scholarly journals In vitro biomechanical properties, fluorescence imaging, surface-enhanced Raman spectroscopy, and photothermal therapy evaluation of luminescent functionalized CaMoO4:Eu@Au hybrid nanorods on human lung adenocarcinoma epithelial cells

2016 ◽  
Vol 17 (1) ◽  
pp. 346-360 ◽  
Author(s):  
Qifei Li ◽  
Abdul K. Parchur ◽  
Anhong Zhou
Nanomaterials ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 1145 ◽  
Author(s):  
Shuvashis Dey ◽  
Matt Trau ◽  
Kevin M. Koo

Cancer immunotherapy encompasses a variety of approaches which target or use a patient’s immune system components to eliminate cancer. Notably, the current use of immune checkpoint inhibitors to target immune checkpoint receptors such as CTLA-4 or PD-1 has led to remarkable treatment responses in a variety of cancers. To predict cancer patients’ immunotherapy responses effectively and efficiently, multiplexed immunoassays have been shown to be advantageous in sensing multiple immunomarkers of the tumor microenvironment simultaneously for patient stratification. Surface-enhanced Raman spectroscopy (SERS) is well-regarded for its capabilities in multiplexed bioassays and has been increasingly demonstrated in cancer immunotherapy applications in recent years. This review focuses on SERS-active nanomaterials in the modern literature which have shown promise for enabling cancer patient-tailored immunotherapies, including multiplexed in vitro and in vivo immunomarker sensing and imaging, as well as immunotherapy drug screening and delivery.


2017 ◽  
Vol 19 (suppl_6) ◽  
pp. vi159-vi159 ◽  
Author(s):  
Hamed Arami ◽  
Edwin Chang ◽  
Chirag B Patel ◽  
Steven James Madsen ◽  
Ryan Miller Davis ◽  
...  

2019 ◽  
Vol 10 (47) ◽  
pp. 10900-10910 ◽  
Author(s):  
Yingfang Xing ◽  
Zhewei Cai ◽  
Meijuan Xu ◽  
Wenzheng Ju ◽  
Xiaojun Luo ◽  
...  

A molecular signaling pathway of apoptosis induced by photothermal therapy was revealed by surface-enhanced Raman spectroscopy.


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