fani ◽  
Annette Compter ◽  
Rikje Ruiter ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Amyloid Β ◽  
Population Based ◽  
Risk Of Cancer

scholarly journals Increased risk of cancer in chronic dialysis patients: a population-based cohort study in Taiwan

2011 ◽  
Vol 27 (4) ◽  
pp. 1585-1590 ◽  
Author(s):  
H.-F. Lin ◽  
Y.-H. Li ◽  
C.-H. Wang ◽  
C.-L. Chou ◽  
D.-J. Kuo ◽  
...  
Keyword(s):  
Cohort Study ◽  
Population Based ◽  
Chronic Dialysis ◽  
Dialysis Patients ◽  
Increased Risk ◽  
Risk Of Cancer

scholarly journals Venous thromboembolism and subsequent risk of cancer in patients with liver disease: a population-based cohort study

2015 ◽  
Vol 2 (1) ◽  
pp. e000043 ◽  
Author(s):  
Jonathan Montomoli ◽  
Rune Erichsen ◽  
Kirstine Kobberøe Søgaard ◽  
Dóra Körmendiné Farkas ◽  
Anna-Marie Bloch Münster ◽  
...  
Keyword(s):  
Cohort Study ◽  
Liver Disease ◽  
Venous Thromboembolism ◽  
Population Based ◽  
Risk Of Cancer ◽  
Subsequent Risk

scholarly journals Suicide Attempt and Future Risk of Cancer—A Nationwide Cohort Study in Sweden.

2015 ◽  
Vol 44 (suppl_1) ◽  
pp. i11-i12
Author(s):  
R. Ljung ◽  
F. Mattsson ◽  
K. Lagergren ◽  
J. Jokinen ◽  
J. Lagergren
Keyword(s):  
Cohort Study ◽  
Suicide Attempt ◽  
Future Risk ◽  
Risk Of Cancer

scholarly journals Associations between maternal characteristics and pharmaceutical treatment of gestational diabetes: an analysis of the UK Born in Bradford (BiB) cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e053753
Author(s):  
Gilberte Martine-Edith ◽  
William Johnson ◽  
Eugenie Hunsicker ◽  
Mark Hamer ◽  
Emily S Petherick
Keyword(s):  
Cohort Study ◽  
Gestational Diabetes ◽  
Fasting Glucose ◽  
Lifestyle Changes ◽  
Relative Risk Ratio ◽  
Oral Glucose ◽  
Pharmaceutical Treatment ◽  
Maternal Characteristics ◽  
Born In Bradford ◽  
Treatment Type

ObjectivesTo identify the maternal characteristics associated with pharmaceutical treatment of gestational diabetes mellitus (GDM).DesignProspective birth cohort study.SettingBradford, UK.Participants762 women from the Born in Bradford (BiB) cohort who were treated for GDM in a singleton pregnancy. BiB cohort participants were recruited from 2007 to 2010. All women booked for delivery were screened for GDM between 26 and 28 weeks of gestation using a 75 g 2-hour oral glucose tolerance test (OGTT).Outcome measureGDM treatment type: lifestyle changes advice (lifestyle changes), lifestyle changes advice with supplementary insulin (insulin) and lifestyle changes advice with supplementary metformin (metformin).Results244 (32%) women were prescribed lifestyle changes advice alone while 518 (68%) were offered supplemental pharmaceutical treatment. The odds of receiving pharmaceutical treatment relative to lifestyle changes advice alone were increased for mothers who were obese (OR 4.6, 95% CI 2.8 to 7.5), those who smoked (OR 2.6, 95% CI 1.2 to 5.5) and had higher fasting glucose levels at OGTT (OR 2.1, 95% CI 1.6 to 2.7). The odds of being prescribed pharmaceutical treatment rather than lifestyle changes advice were lower for Pakistani women (OR 0.7, 95% CI 0.4 to 1.0)) than White British women. Relative to insulin treatment, metformin was more likely to be offered to obese women than normal weight women (relative risk ratio, RRR 3.2, 95% CI 1.3 to 7.8) and less likely to be prescribed to women with higher fasting glucose concentrations at OGTT (RRR 0.3, 95% CI 0.2 to 0.6).ConclusionsIn the BiB cohort, GDM pharmaceutical treatment tended to be prescribed to women who were obese, White British, who smoked and had more severe hyperglycaemia. The characteristics of metformin-treated mothers differed from those of insulin-treated mothers as they were more likely to be obese but had lower glucose concentrations at diagnosis.

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