The relationship of red meat with cancer: Effects of thermal processing and related physiological mechanisms

2015 ◽  
Vol 57 (6) ◽  
pp. 1153-1173 ◽  
Author(s):  
Vic Shao-Chih Chiang ◽  
Siew-Young Quek
2020 ◽  
Author(s):  
Parveen Kumar Deralia ◽  
Aline Maire du Poset ◽  
Anja Lund ◽  
Anette Larsson ◽  
Anna Ström ◽  
...  

Herein we present arabinoxylan (AX)-based thermoplastics obtained by ring opening oxidation and subsequent reduction (dA-AX) combined with hydrophobization with three different glycidyl ethers [n-butyl (BuGE), isopropyl (iPrGE) and 2-ethylhexyl (EtHGE) glycidyl ether]. We also present the relationship of structural composition, thermal processing and thermomechanical properties. The BuGE and iPrGE etherified dA-AXs showed glass transition temperatures (T<sub>g</sub>) far below their degradation temperatures and gave thermoplastic materials when compression-molded at 140˚C. The BuGE (3 mole) etherified dA-AX films at 19 and 31 % oxidation levels exclusively exhibit 244 % (±42) and 267 % (±72) elongation. In contrast, iPrGE-dA-AX samples with shorter and branched terminals in the side chains had maximum 60 % (±19) elongation. The dramatic difference in elongation is assumed to be due to the presence of longer alkoxide chains, higher molar substitution and dual T<sub>g</sub> for the BuGE samples. Such superior elongation of AX thermoplastic films and its relationship with molar substitution and T<sub>g</sub> has not been reported before.


2020 ◽  
Vol 27 (2) ◽  
pp. 66-75
Author(s):  
Björn Pannicke ◽  
Julia Reichenberger ◽  
Dana Schultchen ◽  
Olga Pollatos ◽  
Jens Blechert

Abstract. Objectives: Physical activity (PA) positively influences several aspects of mental well-being including affect improvements. Yet, the fact that subjective and objective measures of PA often diverge challenges research on the relationship of PA and affect. Methods: Subjective (ecological momentary assessment, EMA) and objective (combined heart rate and accelerometric activity tracker) measures of PA alongside repeated ratings of positive and negative affects were obtained from 37 participants over 7 consecutive days. Results: Subjective and objective PA were significantly positively correlated. Affect improvements, that is, negative affect decrease as well as positive affect increase, were predicted by both subjective (EMA) and objective (activity tracker) data. Conclusions: Measurement concordance supports the validity of both assessment strategies. Affect improvements result from both subjective representations of one’s own activity as well as from physiological mechanisms of PA that one is not aware of, suggesting two independent routes to affect improvements.


2020 ◽  
Author(s):  
Parveen Kumar Deralia ◽  
Aline Maire du Poset ◽  
Anja Lund ◽  
Anette Larsson ◽  
Anna Ström ◽  
...  

Herein we present arabinoxylan (AX)-based thermoplastics obtained by ring opening oxidation and subsequent reduction (dA-AX) combined with hydrophobization with three different glycidyl ethers [n-butyl (BuGE), isopropyl (iPrGE) and 2-ethylhexyl (EtHGE) glycidyl ether]. We also present the relationship of structural composition, thermal processing and thermomechanical properties. The BuGE and iPrGE etherified dA-AXs showed glass transition temperatures (T<sub>g</sub>) far below their degradation temperatures and gave thermoplastic materials when compression-molded at 140˚C. The BuGE (3 mole) etherified dA-AX films at 19 and 31 % oxidation levels exclusively exhibit 244 % (±42) and 267 % (±72) elongation. In contrast, iPrGE-dA-AX samples with shorter and branched terminals in the side chains had maximum 60 % (±19) elongation. The dramatic difference in elongation is assumed to be due to the presence of longer alkoxide chains, higher molar substitution and dual T<sub>g</sub> for the BuGE samples. Such superior elongation of AX thermoplastic films and its relationship with molar substitution and T<sub>g</sub> has not been reported before.


Paleobiology ◽  
1980 ◽  
Vol 6 (02) ◽  
pp. 146-160 ◽  
Author(s):  
William A. Oliver

The Mesozoic-Cenozoic coral Order Scleractinia has been suggested to have originated or evolved (1) by direct descent from the Paleozoic Order Rugosa or (2) by the development of a skeleton in members of one of the anemone groups that probably have existed throughout Phanerozoic time. In spite of much work on the subject, advocates of the direct descent hypothesis have failed to find convincing evidence of this relationship. Critical points are:(1) Rugosan septal insertion is serial; Scleractinian insertion is cyclic; no intermediate stages have been demonstrated. Apparent intermediates are Scleractinia having bilateral cyclic insertion or teratological Rugosa.(2) There is convincing evidence that the skeletons of many Rugosa were calcitic and none are known to be or to have been aragonitic. In contrast, the skeletons of all living Scleractinia are aragonitic and there is evidence that fossil Scleractinia were aragonitic also. The mineralogic difference is almost certainly due to intrinsic biologic factors.(3) No early Triassic corals of either group are known. This fact is not compelling (by itself) but is important in connection with points 1 and 2, because, given direct descent, both changes took place during this only stage in the history of the two groups in which there are no known corals.


Author(s):  
D. F. Blake ◽  
L. F. Allard ◽  
D. R. Peacor

Echinodermata is a phylum of marine invertebrates which has been extant since Cambrian time (c.a. 500 m.y. before the present). Modern examples of echinoderms include sea urchins, sea stars, and sea lilies (crinoids). The endoskeletons of echinoderms are composed of plates or ossicles (Fig. 1) which are with few exceptions, porous, single crystals of high-magnesian calcite. Despite their single crystal nature, fracture surfaces do not exhibit the near-perfect {10.4} cleavage characteristic of inorganic calcite. This paradoxical mix of biogenic and inorganic features has prompted much recent work on echinoderm skeletal crystallography. Furthermore, fossil echinoderm hard parts comprise a volumetrically significant portion of some marine limestones sequences. The ultrastructural and microchemical characterization of modern skeletal material should lend insight into: 1). The nature of the biogenic processes involved, for example, the relationship of Mg heterogeneity to morphological and structural features in modern echinoderm material, and 2). The nature of the diagenetic changes undergone by their ancient, fossilized counterparts. In this study, high resolution TEM (HRTEM), high voltage TEM (HVTEM), and STEM microanalysis are used to characterize tha ultrastructural and microchemical composition of skeletal elements of the modern crinoid Neocrinus blakei.


Author(s):  
Leon Dmochowski

Electron microscopy has proved to be an invaluable discipline in studies on the relationship of viruses to the origin of leukemia, sarcoma, and other types of tumors in animals and man. The successful cell-free transmission of leukemia and sarcoma in mice, rats, hamsters, and cats, interpreted as due to a virus or viruses, was proved to be due to a virus on the basis of electron microscope studies. These studies demonstrated that all the types of neoplasia in animals of the species examined are produced by a virus of certain characteristic morphological properties similar, if not identical, in the mode of development in all types of neoplasia in animals, as shown in Fig. 1.


Author(s):  
J.R. Pfeiffer ◽  
J.C. Seagrave ◽  
C. Wofsy ◽  
J.M. Oliver

In RBL-2H3 rat leukemic mast cells, crosslinking IgE-receptor complexes with anti-IgE antibody leads to degranulation. Receptor crosslinking also stimulates the redistribution of receptors on the cell surface, a process that can be observed by labeling the anti-IgE with 15 nm protein A-gold particles as described in Stump et al. (1989), followed by back-scattered electron imaging (BEI) in the scanning electron microscope. We report that anti-IgE binding stimulates the redistribution of IgE-receptor complexes at 37“C from a dispersed topography (singlets and doublets; S/D) to distributions dominated sequentially by short chains, small clusters and large aggregates of crosslinked receptors. These patterns can be observed (Figure 1), quantified (Figure 2) and analyzed statistically. Cells incubated with 1 μg/ml anti-IgE, a concentration that stimulates maximum net secretion, redistribute receptors as far as chains and small clusters during a 15 min incubation period. At 3 and 10 μg/ml anti-IgE, net secretion is reduced and the majority of receptors redistribute rapidly into clusters and large aggregates.


1993 ◽  
Vol 2 (3) ◽  
pp. 52-55 ◽  
Author(s):  
Michael Collins ◽  
Robert McDonald ◽  
Robert Stanley ◽  
Timothy Donovan ◽  
C. Frank Bonebrake

This report describes an unusual and persistent dysphonia in two young women who had taken a therapeutic regimen of isotretinoin for intractable acne. We report perceptual and instrumental data for their dysphonia, and pose a theoretical basis for the relationship of dysphonia to this drug. We also provide recommendations for reducing the risk of acquiring a dysphonia during the course of treatment with isotretinoin.


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