Simultaneous Time-Dependent Surface-Enhanced Raman Spectroscopy, Metabolomics, and Proteomics Reveal Cancer Cell Death Mechanisms Associated with Gold Nanorod Photothermal Therapy

2016 ◽  
Vol 138 (47) ◽  
pp. 15434-15442 ◽  
Author(s):  
Moustafa R. K. Ali ◽  
Yue Wu ◽  
Tiegang Han ◽  
Xiaoling Zang ◽  
Haopeng Xiao ◽  
...  
2017 ◽  
Vol 19 (suppl_6) ◽  
pp. vi159-vi159 ◽  
Author(s):  
Hamed Arami ◽  
Edwin Chang ◽  
Chirag B Patel ◽  
Steven James Madsen ◽  
Ryan Miller Davis ◽  
...  

2019 ◽  
Vol 10 (47) ◽  
pp. 10900-10910 ◽  
Author(s):  
Yingfang Xing ◽  
Zhewei Cai ◽  
Meijuan Xu ◽  
Wenzheng Ju ◽  
Xiaojun Luo ◽  
...  

A molecular signaling pathway of apoptosis induced by photothermal therapy was revealed by surface-enhanced Raman spectroscopy.


Nanoscale ◽  
2014 ◽  
Vol 6 (15) ◽  
pp. 8612-8616 ◽  
Author(s):  
Xianghu Tang ◽  
Wenya Cai ◽  
Liangbao Yang ◽  
Jinhuai Liu

The kinetics of the reaction of 4-NTP dimerizing into DMAB was investigated and comparative studied using a SERS technique on a single particle.


Nanomedicine ◽  
2021 ◽  
Author(s):  
Anindita Das ◽  
Vinothini Arunagiri ◽  
Hsieh-Chih Tsai ◽  
Adhimoorthy Prasannan ◽  
Juin-Yih Lai ◽  
...  

Aim: To prepare efficient metal-semiconductor nanoparticles as noninvasive, real-time imaging probes for photothermal therapy (PTT) applications. Materials & methods: A bottom-up approach was used to fabricate core-shell Ag@CuS nanoparticles (NPs). PTT and Raman mapping were done using HeLa cells. Theoretical simulation of electric field enhancement and heat dissipation density of Ag@CuS NPs was performed. Results: PTT-induced hyperthermia was achieved under 940 nm near-infrared light irradiation. Surface-enhanced Raman spectroscopy (SERS) signals of dye molecules were observed when conjugated with Ag@CuS NPs. Conclusion: Ag@CuS NPs are found to be efficient for SERS imaging and localized heating under laser irradiation, making a promising candidate for SERS-guided PTT.


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