scholarly journals Progress in spray-drying of protein pharmaceuticals: Literature analysis of trends in formulation and process attributes

2021 ◽  
pp. 1-32
Author(s):  
Joana T. Pinto ◽  
Eva Faulhammer ◽  
Johanna Dieplinger ◽  
Michael Dekner ◽  
Christian Makert ◽  
...  
2015 ◽  
Vol 30 (5) ◽  
pp. 487 ◽  
Author(s):  
ZHANG Le ◽  
ZHOU Tian-Yuan ◽  
YANG Hao ◽  
QIAO Xue-Bin ◽  
WANG Zhong-Ying ◽  
...  

Author(s):  
Ewa Domian ◽  
Ewa Świrydow ◽  
Jan Cenkier
Keyword(s):  

2018 ◽  
Vol 23 (5-6) ◽  
pp. 347-370 ◽  
Author(s):  
Andy Wai Kan Yeung ◽  
Amr El-Demerdash ◽  
Ioana Berindan-Neagoe ◽  
Atanas G. Atanasov ◽  
Yuh-Shan Ho

Author(s):  
Kusuma P. ◽  
Syukri Y ◽  
Sholehuddin F. ◽  
Fazzri N. ◽  
Romdhonah . ◽  
...  

The most efficient tablet processing method is direct compression. For this method, the filler-binder can be made by coprocessing via spray drying method. The purpose of this study was to investigate the effect of spray dried co-processing on microcrystalline cellulose (MCC) PH 101, lactose and Kollidon® K 30 as well as to define the optimum proportions. Spray dried MCC PH 101, lactose, and Kollidon® K 30 were varied in 13 different mixture design proportions to obtain compact, free-flowing filler-binder co-processed excipients (CPE). Compactibility and flow properties became the key parameters to determine the optimum proportions of CPE that would be compared to their physical mixtures. The result showed that the optimum proportion of CPE had better compactibility and flow properties than the physical mixtures. The optimum CPE, consisting of only MCC PH 101 and Kollidon® K 30 without lactose, that were characterized using infrared spectrophotometer, differential scanning calorimetry (DSC), X-ray diffraction (XRD), and scanning electron microscope (SEM) indicated no chemical change therein. Therefore, this study showed that spray dried MCC PH 101, lactose and Kollidon® K 30 could be one of the filler-binder alternatives for direct compression process.


2019 ◽  
Vol 11 (2) ◽  
Author(s):  
Prasetiyadi Prasetiyadi ◽  
Wiharja Wiharja ◽  
Sri Wahyono

Proses pembakaran sampah kota melalui insinerator akan menghasilkan uap panas yang bisa dimanfaatkan  untuk membangkitkan energi listrik, akan tetapi pada proses ini juga menghasilkan output berupa flue gas yang didominasi oleh partikel (fly ash) dan gas beracun seperti: HCl, SO2, NOx, HF, Hg, Cd dan Dioxin. Sebelum dibuang ke udara bebas, flue gas tersebut harus diolah agar memenuhi baku mutu lingkungan. Teknologi penanganan partikel dan gas polutan tersedia dan dapat dibuat dengan berbagai kapasitas. Untuk menangani flue gas dari insinerator sampah digunakan Quencher untuk menekan laju pembentukan kembali dioksin dan furan setelah proses pembakaran,  Spray Drying Absorption (SDA) untuk mengikat gas asam dan  logam berat serta bag filter untuk menangkap partikel. Selain itu digunakan ID Fan dan Cerobong Asap untuk pengatasi pressure drop yang terjadi akibat pengoperasian peralatan APC dan melepas ke udara.


2011 ◽  
Vol 162 (2) ◽  
pp. 27-31
Author(s):  
Daniel Häuptli

Could there be a win-win situation for both pension funds and the Swiss forestry sector? On the one hand, developments in the forestry sector suggest that the Swiss forest presents a new lucrative investment opportunity. If this is so, then pension funds could be particularly interested, as the low correlation between Swiss forest and other classes of investment, and the long investment periods involved are ideal for pension fund portfolios. On the other hand, large investments made by pension funds could mean that existing problems in Swiss forestry, in connection with its fragmented nature, could be more rapidly solved, and the potential for rationalization in the wood value chain could be fully realized. This would in turn make investments in the forest even more profitable. This hypothesis was investigated through a comprehensive literature analysis, yield calculations for private forestry enterprises of over 50 ha made by the Swiss Federal Office for Statistics 2004–2008, and an interview with the investments director of a large Swiss pension fund. Despite the optimistic assumption that the greater efficiency gained by the investment of pension funds into the forestry sector could lead to costs lower by 50% and a 20% increase in profits, the hypothesis must be rejected, because a calculated annual return of only 0.82% is too low for pension funds. The conclusion is that the price for forest land is high, and forest owners are not only interested in the monetary value of holding forest. Other immaterial values influence prices. It is suggested that a greater emphasis on socioscientific studies concerning the link between the price of forest land and the motivation to buy and sell forest could lead to some important findings.


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