Stigma and Genetic Risk: Perceptions of Stigma among Those at Risk for Huntington Disease (HD)∗

2007 ◽  
Vol 4 (1-2) ◽  
pp. 65-84 ◽  
Author(s):  
Holly Etchegary
2011 ◽  
Author(s):  
Camille D. Basilio ◽  
Kelli Byrnes ◽  
Angela G. Pirlott ◽  
Virginia S. Y. Kwan ◽  
Leona S. Aiken

2011 ◽  
Vol 81 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Y Bombard ◽  
A Semaka ◽  
MR Hayden

Author(s):  
Karim Raza ◽  
Catherine McGrath ◽  
Laurette van Boheemen ◽  
Dirkjan van Schaardenburg

The typical evolution of rheumatoid arthritis (RA) is that a person, with genetic risk factors, develops autoantibodies and subclinical inflammation under relevant environmental influences. There are indications that the primary site of the pathology is at mucosal surfaces (e.g. in the gums, lungs, and/or the gut), after which the disease translocates to the joints. Preclinical RA can be defined at the phase during which no clinically apparent features are present (i.e. no symptoms of inflammatory arthritis or clinically apparent joint swelling) but during which RA related biologic derangements such as the presence of autoantibodies are present. This chapter presents an overview of the risk factors, stages, and events occurring during the pre-RA phase. A better understanding of the factors involved will enable more accurate prediction of RA at the individual level and selection of high-risk individuals for inclusion in preventive studies. Several pharmacologic and non-pharmacologic studies aiming to prevent or delay the onset of RA in at-risk individuals are currently underway. It is hoped that such interventions in the pre-RA and indeed in the preclinical-RA phases will allow us to reduce the risk of RA and prevent RA developing in at least a proportion of at-risk patients.


1987 ◽  
Vol 26 (2) ◽  
pp. 295-305 ◽  
Author(s):  
Dorene S. Markel ◽  
Anne B. Young ◽  
John B. Penney ◽  
John M. Opitz ◽  
James F. Reynolds

2018 ◽  
Vol 27 (6) ◽  
pp. 1428-1437 ◽  
Author(s):  
K. M. Stuttgen ◽  
J. M. Bollinger ◽  
R. L. Dvoskin ◽  
A. McCague ◽  
B. Shpritz ◽  
...  

Cancer ◽  
2016 ◽  
Vol 122 (22) ◽  
pp. 3564-3575
Author(s):  
Aubrey R. Turner ◽  
Brian R. Lane ◽  
Dan Rogers ◽  
Isaac Lipkus ◽  
Kathryn Weaver ◽  
...  

2016 ◽  
Vol 11 (4) ◽  
pp. 742-753 ◽  
Author(s):  
Md. Nasif Ahsan ◽  
◽  
Kuniyoshi Takeuchi ◽  
Karina Vink ◽  
Miho Ohara ◽  
...  

Researchers are investigating a broad spectrum of factors affecting positively and/or negatively the evacuation decision-making process occurring after people at risk receive cyclone warnings and advisories. Previous studies suggest that early warnings themselves do not propagate evacuation processes to be investigated but, rather, that human risk perceptions do so. This in turn encourages the sociopsychological dimensions of risk perception to be evaluated, which must be done within a country’s own cultural context. In applying content analysis here, we review the literature on evacuation decision-making processes during rapidonset hazards, i.e., tropical cyclones, in coastal Bangladesh. We focus on three broad overlapping themes – early warning, risk perception, and evacuation decision-making. Major content-analysis findings suggest that two things – a lack of credibility in early warning messages and an inefficient dissemination process – tend to affect the risk perception of people at risk and are likely to eventually determine the success of evacuation decision-making. Findings also show that different socioeconomic and socio-cultural issues related to risk perception appear to be more influential than formal warning messages in propagating decisions to evacuate during a cyclone. Based on these results, we suggest specific policy recommendations for improving local evacuation efficiency.


Sign in / Sign up

Export Citation Format

Share Document