scholarly journals Effects of live yeast (Saccharomyces cerevisiae) as a substitute to antibiotic on growth performance, immune function, serum biochemical parameters and intestinal morphology of broilers

2021 ◽  
Vol 49 (1) ◽  
pp. 15-22
Author(s):  
Tengfei He ◽  
Shad Mahfuz ◽  
Xiangshu Piao ◽  
Di Wu ◽  
Wentao Wang ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Immune Function ◽  
Growth Performance ◽  
Biochemical Parameters ◽  
Intestinal Morphology ◽  
Serum Biochemical Parameters ◽  
Yeast Saccharomyces Cerevisiae ◽  
Serum Biochemical ◽  
Live Yeast

scholarly journals Effects of Probiotics as Antibiotics Substitutes on Growth Performance, Serum Biochemical Parameters, Intestinal Morphology, and Barrier Function of Broilers

Animals ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 985 ◽  
Author(s):  
Tengfei He ◽  
Shenfei Long ◽  
Shad Mahfuz ◽  
Di Wu ◽  
Xi Wang ◽  
...  
Keyword(s):  
Organic Matter ◽  
Growth Performance ◽  
Biochemical Parameters ◽  
Dry Matter ◽  
Phase 1 ◽  
Basal Diet ◽  
Intestinal Morphology ◽  
Serum Biochemical Parameters ◽  
Phase 2 ◽  
Serum Biochemical

The aim of this study was to investigate the effects of the combination of probiotics replacing antibiotics on growth performance, serum biochemical parameters, intestinal morphology, and expression of tight junction proteins in intestinal mucosa of broilers. A total of 168 Arbor Acres broilers (45.04 ± 0.92 g) were randomly divided into three treatments, with seven replicates per treatment, and eight broilers per replicate. The experiment included phases 1 (d 0 to 21) and 2 (d 21 to 42). The dietary treatments contained a corn soybean meal-based diet (control group; CON); an antibiotic group (basal diet + 75 mg/kg chlortetracycline; CTC), and a probiotics group (basal diet + probiotics (500 mg/kg in phase 1 and 300 mg/kg in phase 2; Bacillus subtilis 5 × 109 CFU/g, Bacillus licheniformis 2.5 × 1010 CFU/g and Saccharomyces cerevisiae 1 × 109 CFU/g; PB). The results showed broilers fed PB had improved (p < 0.05) feed conversion ratio (FCR) in phase 1 and increased (p < 0.05) average daily gain (ADG) in phase 2, as well as improved (p < 0.05) ADG and FCR overall (d 0 to 42). The apparent total tract digestibility (ATTD) of dry matter, organic matter, gross energy, and crude protein was increased (p < 0.05) in broilers fed PB, while the ATTD of dry matter and organic matter was enhanced in broilers fed CTC compared with CON. Broilers fed PB showed increased (p < 0.05) serum total antioxidant capacity concentrations and tended to have higher (p = 0.06) level of serum immunoglobulin M in phase 1 compared with CON. These broilers also had increased (p < 0.05) level of serum immunoglobulin A in phase 2 in comparison with CON and CTC. Moreover, broilers fed CTC and PB showed increased (p = 0.05) villus height to crypt depth ratio in duodenum, as well as higher (p < 0.05) mRNA expression of zonula occludens-1 in jejunum compared with CON. In conclusion, dietary supplementation with PB as chlortetracycline substitute could improve the growth performance, nutrient digestibility, serum antioxidant capacity, jejunal mucosal barrier function, and intestinal morphology of broilers.

scholarly journals Effects of Bacillus megaterium on growth performance, serum biochemical parameters, antioxidant capacity, and immune function in suckling calves

2020 ◽  
Vol 15 (1) ◽  
pp. 1033-1041 ◽  
Author(s):  
Jun Yao ◽  
Lili Wang ◽  
Wenju Zhang ◽  
Mengjian Liu ◽  
Junli Niu
Keyword(s):  
Antioxidant Capacity ◽  
Immune Function ◽  
Growth Performance ◽  
Bacillus Megaterium ◽  
Biochemical Parameters ◽  
Basal Diet ◽  
Daily Weight Gain ◽  
Control Group ◽  
Serum Biochemical Parameters ◽  
Serum Biochemical

AbstractBackgroundThis study was conducted to investigate the effects of Bacillus megaterium on growth performance, serum biochemical parameters, antioxidant capacity, and immune function in suckling calves.MethodsIn total, 20 1-day-old Holstein calves with similar body weight (BW) and good health condition were randomly assigned into two groups with ten replicates per group and one calf per replicate. The control group (CON group) was fed a basal diet, whereas the B. megaterium group (BM group) was fed the basal diet supplemented with 500 mg/day/head of B. megaterium (1010 CFU/g) for 28 days.ResultsThe results revealed that the BM group showed an increase in final BW, daily weight gain, and feed-to-gain ratio (p < 0.05) and a decrease in diarrhea rate. Moreover, the concentrations of serum cholesterol and high-density lipoprotein decreased (p < 0.05) in the BM group compared with the CON group at 28 days. The level of serum glutathione was higher (p < 0.05) in the BM group than that of the CON group at 14 days, whereas the level of serum malondialdehyde decreased (p < 0.01) in the BM group compared with the CON group at 28 days. In addition, compared with the CON group (p < 0.05), the concentrations of serum IgA, IgM, IgG, and IL-4 were higher, whereas the concentration of serum TNF-α decreased in the BM group at 28 days.ConclusionB. megaterium had beneficial effects on the improvement of growth performance, immune function, and intestinal oxidative status of suckling calves.

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